PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS
1. Two dose-response curve response plotted on the same graph showed sigmoid
curves having the same slope and height. T curve is located to the right of the A
curve. Which of the following statements is/are correct regarding curves A an:
I. A is more effective than B
II. A is more potent than B
III. A and B have the same ceiling dose
IV. B is the graph produced when A is given with its competitive antagonist
V. B is the graph produced when A is given with its non-competitive
antagonist
a. Only I and III are correct
b. Only II, III and IV are correct
c. Only II and IV are correct
d. Only III and V are correct
e. Only V is correct
2. Two dose-response curve plotted on the same graph showed sigmoid curves A and
B, where A is at the left of the graph with the height greater than B. Which of the
following statements is/are correct regarding curves A and B?
I. A and B has equal efficacy
II. A and B have equal potency
III. B is a partial agonist of A
,PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
IV. B is the graph produced when A is given with its competitive antagonist
V. B is the graph produced when A is given with its non-competitive
antagonist
,PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
a. Only I and III are correct
b. Only II, III and IV are correct
c. Only II and IV are correct
d. Only III and V are correct
e. Only V is correct
3. The cumulative number of subjects who display a certain rersponse or effect to a
drug is plotted on a graph as shown below. The graph on the left represents
beneficial effect while the graph on the right represents toxic effect, what is the
therapeutic index of the drug?
a.0.5 b. 1.5 c. 2.5 d.4.0
e. 5.0
4. An administration of one drug leads to a shift in the log dose-response curve of
another drug to the left a range in the maximal efficacy, this is called
a. Agonism
b. Partial agonism
c. Non-competitive antagonism
d. Competitive antagonism
e. Potentiation
5. The action of this drug is dependent on a colligative property
a. Mannitol
b. Cocaine
c. Reserpine
d. Furosemide
e. Losartan
6. Whiich of the following drug groups have mechanisms of aaction that involve
binding to enzymes as target protiens
a. Benzodiazepines
b. Barbiturates
c. Calcium channel blockers
d. Non-steroidal anti-inflammatory agents
e. Phenothiazine antipsychotics
7. Voltage-gated ion channels serve as site of actions for drugs such as
I. Diltiazem and Nifedipine
II. Lidocaine and Procaine
III. Captopril and Losartan
a. I only
, PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
b. I and II
and answers
PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS
1. Two dose-response curve response plotted on the same graph showed sigmoid
curves having the same slope and height. T curve is located to the right of the A
curve. Which of the following statements is/are correct regarding curves A an:
I. A is more effective than B
II. A is more potent than B
III. A and B have the same ceiling dose
IV. B is the graph produced when A is given with its competitive antagonist
V. B is the graph produced when A is given with its non-competitive
antagonist
a. Only I and III are correct
b. Only II, III and IV are correct
c. Only II and IV are correct
d. Only III and V are correct
e. Only V is correct
2. Two dose-response curve plotted on the same graph showed sigmoid curves A and
B, where A is at the left of the graph with the height greater than B. Which of the
following statements is/are correct regarding curves A and B?
I. A and B has equal efficacy
II. A and B have equal potency
III. B is a partial agonist of A
,PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
IV. B is the graph produced when A is given with its competitive antagonist
V. B is the graph produced when A is given with its non-competitive
antagonist
,PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
a. Only I and III are correct
b. Only II, III and IV are correct
c. Only II and IV are correct
d. Only III and V are correct
e. Only V is correct
3. The cumulative number of subjects who display a certain rersponse or effect to a
drug is plotted on a graph as shown below. The graph on the left represents
beneficial effect while the graph on the right represents toxic effect, what is the
therapeutic index of the drug?
a.0.5 b. 1.5 c. 2.5 d.4.0
e. 5.0
4. An administration of one drug leads to a shift in the log dose-response curve of
another drug to the left a range in the maximal efficacy, this is called
a. Agonism
b. Partial agonism
c. Non-competitive antagonism
d. Competitive antagonism
e. Potentiation
5. The action of this drug is dependent on a colligative property
a. Mannitol
b. Cocaine
c. Reserpine
d. Furosemide
e. Losartan
6. Whiich of the following drug groups have mechanisms of aaction that involve
binding to enzymes as target protiens
a. Benzodiazepines
b. Barbiturates
c. Calcium channel blockers
d. Non-steroidal anti-inflammatory agents
e. Phenothiazine antipsychotics
7. Voltage-gated ion channels serve as site of actions for drugs such as
I. Diltiazem and Nifedipine
II. Lidocaine and Procaine
III. Captopril and Losartan
a. I only
, PHARMACOLOGY, TOXICOLOGY, PHARMACOKINETICS questions
and answers
b. I and II
