1. Cell manipulation via Gene editing
CRISPR/Cas 9
CRISPR /cas a changes DNA
leads to Changes in protein exp.
Changes in protein exp
Changes in machinery & cell behavior
2.Synthetic biology
3. Affordable genome sequencing
Cell biology = genetics, biochemistry, Cytology
Lecture 1B: Little bit of history,
1660 = microscopes
Robert Hooke
- cork > term "cell”, 30X
Cellular= little room
- world's first cell bio textbook = micrographia
- 1670's - Leeuwenhoek
Dutch textile merchant
300X
made many microscopes
blood, bacteria, teeth, sperm cells
animalcules
recorded his findings with drawings and letters of observation
Cell theory