BIOCHEM C785 WGU MODULE 2 COMPLETE EXAMS
Deedra's dad has Alzheimer's Disease (AD) which is caused by a change
in protein structure - True
Alzheimer's disease is caused by aggregation of the Amyloid beta peptide
and tangle formation by the tau protein. What kinds of amino acids are
likely to drive the formation of these protein aggregates? - hydrophobic
After learning about Alzheimer's disease and one of the drugs used in its
treatment, what other drug design strategies could you use to offer
treatment for AD? - 1. Drugs that break up the amyloid plaques
2. Drugs that block the production of amyloid beta peptide
3. drugs that inhibits the aggregation of protein structures
A substrate binds to an enzyme at a specific site is referred to as - an
active site
You are in charge of designing a drug that inhibits the activity of a specific
enzyme. An important criteria for the drug selection is to ensure that the
drug is directly in competition with the original substrate when binding to
the active site of the enzyme. What inhibitor would be an ideal choice? - A
competitive inhibitor
These factors can affect the protein folding and activity of an enzyme: - 1.
pH
2. Heat
3. Reducing agents
One way a cell can avoid overproduction of a molecule is by using a
particular type of inhibition in which the molecule itself acts as an inhibitor
for an enzyme in its production pathway. This type of regulation is known
as feedback inhibition - True
What type of enzyme adds a phosphate to another molecule? - Kinase
What are possible effects that phosphorylation/dephosphorylation can have
on the activity of an enzyme? - 1. turn the enzyme on
2. turn the enzyme off
Deedra's dad has Alzheimer's Disease (AD) which is caused by a change
in protein structure - True
Alzheimer's disease is caused by aggregation of the Amyloid beta peptide
and tangle formation by the tau protein. What kinds of amino acids are
likely to drive the formation of these protein aggregates? - hydrophobic
After learning about Alzheimer's disease and one of the drugs used in its
treatment, what other drug design strategies could you use to offer
treatment for AD? - 1. Drugs that break up the amyloid plaques
2. Drugs that block the production of amyloid beta peptide
3. drugs that inhibits the aggregation of protein structures
A substrate binds to an enzyme at a specific site is referred to as - an
active site
You are in charge of designing a drug that inhibits the activity of a specific
enzyme. An important criteria for the drug selection is to ensure that the
drug is directly in competition with the original substrate when binding to
the active site of the enzyme. What inhibitor would be an ideal choice? - A
competitive inhibitor
These factors can affect the protein folding and activity of an enzyme: - 1.
pH
2. Heat
3. Reducing agents
One way a cell can avoid overproduction of a molecule is by using a
particular type of inhibition in which the molecule itself acts as an inhibitor
for an enzyme in its production pathway. This type of regulation is known
as feedback inhibition - True
What type of enzyme adds a phosphate to another molecule? - Kinase
What are possible effects that phosphorylation/dephosphorylation can have
on the activity of an enzyme? - 1. turn the enzyme on
2. turn the enzyme off
