WGU C785 BIOCHEMISTRY PRE-ASSESSMENT (PA) LATEST UPDATE
2022/2023(DETAILED QUESTIONS AND ANSWERS)
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide insertion immediately
following the three guanines that encode for glycine 116? (correct answers)Thr
Acetylcholine is broken down to acetate and choline by an enzyme called acetylcholinesterase. Low
levels of acetylcholine in the brain is associated with neurodegenerative disease. Which of the following
medications could be used to treat neurodegeneration associated with low acetylcholine levels? (correct
answers)A non-competitive inhibitor of acetylcholinesterase.
An active elderly patient is becoming frequently disoriented, having trouble recalling her daily routine,
and becoming aggravated easily. She forgets words and places and has difficulty recognizing her
children.
Which biochemical event is responsible for this patient's behavior? (correct answers)Protein aggregation
An inhibitor is added to the following hypothetical pathway, which results in an accumulation of
compound C.
Which enzyme is affected by the inhibitor? (correct answers)enzyme 3
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? (correct answers)16
, Given the following amino acid structure, what is the strongest intermolecular force it would participate
in to stabilize a protein structure? (correct answers)hydrogen bond
Given the following amino acid structure, what is the strongest intermolecular force it would participate
in to stabilize a protein structure? (correct answers)Hydrogen bond
How do the rates of enzyme-catalyzed reactions compare to those of corresponding uncatalyzed
reactions? (correct answers)They are 10 6 to 10 12 times faster.
How does hemoglobin keep blood pH neutral during exercise? (correct answers)Deoxygenated
hemoglobin binds to excess H +.
How does insulin impact carbohydrate metabolism? (correct answers)It stimulates the uptake of glucose
from the blood by cells in the body.
How many ATP molecules are used in the conversion of pyruvate to glucose? (correct answers)6
How would lipid production in a cell change in order to maintain fluidity of its cell membrane as it
adapts to lower temperatures? (correct answers)Produce lipids with shorter fatty acid chains.
Identify the factors that favor the oxygenated form of hemoglobin. (correct answers)High pH, low
carbon dioxide
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
What change in codons corresponds to this mutation? (correct answers)GAA to GTA
In which situation would altering a protein structure lead to a disease state? (correct answers)A
mutation in aconitase blocks an essential step in aerobic metabolism
2022/2023(DETAILED QUESTIONS AND ANSWERS)
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide insertion immediately
following the three guanines that encode for glycine 116? (correct answers)Thr
Acetylcholine is broken down to acetate and choline by an enzyme called acetylcholinesterase. Low
levels of acetylcholine in the brain is associated with neurodegenerative disease. Which of the following
medications could be used to treat neurodegeneration associated with low acetylcholine levels? (correct
answers)A non-competitive inhibitor of acetylcholinesterase.
An active elderly patient is becoming frequently disoriented, having trouble recalling her daily routine,
and becoming aggravated easily. She forgets words and places and has difficulty recognizing her
children.
Which biochemical event is responsible for this patient's behavior? (correct answers)Protein aggregation
An inhibitor is added to the following hypothetical pathway, which results in an accumulation of
compound C.
Which enzyme is affected by the inhibitor? (correct answers)enzyme 3
Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four
complete PCR cycles? (correct answers)16
, Given the following amino acid structure, what is the strongest intermolecular force it would participate
in to stabilize a protein structure? (correct answers)hydrogen bond
Given the following amino acid structure, what is the strongest intermolecular force it would participate
in to stabilize a protein structure? (correct answers)Hydrogen bond
How do the rates of enzyme-catalyzed reactions compare to those of corresponding uncatalyzed
reactions? (correct answers)They are 10 6 to 10 12 times faster.
How does hemoglobin keep blood pH neutral during exercise? (correct answers)Deoxygenated
hemoglobin binds to excess H +.
How does insulin impact carbohydrate metabolism? (correct answers)It stimulates the uptake of glucose
from the blood by cells in the body.
How many ATP molecules are used in the conversion of pyruvate to glucose? (correct answers)6
How would lipid production in a cell change in order to maintain fluidity of its cell membrane as it
adapts to lower temperatures? (correct answers)Produce lipids with shorter fatty acid chains.
Identify the factors that favor the oxygenated form of hemoglobin. (correct answers)High pH, low
carbon dioxide
In sickle-cell disease, the glutamic acid (Glu) at position number seven is mutated to valine (Val).
What change in codons corresponds to this mutation? (correct answers)GAA to GTA
In which situation would altering a protein structure lead to a disease state? (correct answers)A
mutation in aconitase blocks an essential step in aerobic metabolism
