Multi Client
1. The healthcare provider ordered 500mg Vancomycin Hydrochloride IVPB every six
hours. The maximum safe dose range is 40mg/kg/day. The client weighs 165 lb. What is
the maximum therapeutic dose the nurse will administer per day? mg/day (If needed,
round to the nearest whole number)
3,000mg/day
2. What is the purpose of Vancomycin Hydrochloride and what are the
side effects/administration protocols?
Vancomycin Hydrochloride is an antibiotic.
Side effects include Ototoxicity (auditory portion of eighth cranial nerve).
Urogenital: Nephrotoxicity leading to uremia. Body as a Whole:Hypersensitivity
reactions (chills, fever, skin rash, urticaria, shock-like state), anaphylactoid
reaction with vascular collapse, superinfections, severe pain, thrombophlebitis at
injection site, generalized tingling following rapid IV infusion. Hematologic:
Transient leukopenia, eosinophilia. GI: Nausea, warmth. Other: Injection reaction
that includes hypotension accompanied by flushing and erythematous rash on
face and upper body ("red-neck syndrome") following rapid IV infusion.
Protocol Give a single dose at a rate of 10 mg/min or over NOT LESS than 60
min. Avoid rapid infusion, which may cause sudden hypotension. Monitor IV site
closely; necrosis and tissue sloughing will result from extravasation.
3. What are some of the risks that diabetics face as a result of uncontrolled
blood sugars?