A nurse plans care for a client with Cushing's disease. Which action should the nurse
include in this client's plan of care to prevent injury?
a. Pad the side rails of the client's bed.
b. Assist the client to change positions slowly.
c. Use a lift sheet to change the client's position.
d. Keep suctioning equipment at the clients bedside. - Answer C
Cushing's syndrome or disease greatly increases the serum levels of cortisol, which
contributes to excessive bone demineralization and increases the risk for pathologic
bone fracture. Padding the side rails and assisting the client to change position may be
effective, but these measures will not protect her as much as using a lift sheet. The
client should not require suctioning.
A nurse is caring for a client who was prescribed high-dose corticosteroid therapy for 1
month to treat a severe inflammatory condition. The client's symptoms have now
resolved and the client asks, "When can I stop taking these medications?" How should
the nurse respond?
a. It is possible for the inflammation to recur if you stop the medication.
b. Once you start corticosteroids, you have to be weaned off them.
c. You must decrease the dose slowly so your hormones will work again.
d. The drug suppresses your immune system, which must be built back up. - Answer B
One of the most common causes of adrenal insufficiency, a life-threatening problem, is
the sudden cessation of long-term, high-dose corticosteroid therapy. This therapy
suppresses the hypothalamic-pituitary-adrenal axis and must be withdrawn gradually to
allow for pituitary production of adrenocorticotropic hormone and adrenal production of
cortisol. Decreasing hormone therapy slowly ensures self-production of hormone, not
hormone effectiveness. Building the client's immune system and rebound inflammation
are not concerns related to stopping high-dose corticosteroids.
A nurse cares for a client with adrenal hyperfunction. The client screams at her
husband, bursts into tears, and throws her water pitcher against the wall. She then tells
the nurse, "I feel like I am going crazy." How should the nurse respond?
a. I will ask your doctor to order a psychiatric consult for you.
b. You feel this way because of your hormone levels.
c. Can I bring you information about support groups?
d. I will close the door to your room and restrict visitors. - Answer B
Hypercortisolism can cause the client to show neurotic or psychotic behavior. The client
needs to know that these behavior changes do not reflect a true psychiatric disorder
and will resolve when therapy results in lower and steadier blood cortisol levels. The
client needs to understand this effect and does not need a psychiatrist, support groups,
or restricted visitors at this time.
,A client with hyperaldosteronism is being treated with spironolactone (Aldactone) before
surgery. Which precautions does the nurse teach this client?
a. Read the label before using salt substitutes.
b. Do not add salt to your food when you eat.
c. Avoid exposure to sunlight.
d. Take Tylenol instead of aspirin for pain. - Answer A
Spironolactone is a potassium-sparing diuretic used to control potassium levels. Its use
can lead to hyperkalemia. Although the goal is to increase the client's potassium,
unknowingly adding potassium can cause complications. Some salt substitutes are
composed of potassium chloride and should be avoided by clients on spironolactone
therapy. Depending on the client, he or she may benefit from a low-sodium diet before
surgery, but this may not be necessary. Avoiding sunlight and Tylenol is not necessary.
A nurse cares for a client with chronic hypercortisolism. Which action should the nurse
take?
a. Wash hands when entering the room.
b. Keep the client in airborne isolation.
c. Observe the client for signs of infection.
d. Assess the client's daily chest x-ray. - Answer A
Excess cortisol reduces the number of circulating lymphocytes, inhibits maturation of
macrophages, reduces antibody synthesis, and inhibits production of cytokines and
inflammatory chemicals. As a result, these clients are at greater risk of infection and
may not have the expected inflammatory manifestations when an infection is present.
The nurse needs to take precautions to decrease the client's risk. It is not necessary to
keep the client in isolation. The client does not need a daily chest x-ray.
A nurse teaches a client with a cortisol deficiency who is prescribed prednisone
(Deltasone). Which statement should the nurse include in this client's instructions?
a. You will need to learn how to rotate the injection sites.
b. If you work outside in the heat, you may need another drug.
c. You need to follow a diet with strict sodium restrictions.
d. Take one tablet in the morning and two tablets at night. - Answer B
Steroid dosage adjustment may be needed if the client works outdoors and might be
difficult, especially in hot weather, when the client is sweating a great deal more than
normal. Clients take prednisone orally, have no need for a salt restriction, and usually
start the regimen with two tablets in the morning and one at night
An emergency nurse cares for a client who is experiencing an acute adrenal crisis.
