ABSITE Questions And Answers All Are
Correct
The vagus nerve mediates what in the setting of systemic inflammation? Correct Answer: Enhanced
gut motility
What type of hormones are cytokines? Correct Answer: polypeptide
Function of heat shock proteins Correct Answer: Binding of autologous proteins to improve ligand
binding
Omega-3 fatty acids have what affect on the inflammatory response? Correct Answer: Decrease
What is a known affect of TNF? Correct Answer: Expression of eicosanoids (like thromboxane)
What is an adhesion molecule? Correct Answer: Mediate leukocyte to endothelial adhesion
What is an example of an adhesion molecule? Correct Answer: L-selectin
Physiologic affect of NO Correct Answer: Increase smooth muscle relaxation
Prostacyclin on systemic inflammation Correct Answer: Inhibits platelet aggregation
Calories per day for basal metabolism of healthy adult? Correct Answer: 20-25 kcal/kg/day
Source of calories during acute starvation? Correct Answer: fat
Source of calories for prolonged starvation? Correct Answer: Ketone bodies
Source of fuel after acute injury Correct Answer: fat
Sepsis increases metabolic needs by what % Correct Answer: 50%
Most abundant amino acid Correct Answer: glutamine
Pt with fever, tachycardia, and tachypnea, no localizing sx, no source. What do they have? Correct
Answer: SIRS
How long can elevated cortisol levels persist with a significant burn? Correct Answer: 1 month
What is used to mitigate cortisol affects on wound healing? Correct Answer: Vitamin A
Overfeeding critically ill patient can lead to? Correct Answer: Increased infection risk.
Initial enteral formula for surgical patients? Correct Answer: low-residual isotonic
Nutrient proportionally incrased in pulmonary failure enteral formula? Correct Answer: fat
,Vitamin not present in commercially prepared IV vitamin preparations and must be supplemented
with TPN? Correct Answer: Vitamin K
New onset of glucose intolerance in TPN dependent patient can be caused by? Correct Answer: zinc
deficiency
Potential physiologic affect of anabolism (positive N balance) Correct Answer: glucosuria
% body weight is water Correct Answer: 50-60%
What is the largest fluid compartment? Correct Answer: intracellular
% NS that goes to interstitial space? Correct Answer: 75%
Calculate serum osmolality: Na 130, Cl 94, K 5.2, CO2 14, Glucose 360, BUN 84, Cr 3.2 Correct
Answer: 310. Formula: Na x 2 + (BUN/2.8) + (Glucose/18)
Patient develops high output fistula after abd surgery. Fluid is sent: Na 135, K 5, Cl 70. What is the
most likely source of the fistula? Correct Answer: Pancreas
Most likely dx in patient with normovolemic hyponatremia? Correct Answer: SIADH
Patient admitted with glucose of 500 and Na of 151. What is best approximation of actual serum
sodium? Correct Answer: 158. 1.6 mEq/ L Na increase for every 100 mg/dL glucose over 100 mg/dL
Most likely dx in pt with serum Na of 152, urine Na of > 20 mEq/L, and urine osmolality of >
300mOsm/L? Correct Answer: Cushing's syndrome
What electrolyte abnormality can you get while on NSAIDS with renal insufficency? Correct Answer:
hyperkalemia
Electrolyte abnormality can cause decreased deep tendon reflexes? Correct Answer: hypokalemia
Early ECG change in hyperkalemia Correct Answer: peaked t waves
Post-op patient with K of 2.9 is given 1 mEq/kg replacement of KCl. Repeat test after replacement
show K is 3.0. Most likely dx? Correct Answer: hypomagnesemia
Actual serum calcium level in pt with albumin of 2.0 and calcium of 6.6? Correct Answer: 8.2.
