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HEMOSTASIS-PHYSIOLOGY

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HEMOSTASIS-PHYSIOLOGY

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HEMOSTASIS
DEFINITION;hemostasis is the a process to prevent bleeding

Stages of hemostasis
 Vaso constriction
 Platelet plug formation
 Coagulation of blood


Factors involved in blood clotting

Factor I Fibrinogen



Factor II Prothrombin



Factor III Thromboplastin



Factor IV Calcium



Factor V Labile factor (proaccelerin)



Factor VI Presence has not been proved



Factor VII Stable factor or Proconvertin or
serum prothrombin conversion
accelerator (SPCA)

, Factor VIII Antihemophilic factor A
(Antihemophilic globulin


Factor IX Antihemophilic factor B or Christmas
factor (PTC)


Factor X Stuart prower factor (Auto
Prothrombin III)



Factor XI Plasma thromboplastin antecedent
(PTA)


Factor XII Hageman factor (Surface or glass
contact factor)

Fibrino stabilizing factor (Laki-Lorand
Factor XIII
factor)



Stages of Coagulation

Stage 1 Inactive procoagulants become active and finally there is formation of
prothrombin activator

Stage 2 Conversion of prothrombin into thrombin




Stage 3 Conversion of fibrinogen into fibrin

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