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, Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International GCSE (9–1)
Time 1 hour 15 minutes
Paper
reference 4BI1/2B
Biology
UNIT: 4BI1
PAPER: 2B
You must have: Total Marks
Calculator, ruler
Instructions
• Use black ink or ball‑point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• Answer the questions in the spaces provided
– there may be more space than you need.
• Show all the steps in any calculations and state the units.
• Some questions must be answered with a cross in a box . If you change your
mind about an answer, put a line through the box and then mark your new
answer with a cross .
Information
• The total mark for this paper is 70.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
Advice
• Read each question carefully before you start to answer it.
• Write your answers neatly and in good English.
• Try to answer every question.
• your answers if you have time at the end.
Check
Turn over
*P69608A0128*
P69608A
©2022 Pearson Education Ltd.
L:1/1/1/1/1/1/
, Answer ALL questions.
1 Read the passage below. Use the information in the passage and your own
knowledge to answer the questions that follow.
Making Enough Blood for the World
A blood transfusion is the transfer of blood from a donor into a patient. Blood
transfusions are routine medical procedures that save the lives of millions of
people every year.
(Source: beerkoff/Shutterstock)
The first successful blood transfusions were performed in the early twentieth
5 century after scientists discovered that there are four main blood groups, A,
B, AB and O. The blood groups are due to the presence of proteins, called
antigens, on the surface of red blood cells. There are two main protein
antigens called A and B. If a patient is given blood with antigens different
to their own cells, their immune system will make antibodies against that
10 antigen. The antigens present on the surface of red blood cells for each blood
group are shown in the table.
Blood group Antigens present
A A
B B
AB A and B
O neither A nor B
Currently, blood transfusions are carried out with blood that has been
donated by healthy people. The World Health Organisation calculates that
there are 118.5 million blood donations collected globally every year. Of these
15 donations, 40% are collected from a small group of high‑income countries.
This means that there is a shortage of blood in many countries so the hunt is
on to find an alternative.
2
*P69608A0228*
question sets and mock sets visit https://tyrionpapers.com/ or
insta:tyrionpapers or email
, Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International GCSE (9–1)
Time 1 hour 15 minutes
Paper
reference 4BI1/2B
Biology
UNIT: 4BI1
PAPER: 2B
You must have: Total Marks
Calculator, ruler
Instructions
• Use black ink or ball‑point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• Answer the questions in the spaces provided
– there may be more space than you need.
• Show all the steps in any calculations and state the units.
• Some questions must be answered with a cross in a box . If you change your
mind about an answer, put a line through the box and then mark your new
answer with a cross .
Information
• The total mark for this paper is 70.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
Advice
• Read each question carefully before you start to answer it.
• Write your answers neatly and in good English.
• Try to answer every question.
• your answers if you have time at the end.
Check
Turn over
*P69608A0128*
P69608A
©2022 Pearson Education Ltd.
L:1/1/1/1/1/1/
, Answer ALL questions.
1 Read the passage below. Use the information in the passage and your own
knowledge to answer the questions that follow.
Making Enough Blood for the World
A blood transfusion is the transfer of blood from a donor into a patient. Blood
transfusions are routine medical procedures that save the lives of millions of
people every year.
(Source: beerkoff/Shutterstock)
The first successful blood transfusions were performed in the early twentieth
5 century after scientists discovered that there are four main blood groups, A,
B, AB and O. The blood groups are due to the presence of proteins, called
antigens, on the surface of red blood cells. There are two main protein
antigens called A and B. If a patient is given blood with antigens different
to their own cells, their immune system will make antibodies against that
10 antigen. The antigens present on the surface of red blood cells for each blood
group are shown in the table.
Blood group Antigens present
A A
B B
AB A and B
O neither A nor B
Currently, blood transfusions are carried out with blood that has been
donated by healthy people. The World Health Organisation calculates that
there are 118.5 million blood donations collected globally every year. Of these
15 donations, 40% are collected from a small group of high‑income countries.
This means that there is a shortage of blood in many countries so the hunt is
on to find an alternative.
2
*P69608A0228*