Corrected Ca = [0.8 x (normal albumin - patient's albumin)] + serum Ca level
Cause of acute hypophosphatemia Correct Answer: refeeding syndrome
hypomagnesemia clinically resembles which of the following? Correct Answer: hypocalcemia
Pt obtunded, Na 130, Cl 105, K 3.2 HCO3 15. Most likely Dx? Correct Answer: GI losses
Best fluid choice for serum fluid loss? Correct Answer: LR
, First tx administered to patient with K of 6.3 and flattened P waves on EKG? Correct Answer: Insulin
and glucose
Shock following severe CO poisioning is what kind? Correct Answer: vasodilatory
IInsulin drips should be used to maintain sreum glucose in nondiabetic, critically ill patients at levels
between? Correct Answer: 80 - 110
62 yo man in MVA. Blunt trauma to sternum. Systolic bp of 95. CVP 15 CXR normal. Most likely
cause? Correct Answer: MI
Best way to prepare a type I von willebrand's dz for surgery? Correct Answer: Desmopressin
Hemophilia C is cause by? Correct Answer: Factor XI deficiency
Factor XIII deficiency most commonly presents as? Correct Answer: delayed bleeding after injury or
surgery
Bleeding patients with thrombasthenia is treated with? Correct Answer: platelet tx
Bleeding patinets with Bernard-soulier syndrome is treated with? Correct Answer: Platelet tx
Patient with albinism and bleeding disorder most likely has? Correct Answer: Dense granule
deficiency
First line therapy in an adult with idiopathic thrombocytopenia purpura includes? Correct Answer: IV
ig
HIT is made by? Correct Answer: Positive serotonin release assay
HIT patients should be treated with? Correct Answer: Lepirudin
Most effective tx for bleeding secondary to TTP is? Correct Answer: plasmapheresis
In a 70 kg patient, tx of 1 unit platelets should raise platelet count by? Correct Answer: 10,000
Patient with prolonged PTT and DVT should be evaluated for? Correct Answer: Antiphospholipid
syndrome
Increase the effect of warfarin? Correct Answer: Cephalosporins
Patient on warfarin with INR 1.4 presents with appendicitis. Management? Correct Answer: Proceed
with surgery, do not wait
Most effective device for hemostasis during thyroidectomy? Correct Answer: harmonic scalpel
Best topical agent to use in patients with coagulophathy? Correct Answer: Fibrin sealant
% of pop Rh- Correct Answer: 15
Correct
The vagus nerve mediates what in the setting of systemic inflammation? Correct Answer: Enhanced
gut motility
What type of hormones are cytokines? Correct Answer: polypeptide
Function of heat shock proteins Correct Answer: Binding of autologous proteins to improve ligand
binding
Omega-3 fatty acids have what affect on the inflammatory response? Correct Answer: Decrease
What is a known affect of TNF? Correct Answer: Expression of eicosanoids (like thromboxane)
What is an adhesion molecule? Correct Answer: Mediate leukocyte to endothelial adhesion
What is an example of an adhesion molecule? Correct Answer: L-selectin
Physiologic affect of NO Correct Answer: Increase smooth muscle relaxation
Prostacyclin on systemic inflammation Correct Answer: Inhibits platelet aggregation
Calories per day for basal metabolism of healthy adult? Correct Answer: 20-25 kcal/kg/day
Source of calories during acute starvation? Correct Answer: fat
Source of calories for prolonged starvation? Correct Answer: Ketone bodies
Source of fuel after acute injury Correct Answer: fat
Sepsis increases metabolic needs by what % Correct Answer: 50%
Most abundant amino acid Correct Answer: glutamine
Pt with fever, tachycardia, and tachypnea, no localizing sx, no source. What do they have? Correct
Answer: SIRS
How long can elevated cortisol levels persist with a significant burn? Correct Answer: 1 month
What is used to mitigate cortisol affects on wound healing? Correct Answer: Vitamin A
Overfeeding critically ill patient can lead to? Correct Answer: Increased infection risk.
