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1 MAJOR functions of the kidneys include
a Secretion of ADH
\ Filtration of urine into Bowman's Space
tl Regulation of extracellular fluid composition and volume
: Excretion of excess CCK and secretin
2 The glomerulus of every nephron
a ls dispensible (unnecessary) for renal function
lhh ls located in the renal cortex
* ls responsible for reabsorbing most of the water
d ls the final point in the nephron before renal filtrate becomes urine
3 Severe blood loss or dehydration producing in a drop in renal blood flow results in
and
i rl, Decreased GFR, activation of the renin-angiotensin-aldosterone system
h Decreased GFR, activation of ANP release
c lncreased GFRidecreased water reabsorption
d No change in GFR, reversal of flow through the Loop of Henle
4 For any solute entering the glomerular capillary bed, the amount of it that ends up being excreted
in urine is equalto
a The amount filtered plus the amount reabsorbed minus the amount secreted
ir The amount filtered minus the amount secreted plus the amount reabsorbed
i'*i\, lfre amount filtered minus the amount reabsorbed plus the amount secreted
d The amount filtered minus the mount reabsorbed minus the amount secreted
5 Glomerular filtration normally produces a filtrate that is
a Similar in composition to urine, except with more blood cells present
il Similar in composition to plasma, except with little or no protein
c Little different from what will eventually become urine
d So high in water that reabsorption of water via active transport is the only way to prevent
dehydration
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tJ*rsion 4
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6 Tubuloglomerular feedback is
a" The major determinant of whether protein is restricted from glomerular filtration
* Belatively unimportant for control of glomerular filtration
c A result of renin release
tj ls a negative feedback mechanism serving as the major means of autoregulatory control of
renal blood flow and glomerular filtration rate
7 Renal clearance of glucose is measured in a patient in the clinic The relevant data are:
Glucose concentration in plasma = 2000 mgll
Glucose concentration in urine = 1000 mg/L
Urine volume (2 h$ = 2 L = 2U2hr = 1 Uhr
. What is the clearance of glucose, and what does this suggest about this patient?
'ai 0.5 L/hr, this patient is normal
)' il
b 0.5 mg/hr, this patient is in heart failure r
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' e 0.5 L/hr, this patient may have diabetes 1
d 2Llhr, this patient pees way too much
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8 Most ol the water and sodium that are filtered at the glomerulus are
a Also secreted in the Loop of Henle
(.fl Reabsorbed in the proximal convoluted tubule
c Reabsorbed in the thick limb of the ascending Loop of Henle
d Reabsorbed in response to atrial natriuretic peptide (ANp)
I Biff eats an entire cup of table salt, with no water. What is the result of this stunt?
*a- Biff's ADH levels fall to almost nothing and he urinates excessive amounts of water
f.$ Aitt's ADH levels increase and his urine is highly concentrated with respect to sodium
c Biff's ADH levels increase, but he excretes a high volume, dilute urine
\.. .giff gets a call rom Johnny Knoxville offering a spot in the next Jackass movie.
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10 The main site of action of ADH is
i\
The hypothalamus
'*
The posterior pituitary
.: The distal convoluted tubule
( i-', The medullary collecting duct
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