Fat solubleYi
Introduction :
°
Angus &
coworkers isolated wit is in 1931 and named it
calciferol .
Vit is derived dehydro cholesterol
either
from Ergosterol
D
F
•
or
-
action radiations
by g Uv .
vitamin derived from fungus ergot
•
Commercially the is ,
-
°
Ergosterol →
Ergocalciferol ( Vit D2 )
UH
Some Hit D
imp
:
are
-
• .
resistant to heat oxidation acidic
Vit Ds
relatively and
'
o are
. ,
alkaline medium Thus not
easily destroyed while
cooking
.
.
Metabolism
#
of Vit D
Absorption :
Along with
lipids ,
vit D in
predominantly in
proximal
GIT .
Absorbed wit D enters circulation via
chylo microns .
Activation : Hit D vis hormone
pro
.
l
④ ④
l
( liver )
- -
kidney
25 -
hydroxylase t -
d -
hydroxylase Calcitniol
①
( la 25 -
Dihydnog
① ① i
@ cholecalciferol
(
Cholecalciferol ) ( 25 -
hydroxy cholecalciferol )
Introduction :
°
Angus &
coworkers isolated wit is in 1931 and named it
calciferol .
Vit is derived dehydro cholesterol
either
from Ergosterol
D
F
•
or
-
action radiations
by g Uv .
vitamin derived from fungus ergot
•
Commercially the is ,
-
°
Ergosterol →
Ergocalciferol ( Vit D2 )
UH
Some Hit D
imp
:
are
-
• .
resistant to heat oxidation acidic
Vit Ds
relatively and
'
o are
. ,
alkaline medium Thus not
easily destroyed while
cooking
.
.
Metabolism
#
of Vit D
Absorption :
Along with
lipids ,
vit D in
predominantly in
proximal
GIT .
Absorbed wit D enters circulation via
chylo microns .
Activation : Hit D vis hormone
pro
.
l
④ ④
l
( liver )
- -
kidney
25 -
hydroxylase t -
d -
hydroxylase Calcitniol
①
( la 25 -
Dihydnog
① ① i
@ cholecalciferol
(
Cholecalciferol ) ( 25 -
hydroxy cholecalciferol )
