Review) Questions And Answers
Gestational age criteria for PRETERM LABOR candidates receiving antenatal steroids? - All fetuses
between 24.0 and 34.6 weeks gestation at preterm risk within 7 days.
OR
Fetuses greater than 34 weeks w/ an immature lung profile
OR
If the mother is eligible for tocolytics
Gestational age criteria for preterm PROM candidates receiving antenatal steroids? - Less than 32.0
weeks gestation; in the absence of chorioamnionitis (Tx at 32-33 weeks may also be beneficial)
Antenatal corticosteroids are most effective when given within what time frame? - 24 hours and up to
7 days after administration of the second dose.
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significant reduction in infant mortality is still associated when <24hrs has passed so steroids should
always be given, if possible.
When can a rescue course of antenatal steroids be given? - If more than 2 weeks has passed since
last dose; fetus is <32.6; and likely to deliver w/in 7 days
Royal College of Obstetricians and Gynecologists advises that antenatal steroids should be given to
______. - All women for whom an elective c/s is planned prior to 38.6 weeks gestation.
Be tame those (Celestone) indications and dosage? - Indicated for reduction of neonatal mortality,
RDS, and IVH (intraventricular hemorrhage) in women at risk for preterm deliver less than 34 weeks
gestation.
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Dosage: 12mg IM q24h x2 doses
Dexamethasone (Decadron) indications and dosage? - Indicated for reduction of neonatal mortality,
RDS, and IVH (intraventricular hemorrhage) in women at risk for preterm deliver less than 34 weeks
gestation.
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Dosage: 6mg IM q12h x4 doses
17 alpha-hydroxyprogesterone caproate (Delalutin, Makena) (aka synthetic progestin) indications and
dosage? - Documented history of previous spontaneous singleton birth before 37 weeks gestation.
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Dosage: 200mg IM every week from 16 to 36 weeks gestation.
Progesterone (Progestin) indications and dosage? - In women with a singleton pregnancy, no hx for
preterm birth, and cervical length 20cm or less before 24 weeks.
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200mg vaginal suppository nightly until 36 weeks
OR
Vaginal progesterone gel 8% gel (90mg daily)