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Step 2 Drugs (mult. choice) QUESTIONS AND ANSWERS (SCORES 100%)

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Step 2 Drugs (mult. choice) Should always be given to a patient with stable angina who also has hypertension Correct Answer: beta-blocker Given to *all* patients with coronary artery disease. Decreases morbidity and reduces risk of MI Correct Answer: aspirin Low molecular weight heparin Correct Answer: enoxaparin Best drug for a young adult female with chest pain waking her up at night Correct Answer: diltiazem Proven to reduce ventricular remodeling in myocardial infarction Correct Answer: ACE inhibitor Best drug for treating "flash" pulmonary edema in an MI patient Correct Answer: furosemide The combination of this and a diuretic is first-line treatment in CHF Correct Answer: ACE inhibitor Give this for low ejection fraction in CHF Correct Answer: digitalis Treatment for unstable afib Correct Answer: cardioversion Treatment for narrow-complex tachycardias Correct Answer: adenosine Treatment for wide-complex tachycardias Correct Answer: amiodarone Antiarrythmic for which pulmonary fibrosis is a side effect Correct Answer: amiodarone First-line treatment for rate control in afib Correct Answer: amlodipine Best drug for WPW syndrome (until radiofrequency ablation can be performed) Correct Answer: Procainamide Best drug for a patient with tricyclic antidepressant toxicity who develops the characteristic arrhythmia Correct Answer: magnesium Usually second-degree Mobitz Type 1 heart block (Wenkebach) does not need treatment, but if the patient is unstable, give: Correct Answer: atropine Aside from treating the underlying cause, give this for acute pericarditis Correct Answer: NSAIDs Inhaled anticholinergic drug given after albuterol (with which it has a synergistic effect) for COPD Correct Answer: ipratropium Controversial drug (due to side effects) that may improve mucus clearance in COPD Correct Answer: theophylline COPD treatment (not first-line) that has serious toxicity with ciprofloxacin or erythromycin Correct Answer: theophylline Given for asthma prophylaxis (i.e. before exercise) mainly in children and hardly ever in adults Correct Answer: cromolyn/nedocromil sodium This can be injected directly into the SMA to alleviate the effects of a clot by causing vasodilation Correct Answer: papaverine First-line therapy for bleeding esophageal varices. Causes splanchnic vasoconstriction, reducing portal pressure Correct Answer: octreotide Given for hepatic encephalopathy because it prevents absorption of ammonia in GI tract, enabling its excretion Correct Answer: laculose Given for hepatic encaphalopathy because it kills bowel flora, thus decreasing ammonia production Correct Answer: neomycin Copper chelator given for Wilson's disease (hepatolenticular degeneration) Correct Answer: penicillamine In addition to a copper chelator, this may also be given for Wilson's disease (hepatolenticular degeneration) because it inhibits uptake of dietary copper Correct Answer: zinc Treatment for hemochromatosis Correct Answer: repeated phlebotomy

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Step 2 Drugs (mult. choice)
Should always be given to a patient with stable angina who also has hypertension Correct Answer: beta-
blocker

Given to *all* patients with coronary artery disease. Decreases morbidity and reduces risk of MI Correct
Answer: aspirin

Low molecular weight heparin Correct Answer: enoxaparin

Best drug for a young adult female with chest pain waking her up at night Correct Answer: diltiazem

Proven to reduce ventricular remodeling in myocardial infarction Correct Answer: ACE inhibitor

Best drug for treating "flash" pulmonary edema in an MI patient Correct Answer: furosemide

The combination of this and a diuretic is first-line treatment in CHF Correct Answer: ACE inhibitor

Give this for low ejection fraction in CHF Correct Answer: digitalis

Treatment for unstable afib Correct Answer: cardioversion

Treatment for narrow-complex tachycardias Correct Answer: adenosine

Treatment for wide-complex tachycardias Correct Answer: amiodarone

Antiarrythmic for which pulmonary fibrosis is a side effect Correct Answer: amiodarone

First-line treatment for rate control in afib Correct Answer: amlodipine

Best drug for WPW syndrome (until radiofrequency ablation can be performed) Correct Answer:
Procainamide

Best drug for a patient with tricyclic antidepressant toxicity who develops the characteristic arrhythmia
Correct Answer: magnesium

Usually second-degree Mobitz Type 1 heart block (Wenkebach) does not need treatment, but if the
patient is unstable, give: Correct Answer: atropine

Aside from treating the underlying cause, give this for acute pericarditis Correct Answer: NSAIDs

Inhaled anticholinergic drug given after albuterol (with which it has a synergistic effect) for COPD
Correct Answer: ipratropium

, Controversial drug (due to side effects) that may improve mucus clearance in COPD Correct Answer:
theophylline

COPD treatment (not first-line) that has serious toxicity with ciprofloxacin or erythromycin Correct
Answer: theophylline

Given for asthma prophylaxis (i.e. before exercise) mainly in children and hardly ever in adults Correct
Answer: cromolyn/nedocromil sodium

This can be injected directly into the SMA to alleviate the effects of a clot by causing vasodilation Correct
Answer: papaverine

First-line therapy for bleeding esophageal varices. Causes splanchnic vasoconstriction, reducing portal
pressure Correct Answer: octreotide

Given for hepatic encephalopathy because it prevents absorption of ammonia in GI tract, enabling its
excretion Correct Answer: laculose

Given for hepatic encaphalopathy because it kills bowel flora, thus decreasing ammonia production
Correct Answer: neomycin

Copper chelator given for Wilson's disease (hepatolenticular degeneration) Correct Answer:
penicillamine

In addition to a copper chelator, this may also be given for Wilson's disease (hepatolenticular
degeneration) because it inhibits uptake of dietary copper Correct Answer: zinc

Treatment for hemochromatosis Correct Answer: repeated phlebotomy

Best drug for a middle-aged woman with pruritis, jaundice, xanthalesma, RUQ pain, and positive
antimitochondrial antibodies (at least until liver transplantation can be performed) Correct Answer:
Ursodeoxycholic acid

Can be given to reduce the risk of ulcer formation in patients on chronic NSAID therapy Correct Answer:
misoprostol

Reduces the risk of NSAID-induced stomach ulcers but female patients must not get pregnant while on it
because it stimulates uterine contractions which can lead to spont. abortion Correct Answer:
misoprostol

First-line maintenance treatment for ulcerative colitis Correct Answer: Sulfasalazine (5-ASA)

Given for hyperthyroidism (Inhibits thyroid hormone synthesis) Correct Answer: thionamides
(methimazole)

Given for hyperthyroidism (inhibits formation of T3 from T4) Correct Answer: Propylthiouracil (PTU)

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