Oxford Cambridge and RSA
F
Monday 15 November 2021 – Morning
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/01 Biology (Foundation Tier)
Time allowed: 1 hour 45 minutes
* 8 3 4 7 8 9 0 5 9 4 *
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 6 0 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2021 [601/8690/2] OCR is an exempt Charity
DC (CE/CGW) 300860/5 Turn over
, 2
Answer all the questions.
1 Our bodies work constantly to keep our internal environment the same.
(a) What is this process called?
Tick (✓) one box.
Homeostasis
Homozygous
Homologous
Hormonal
[1]
(b) The human body maintains an internal temperature of around 37 °C.
Why is it important that this temperature is maintained?
Tick (✓) one box.
Enzymes in the human body only work at 37 °C.
Enzymes in the human body stop working at 37 °C.
Enzymes in the human body work best at 37 °C.
Enzymes in the human body work too quickly above 37 °C.
[1]
© OCR 2021
, 3
(c) Diabetes is a disease that affects our body’s ability to keep blood sugar concentration
constant. There are two main types of diabetes, Type 1 and Type 2.
Complete the table by deciding if each statement is correct for Type 1 diabetes only, Type 2
diabetes only or both types of diabetes.
Tick (✓) one box in each row.
Statement Type 1 Type 2 Both types of
diabetes only diabetes only diabetes
The body no longer responds to
insulin produced.
Treated using a combination of diet
and exercise.
Can be treated with insulin injections.
Diet should not contain too much
sugar.
The pancreas stops producing insulin.
[5]
(d) Complete the sentences to describe how insulin controls blood sugar level.
Put a ring around the correct answers.
Eating a sugary food increases / decreases blood sugar level.
The change in blood sugar level causes an increase / decrease in the amount of insulin
released from the pancreas.
The change in insulin level increases / decreases the absorption of blood sugar by cells.
[2]
© OCR 2021 Turn over
F
Monday 15 November 2021 – Morning
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/01 Biology (Foundation Tier)
Time allowed: 1 hour 45 minutes
* 8 3 4 7 8 9 0 5 9 4 *
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 6 0 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2021 [601/8690/2] OCR is an exempt Charity
DC (CE/CGW) 300860/5 Turn over
, 2
Answer all the questions.
1 Our bodies work constantly to keep our internal environment the same.
(a) What is this process called?
Tick (✓) one box.
Homeostasis
Homozygous
Homologous
Hormonal
[1]
(b) The human body maintains an internal temperature of around 37 °C.
Why is it important that this temperature is maintained?
Tick (✓) one box.
Enzymes in the human body only work at 37 °C.
Enzymes in the human body stop working at 37 °C.
Enzymes in the human body work best at 37 °C.
Enzymes in the human body work too quickly above 37 °C.
[1]
© OCR 2021
, 3
(c) Diabetes is a disease that affects our body’s ability to keep blood sugar concentration
constant. There are two main types of diabetes, Type 1 and Type 2.
Complete the table by deciding if each statement is correct for Type 1 diabetes only, Type 2
diabetes only or both types of diabetes.
Tick (✓) one box in each row.
Statement Type 1 Type 2 Both types of
diabetes only diabetes only diabetes
The body no longer responds to
insulin produced.
Treated using a combination of diet
and exercise.
Can be treated with insulin injections.
Diet should not contain too much
sugar.
The pancreas stops producing insulin.
[5]
(d) Complete the sentences to describe how insulin controls blood sugar level.
Put a ring around the correct answers.
Eating a sugary food increases / decreases blood sugar level.
The change in blood sugar level causes an increase / decrease in the amount of insulin
released from the pancreas.
The change in insulin level increases / decreases the absorption of blood sugar by cells.
[2]
© OCR 2021 Turn over