Which action should the nurse take first?
a. Obtain intravenous access.
b. Administer hydrocortisone succinate (Solu-Cortef).
,c. Assess blood glucose.
d. Administer insulin and dextrose. - Answer A
All actions are appropriate for the client with adrenal crisis. However, therapy is given
intravenously, so the priority is to establish IV access. Solu-Cortef is the drug of choice.
Blood glucose is monitored hourly and treatment is provided as needed. Insulin and
dextrose are used to treat any hyperkalemia.
A nurse assesses a client who potentially has hyperaldosteronism. Which serum
laboratory values should the nurse associate with this disorder? (SATA)
a. Sodium: 150 mEq/L
b. Sodium: 130 mEq/L
c. Potassium: 2.5 mEq/L
d. Potassium: 5.0 mEq/L
e. pH: 7.28
f. pH: 7.50 - Answer ACF
Aldosterone increases reabsorption of sodium and excretion of potassium.
Hyperaldosteronism causes hypernatremia, hypokalemia, and metabolic alkalosis.
Hyponatremia, hyperkalemia, and acidosis are manifestations of adrenal insufficiency.
A nurse teaches a client with Cushing's disease. Which dietary requirements should the
nurse include in this client's teaching? (SATA)
a. Low calcium
b. Low carbohydrate
c. Low protein
d. Low calories
e. Low sodium - Answer BDE
The client with Cushing's disease has weight gain, muscle loss, hyperglycemia, and
sodium retention. Dietary modifications need to include reduction of carbohydrates and
total calories to prevent or reduce the degree of hyperglycemia. Sodium retention
causes water retention and hypertension. Clients are encouraged to restrict their
sodium intake moderately. Clients often have bone density loss and need more calcium.
Increased protein intake will help decrease muscle loss.
A nurse assesses clients with potential endocrine disorders. Which clients are at high
risk for adrenal insufficiency? (SATA)
a. A 22-year-old female with metastatic cancer
b. A 43-year-old male with tuberculosis
c. A 51-year-old female with asthma
d. A 65-year-old male with gram-negative sepsis
e. A 70-year-old female with hypertension - Answer ABD
Metastatic cancer, tuberculosis, and gram-negative sepsis are primary causes of
adrenal insufficiency. Active tuberculosis is a contributing factor for syndrome of
, inappropriate antidiuretic hormone. Hypertension is a key manifestation of Cushing's
disease. These are not risk factors for adrenal insufficiency.
A nurse assesses a client with Cushing's disease. Which assessment findings should
the nurse correlate with this disorder? (SATA)
a. Moon face
b. Weight loss
c. Hypotension
d. Petechiae
e. Muscle atrophy - Answer ADE
The nurse should monitor for increases in which laboratory value in a patient being
treated with dexamethasone?
a. Sodium
b. Calcium
c. Potassium
d. Blood glucose - Answer D
Hyperglycemia, or increased blood glucose level, is an adverse effect of corticosteroid
therapy. Sodium, calcium, and potassium levels are not affected directly by
dexamethasone.
A female patient who is on drug therapy for hyperaldosteronism develops menstrual
disorders. Which prescribed drug may be the cause of this condition?
a. Spironolactone
b. Amlodipine
c. Dexamethasone
d. Aminoglutethimide - Answer A
Spironolactone is a potassium-sparing diuretic given to patients with
hyperaldosteronism to treat hyperkalemia. This drug can cause menstrual disorders in
women. Amlodipine and dexamethasone both control high blood pressure.
Aminoglutethimide is given to decrease aldosterone synthesis.
A patient with adrenocortical insufficiency is prescribed hydrocortisone. Which drugs
should be avoided in the patient's prescription?
a. Oral contraceptives, antiepileptics, and nonsteroidal antiinflammatory drugs (NSAIDs)
b. Oral hypoglycemics, anticoagulants, and nonsteroidal antiinflammatory drugs
(NSAIDs)
c. Antihypertensives, oral hypoglycemics, and nonsteroidal antiinflammatory drugs
(NSAIDs)
d. Antiepileptics, antihypertensives, and oral hypoglycemics - Answer B
Hydrocortisone is a corticosteroid. Oral hypoglycemics, anticoagulants, and
nonsteroidal antiinflammatory drugs (NSAIDs) have potential interactions with