Initial enteral formula for surgical patients? Correct Answer: low-residual isotonic
Nutrient proportionally incrased in pulmonary failure enteral formula? Correct Answer: fat
,Vitamin not present in commercially prepared IV vitamin preparations and must be supplemented
with TPN? Correct Answer: Vitamin K
New onset of glucose intolerance in TPN dependent patient can be caused by? Correct Answer: zinc
deficiency
Potential physiologic affect of anabolism (positive N balance) Correct Answer: glucosuria
% body weight is water Correct Answer: 50-60%
What is the largest fluid compartment? Correct Answer: intracellular
% NS that goes to interstitial space? Correct Answer: 75%
Calculate serum osmolality: Na 130, Cl 94, K 5.2, CO2 14, Glucose 360, BUN 84, Cr 3.2 Correct
Answer: 310. Formula: Na x 2 + (BUN/2.8) + (Glucose/18)
Patient develops high output fistula after abd surgery. Fluid is sent: Na 135, K 5, Cl 70. What is the
most likely source of the fistula? Correct Answer: Pancreas
Most likely dx in patient with normovolemic hyponatremia? Correct Answer: SIADH
Patient admitted with glucose of 500 and Na of 151. What is best approximation of actual serum
sodium? Correct Answer: 158. 1.6 mEq/ L Na increase for every 100 mg/dL glucose over 100 mg/dL
Most likely dx in pt with serum Na of 152, urine Na of > 20 mEq/L, and urine osmolality of >
300mOsm/L? Correct Answer: Cushing's syndrome
What electrolyte abnormality can you get while on NSAIDS with renal insufficency? Correct Answer:
hyperkalemia
Electrolyte abnormality can cause decreased deep tendon reflexes? Correct Answer: hypokalemia
Early ECG change in hyperkalemia Correct Answer: peaked t waves
Post-op patient with K of 2.9 is given 1 mEq/kg replacement of KCl. Repeat test after replacement
show K is 3.0. Most likely dx? Correct Answer: hypomagnesemia
Actual serum calcium level in pt with albumin of 2.0 and calcium of 6.6? Correct Answer: 8.2.
Corrected Ca = [0.8 x (normal albumin - patient's albumin)] + serum Ca level
Cause of acute hypophosphatemia Correct Answer: refeeding syndrome
hypomagnesemia clinically resembles which of the following? Correct Answer: hypocalcemia
Pt obtunded, Na 130, Cl 105, K 3.2 HCO3 15. Most likely Dx? Correct Answer: GI losses
Best fluid choice for serum fluid loss? Correct Answer: LR
, First tx administered to patient with K of 6.3 and flattened P waves on EKG? Correct Answer: Insulin
and glucose
Shock following severe CO poisioning is what kind? Correct Answer: vasodilatory
IInsulin drips should be used to maintain sreum glucose in nondiabetic, critically ill patients at levels
between? Correct Answer: 80 - 110
62 yo man in MVA. Blunt trauma to sternum. Systolic bp of 95. CVP 15 CXR normal. Most likely
cause? Correct Answer: MI
Best way to prepare a type I von willebrand's dz for surgery? Correct Answer: Desmopressin
Hemophilia C is cause by? Correct Answer: Factor XI deficiency
Factor XIII deficiency most commonly presents as? Correct Answer: delayed bleeding after injury or
surgery
Bleeding patients with thrombasthenia is treated with? Correct Answer: platelet tx
Bleeding patinets with Bernard-soulier syndrome is treated with? Correct Answer: Platelet tx
Patient with albinism and bleeding disorder most likely has? Correct Answer: Dense granule
deficiency
First line therapy in an adult with idiopathic thrombocytopenia purpura includes? Correct Answer: IV
ig
HIT is made by? Correct Answer: Positive serotonin release assay
HIT patients should be treated with? Correct Answer: Lepirudin
Most effective tx for bleeding secondary to TTP is? Correct Answer: plasmapheresis
In a 70 kg patient, tx of 1 unit platelets should raise platelet count by? Correct Answer: 10,000
Patient with prolonged PTT and DVT should be evaluated for? Correct Answer: Antiphospholipid
syndrome
Increase the effect of warfarin? Correct Answer: Cephalosporins
Patient on warfarin with INR 1.4 presents with appendicitis. Management? Correct Answer: Proceed
with surgery, do not wait
Most effective device for hemostasis during thyroidectomy? Correct Answer: harmonic scalpel
Best topical agent to use in patients with coagulophathy? Correct Answer: Fibrin sealant
% of pop Rh- Correct Answer: 15
