ATI Pharm Proctored Exam
Aspirin - NSAID
Reye Syndrome in kids
Toxicity=salicylism (tinnitus, seizures, hyperventilation, tetany, naseua, vomiting)
Ibuprofen - NSAID
increases lithium levels
Acetaminophen - Not an NSAID
doesn't affect blood coagulation
Antidote: acetycysteine
Indomethacin - Strong NSAID
OA, RA, acute gout attacks
Celecoxib - NSAID
OA, RA, dysmenorrhea
Morphine - PCA
opiod agonist
10-15 min onset
DOC for chest pain
AE: Resp depression
Antidote: Naloxone
Naloxone - opiod antagonist
reverses analgesia (increased R, HR, BP)
Used in heroin OD
Sumatriptan - Tx of migraines
Abortive
AE: angina
Ergotamine - Tx of headaches
Abortive
AE: ergotism (muscle spasm, wkns, cold)
Pregnancy X
Allopurinol - Antigout
Prophylactic
Increase fluid intake
Avoid foods high in uric acid
Colchicine - Antigout
, Abortive (decreases inflamm and pain)
AE: bone marrow suppression, paralytic ileus
Codeine - antitussive
Fentanyl - transdermal patch
stronger than morphine
Hydrocodone/Oxycodone - Risk for respiratory depression with acetaminophen
Frequently abused
Methadone - Antidote for codeine
Hydromorphone - used when morphine doesn't work
Acetylcysteine - Mucolytic
Liquifies secretions
Antidote for acetaminophen OD
Albuterol - Bronchodilator
Abortive
Rescue drug for asthma
AE: tachycardia, anxiety, tremors
Ipratropim Bromide (Atrovent) - Anticholinergic=dry
inhibits mucus secretion and bronchoconstriction
Not abortive
Theophylline - bronchodilator
5-15mcg therapeutic range
BBW: needs slow infusion
AE: tachycardia, urinary frequency, insomnia, diarrhea, tremors
Montelukast - Tx of chronic asthma
Not abortive (take daily in evening)
Prevents hypersecretion and bronchoconstriction
Drug for exercise induced asthma
Cromolyn Sodium - inhibit mast cell rupture (prevents bronchoconstriction)
Not abortive
Take prior to rescue or allergen CI with lactose (milk)
Digoxin - Increases force of contraction
Decreases HR
Decreases conduction
S/S of Toxicity: visual disturbances, N/V, fatigue, yellow skin, anorexia
Aspirin - NSAID
Reye Syndrome in kids
Toxicity=salicylism (tinnitus, seizures, hyperventilation, tetany, naseua, vomiting)
Ibuprofen - NSAID
increases lithium levels
Acetaminophen - Not an NSAID
doesn't affect blood coagulation
Antidote: acetycysteine
Indomethacin - Strong NSAID
OA, RA, acute gout attacks
Celecoxib - NSAID
OA, RA, dysmenorrhea
Morphine - PCA
opiod agonist
10-15 min onset
DOC for chest pain
AE: Resp depression
Antidote: Naloxone
Naloxone - opiod antagonist
reverses analgesia (increased R, HR, BP)
Used in heroin OD
Sumatriptan - Tx of migraines
Abortive
AE: angina
Ergotamine - Tx of headaches
Abortive
AE: ergotism (muscle spasm, wkns, cold)
Pregnancy X
Allopurinol - Antigout
Prophylactic
Increase fluid intake
Avoid foods high in uric acid
Colchicine - Antigout
, Abortive (decreases inflamm and pain)
AE: bone marrow suppression, paralytic ileus
Codeine - antitussive
Fentanyl - transdermal patch
stronger than morphine
Hydrocodone/Oxycodone - Risk for respiratory depression with acetaminophen
Frequently abused
Methadone - Antidote for codeine
Hydromorphone - used when morphine doesn't work
Acetylcysteine - Mucolytic
Liquifies secretions
Antidote for acetaminophen OD
Albuterol - Bronchodilator
Abortive
Rescue drug for asthma
AE: tachycardia, anxiety, tremors
Ipratropim Bromide (Atrovent) - Anticholinergic=dry
inhibits mucus secretion and bronchoconstriction
Not abortive
Theophylline - bronchodilator
5-15mcg therapeutic range
BBW: needs slow infusion
AE: tachycardia, urinary frequency, insomnia, diarrhea, tremors
Montelukast - Tx of chronic asthma
Not abortive (take daily in evening)
Prevents hypersecretion and bronchoconstriction
Drug for exercise induced asthma
Cromolyn Sodium - inhibit mast cell rupture (prevents bronchoconstriction)
Not abortive
Take prior to rescue or allergen CI with lactose (milk)
Digoxin - Increases force of contraction
Decreases HR
Decreases conduction
S/S of Toxicity: visual disturbances, N/V, fatigue, yellow skin, anorexia