PANCREATITIS
M S N 570: Advanced Pathophysiology
, CASE STUDY 13-year-old female
O V E RV I E W Signs & Symptoms:
• Sharp, persistent, non-radiating
epigastric pain (rated 6/10)
• Nausea/vomiting (several times
daily for 4 days)
• Diarrhea at first (twice)
• HR: 1 2 0 B P M
• Weight loss of 2 k g in 3 days
• Fatigue
• Delayed capillary refill
• Guarding and tenderness to
abdomen
Cierra Rangel
• Dehydration
, Secretio n: Function: Cell Type:
Glucag on 𝖳blood Alpha Cells
glucose level
(breakdown of
glycogen to
glucose)
Ins ulin blood Beta Cells
glucose level
(𝖳 uptake of
glucose into
cells & 𝖳
storage of
fats, carbs, &
proteins)
Amylin g lucag on, Beta Cells
delays gastric
emptying, 𝖳
satiety
Somatostatin s ecretion of Delta Cells
T H E PA N C R E A S
insulin,
glucagon, and
pancreatic
peptide
Gas trin 𝖳 Delta Cells
production/se
cretion of
Cierra Rangel digestive
enzymes &
bile
Pancreatic 𝖳
s ecretion of Pancreatic
Polypeptide gastric acid Polypeptide
Cells
Ghrelin “hunger Epsilon
Cells
M S N 570: Advanced Pathophysiology
, CASE STUDY 13-year-old female
O V E RV I E W Signs & Symptoms:
• Sharp, persistent, non-radiating
epigastric pain (rated 6/10)
• Nausea/vomiting (several times
daily for 4 days)
• Diarrhea at first (twice)
• HR: 1 2 0 B P M
• Weight loss of 2 k g in 3 days
• Fatigue
• Delayed capillary refill
• Guarding and tenderness to
abdomen
Cierra Rangel
• Dehydration
, Secretio n: Function: Cell Type:
Glucag on 𝖳blood Alpha Cells
glucose level
(breakdown of
glycogen to
glucose)
Ins ulin blood Beta Cells
glucose level
(𝖳 uptake of
glucose into
cells & 𝖳
storage of
fats, carbs, &
proteins)
Amylin g lucag on, Beta Cells
delays gastric
emptying, 𝖳
satiety
Somatostatin s ecretion of Delta Cells
T H E PA N C R E A S
insulin,
glucagon, and
pancreatic
peptide
Gas trin 𝖳 Delta Cells
production/se
cretion of
Cierra Rangel digestive
enzymes &
bile
Pancreatic 𝖳
s ecretion of Pancreatic
Polypeptide gastric acid Polypeptide
Cells
Ghrelin “hunger Epsilon
Cells
