Answered BIOCHEM 551 Quiz 3 Re-Updated- Louisiana University.

Question 1 1.5 out of 1.5 points Patients with Type II DM due to insulin resistance tend to also have Type IV hypertriglyceridemia possibly as a result of __________? Selected Answer: Decrease lipoprotein lipase activity  Question 2 1.5 out of 1.5 points Which of these statements about Proprotein convertase subtilisin/kexin-9 (PCSK-9) is most accurate? Selected Answer: Antibodies that block the action of PCSK-9 will reduce plasma LDL levels  Question 3 0 out of 1.5 points The production of apoB-48 from the full-length apoB100 gene is accomplished by the enzyme _____________ which produces deoxyuracil at position 6666 of the apoB mRNA resulting in a stop codon? Selected Answer: Cytosine deaminase (apobec-1) in hepatocytes Correct answer is: cytosine deaminase (apobec-1) in enterocytes  Question 4 0 out of 1.5 points Microsomal triglyceride transfer protein plays a major role in lipoprotein assembly by which of these mechanisms? Selected Answer: Facilitating the transfer of lipids from the membrane to nascent aopB Also not: Facilitating the import of triglycerides into the ER for lipoprotein assembly  Question 5 1.5 out of 1.5 points Lipoprotein lipase on the capillaries of adipose tissues is activated by what component of VLDLs? Selected Answer: Apo CII  Question 6 1.5 out of 1.5 points Chylomicron retention disease is a genetic disorder characterized by a malabsorbtion of dietary lipids, fatty stool, accumulation of intestinal triglycerides and hypolipoproteinemia. A deficiency of which apoprotein is most likely responsible for this disorder? Selected Answer: Apo B48  Question 7 1.5 out of 1.5 points Which of these has the greatest affinity for LDL receptors? Selected Answer: apo E  Question 8 1.5 out of 1.5 points Which of these is not consistent with a case of Familial hypercholesterolemia? Selected Answer: Decreased HDL  Question 9 1.5 out of 1.5 points Which of these is not a function of cholesterol? Selected Answer: Albumin synthesis  Question 10 1.5 out of 1.5 points Chylomicron retention disease is a genetic disorder characterized by a malabsorption of dietary lipids, fatty stool, accumulation of intestinal triglycerides and hypolipoproteinemia. A deficiency of which apoprotein is most likely responsible for this disorder? Selected Answer: Apo B48  Question 11 1.5 out of 1.5 points An increased transcriptional activity of SREBP will result in;