Cellular pathology
, Cell injury & Cellular Adaptive Changes
a) Physical agents
• Trauma, Burn, pressure, irradiation
b) Chemical agents; Poisons and drugs
c) Micro organisms- Bacteria, Virus, Fungus and
Parasites
d) Genetic defects; Can affect cellular metabolism
through inborn errors of metabolism or gross
malformation
, e) Hypoxia
• Is the most common stimuli (cause)
• Is because of inadequate oxygen in the blood
or decreased tissue Perfusion.
f) Nutritional imbalances ; Under nutrition or
over nutrition causes cellular injury or
changes.
g) Immunologic reaction; E.g. Hypersensitivity
reaction.
, Cell injury & Cellular Adaptive Changes
a) Physical agents
• Trauma, Burn, pressure, irradiation
b) Chemical agents; Poisons and drugs
c) Micro organisms- Bacteria, Virus, Fungus and
Parasites
d) Genetic defects; Can affect cellular metabolism
through inborn errors of metabolism or gross
malformation
, e) Hypoxia
• Is the most common stimuli (cause)
• Is because of inadequate oxygen in the blood
or decreased tissue Perfusion.
f) Nutritional imbalances ; Under nutrition or
over nutrition causes cellular injury or
changes.
g) Immunologic reaction; E.g. Hypersensitivity
reaction.
