Exam (elaborations) PHARMACOLOGY, TOXICOLOGY/PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS Questions And Answers Updated Version

PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS 1. Two dose-response curve response plotted on the same graph showed sigmoid curves having the same slope and height. T curve is located to the right of the A curve. Which of the following statements is/are correct regarding curves A an: I. A is more effective than B II. A is more potent than B III. A and B have the same ceiling dose IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given with its non-competitive antagonist a. Only I and III are correct b. Only II, III and IV are correct c. Only II and IV are correct d. Only III and V are correct e. Only V is correct 2. Two dose-response curve plotted on the same graph showed sigmoid curves A and B, where A is at the left of the graph with the height greater than B. Which of the following statements is/are correct regarding curves A and B? I. A and B has equal efficacy II. A and B have equal potency III. B is a partial agonist of A IV. B is the graph produced when A is given with its competitive antagonist V. B is the graph produced when A is given with its non-competitive antagonist a. Only I and III are correct b. Only II, III and IV are correct c. Only II and IV are correct d. Only III and V are correct e. Only V is correct 3. The cumulative number of subjects who display a certain rersponse or effect to a drug is plotted on a graph as shown below. The graph on the left represents beneficial effect while the graph on the right represents toxic effect, what is the therapeutic index of the drug?