Animal Physiology,Third EditionHill • Wyse • Anderson Chapter 8: Aerobic and Anaerobic Forms of Metabolism

1. Glycolysis occurs in the _______ and generates _______ NADH molecules. a. cytosol; 4 b. cytosol; 2 c. mitochondria; 2 d. mitochondria; 4 e. nucleus; 2 Answer: b Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 184 Bloom’s Category: 1. Remembering 2. The enzyme _______ is needed to convert phosphoenolpyruvic acid to pyruvic acid. a. hexokinase b. phosphofructokinase c. glyceraldehyde-3-phosphate dehydrogenase d. enolase e. pyruvate kinase Answer: e Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 184 Bloom’s Category: 1. Remembering 3. The substrate _______ is required for glycolysis to begin. a. pyruvate b. glycol c. glucose d. acetyl coenzyme A e. NADH2 Answer: c Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 184 Bloom’s Category: 1. Remembering 4. The enzyme _______ is required to convert glucose to glucose-6-phosphate. a. hexokinase b. phosphofructokinase c. enolase d. pyruvate kinase e. isomerase Answer: a © 2012 Sinauer Associates, Inc. Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 184 Bloom’s Category: 1. Remembering 5. The reaction that uses _______ as a substrate is an oxidation reaction in glycolysis. a. glucose b. fructose-1,6-diphosphate c. 2-phosphoglyceric acid d. glyceraldehyde-3-phosphate e. dihydroxyacetone phosphate Answer: d Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 1. Remembering 6. The substrate needed to initiate the Krebs cycle is a. pyruvate. b. glucose. c. acetyl coenzyme A. d. citrate. e. ATP. Answer: c Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 2. Understanding 7. Which of the following molecules is (are) generated during aerobic metabolism? a. CO2 b. H2O c. Lactic acid d. CO2 and lactic acid e. CO2 and H2O Answer: e Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 2. Understanding 8. Which of the following chemical reactions of the Krebs cycle produces FADH2? a. Succinate  fumarate b. Citrate  isocitrate c. Fumarate  malate d. Isocitrate  -ketoglutarate e. Succinyl coenzyme A  succinate Answer: a Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 1. Remembering 9. Which of the following chemical reactions of the Krebs cycle produces NADH? a. Citrate  isocitrate b. Succinate  fumarate © 2012 Sinauer Associates, Inc. c. Fumarate  malate d. Isocitrate  -ketoglutarate e. Succinyl coenzyme A  succinate Answer: d Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 1. Remembering 10. Which of the following chemical reactions of the Krebs cycle produces GTP? a. Citrate  isocitrate b. Succinate  fumarate c. Fumarate  malate d. Isocitrate  -ketoglutarate e. Succinyl coenzyme A  succinate Answer: e Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 185 Bloom’s Category: 1. Remembering 11. The specific role of oxygen in the cell is to a. power glycolysis. b. enhance the production of NADH in glycolysis. c. promote oxidation of FADH2. d. act as an energy source for ATP production. e. act as a final electron acceptor. Answer: e Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 186 Bloom’s Category: 1. Remembering 12. What effect would consumption of cyanide have on an animal? a. Glycolysis would shut down b. The Krebs cycle would accelerate c. The electron transport chain would be halted d. NADH recycling to NAD+ will not be affected e. FADH2 recycling will be affected slightly but not entirely Answer: c Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 186 Bloom’s Category: 4. Analyzing 13. Which of the following molecules oxidizes FADH2? a. NADH-Q oxidoreductase b. Succinate dehydrogenase c. Cytochrome b-c1 d. Cytochrome oxidase e. ATP synthase Answer: b Textbook Reference: Mechanisms of ATP Production and Their Implications, p. 186 © 2012 Sinauer Associates, Inc. Bloom’s Category: 1. Remembering 14. Which of the following molecules does n