U-WORLD
RATIONALES
,Hematological/Oncological
Monoclonal antibodies
Test Id: 91134314
QId: 34074 (1051007)
1 of 75
A A A
0
A nurse is administering a rituximab infusion to a client with lymphoma in an oncology
clinic. Which client symptom would be a priority to report to the health care provider?
Dizziness and sudden diarrhea [1%]
1.
Nausea and onset of vomiting [0%]
2.
New-onset tachypnea and dyspnea [81%]
3.
Temperature of 101 F (38.3 C) [17%]
4.
, Correct
Answered correctly
81%
Time: 12 seconds
Updated: 10/14/2017
Explanation:
Rituximab (Rituxan) is a monoclonal antibody (end in -mab) that affects the lymphocytes.
It is commonly prescribed to treat certain forms of cancer (eg, lymphoma) and autoimmune
diseases (eg, lupus). Like many monoclonal antibodies, rituximab can produce a powerful
immune response (eg, bronchospasm, dyspnea, tachypnea, hypotension,
angioedema) (Option 3). The nurse should closely monitor the client during and after the
infusion. If life-threatening symptoms develop, the nurse should stop the infusion and
immediately notify the health care provider. The symptoms will be treated (eg,
corticosteroids) and, when resolved, the infusion is usually restarted at a slower rate.
(Options 1, 2, and 4) In many clients, monoclonal antibody therapies, like many oncology
pharmaceuticals, invoke flu-like responses (eg, fever, chills, diarrhea, nausea, vomiting).
Clients are often pretreated with acetaminophen and diphenhydramine in anticipation of these
reactions. Clients' symptoms are treated as needed (eg, antiemetics, antidiarrheals).
Educational objective:
Rituximab can produce a powerful immune response (eg, bronchospasm, dyspnea, tachypnea,
hypotension, angioedema). Clients should be closely monitored during and after the infusion.
Copyright © UWorld. All rights reserved.
Basic Care & Comfort/Pain Management
Culture / Spirituality
Test Id: 91134314
QId: 34722 (1051007)
, 2 of 75
A A A
0
The student nurse plans postmortem care for an Orthodox Jewish client hospitalized for the
last week with heart failure who did not sign consents for any postmortem actions. Which
statement by the student would require further education by the supervising nurse?
"I will allow the family to remain with the client at all times." [3%]
1.
"I will call the next of kin before providing any postmortem care." [7%]
2.
"I will prepare the client for transfer to the morgue for autopsy." [81%]
3.
"I will provide a sheet to be placed over the client's face." [7%]
4.
RATIONALES
,Hematological/Oncological
Monoclonal antibodies
Test Id: 91134314
QId: 34074 (1051007)
1 of 75
A A A
0
A nurse is administering a rituximab infusion to a client with lymphoma in an oncology
clinic. Which client symptom would be a priority to report to the health care provider?
Dizziness and sudden diarrhea [1%]
1.
Nausea and onset of vomiting [0%]
2.
New-onset tachypnea and dyspnea [81%]
3.
Temperature of 101 F (38.3 C) [17%]
4.
, Correct
Answered correctly
81%
Time: 12 seconds
Updated: 10/14/2017
Explanation:
Rituximab (Rituxan) is a monoclonal antibody (end in -mab) that affects the lymphocytes.
It is commonly prescribed to treat certain forms of cancer (eg, lymphoma) and autoimmune
diseases (eg, lupus). Like many monoclonal antibodies, rituximab can produce a powerful
immune response (eg, bronchospasm, dyspnea, tachypnea, hypotension,
angioedema) (Option 3). The nurse should closely monitor the client during and after the
infusion. If life-threatening symptoms develop, the nurse should stop the infusion and
immediately notify the health care provider. The symptoms will be treated (eg,
corticosteroids) and, when resolved, the infusion is usually restarted at a slower rate.
(Options 1, 2, and 4) In many clients, monoclonal antibody therapies, like many oncology
pharmaceuticals, invoke flu-like responses (eg, fever, chills, diarrhea, nausea, vomiting).
Clients are often pretreated with acetaminophen and diphenhydramine in anticipation of these
reactions. Clients' symptoms are treated as needed (eg, antiemetics, antidiarrheals).
Educational objective:
Rituximab can produce a powerful immune response (eg, bronchospasm, dyspnea, tachypnea,
hypotension, angioedema). Clients should be closely monitored during and after the infusion.
Copyright © UWorld. All rights reserved.
Basic Care & Comfort/Pain Management
Culture / Spirituality
Test Id: 91134314
QId: 34722 (1051007)
, 2 of 75
A A A
0
The student nurse plans postmortem care for an Orthodox Jewish client hospitalized for the
last week with heart failure who did not sign consents for any postmortem actions. Which
statement by the student would require further education by the supervising nurse?
"I will allow the family to remain with the client at all times." [3%]
1.
"I will call the next of kin before providing any postmortem care." [7%]
2.
"I will prepare the client for transfer to the morgue for autopsy." [81%]
3.
"I will provide a sheet to be placed over the client's face." [7%]
4.
