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MN 553 Advanced Pharmacology Final Exam

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Question options: 4oF (40.5oC) after previous DTaP vaccine of seizures after DTaP vaccine egnancy A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to: Question options: ient will not have increased adverse drug reactions to the tamoxifen tial drug-drug interactions that may occur with tamoxifen metabolizers of tamoxifen Several classes of drugs have interactions with cholinergic blockers. Which of the following is true about these interactions? Question options: muscarinic effects may occur with antihistamines. lockers may decrease the sedative effects of hypnotics. lockers are contraindicated with antipsychotics. Absolute contraindications that clinicians must consider when initiating estrogen therapy include: Question options: dysfunctional uterine bleeding arterial thromboemboli within the prior year s ove First-line therapy for treating topical fungal infections such as tinea corporis (ringworm) or tinea pedis (athlete’s foot) would be: Question options: ine lvin microsize m or ointment Preventative therapy for cluster headaches includes: Question options: elaxation therapy ocaine four times a day during “clusters” of headaches Inderal) daily Why is the consistency of taking paroxetine (Paxil) and never running out of medication more important than with most other selective serotonin reuptake inhibitors (SSRIs)? Question options: gest half-life and the withdrawal syndrome has a faster onset. dictive in the dopaminergic reward system. activating of SSRI medications and will cause the person to have sudden deep sadness. Sook has been prescribed gabapentin to treat neuropathic pain and is complaining of feeling depressed and having “strange” thoughts. The appropriate initial action would be: Question options: dose he medication immediately dose to half then slowly titrate up the dose The drug of choice for type 2 diabetics is metformin. Metformin: Question options: release of insulin from beta cells stinal uptake of glucose ght gain associated with hyperglycemia Gender differences between men and women in pharmacokinetics include: Question options: astric emptying so that drugs absorbed in the stomach have less exposure to absorption sites rtion of body fat so that lipophilic drugs have relatively greater volumes of distribution els of bile acids so that drugs metabolized in the intestine have higher concentrations blood flow rates so drugs tend to take longer to be excreted Lisa is a healthy nonpregnant adult woman who recently had a urinary tract infection (UTI). She is asking about drinking cranberry juice to prevent a recurrence of the UTI. The correct answer to give her would be: Question options: es per day of cranberry juice cocktail will prevent UTIs. rry juice or cranberry juice extract may decrease UTIs in some patients. vidence that cranberry juice helps prevent UTIs. ce only works to prevent UTIs in children. ACE inhibitors are contraindicated in pregnancy. While treatment of heart failure during pregnancy is best done by a specialist, which of the following drug classes is considered to be safe, at least in the later parts of pregnancy? Question options: s Which of the following holds true for the pharmacokinetics of women? Question options: ying is faster than

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MN 553 Advanced Pharmacology Final Exam

points
Jim is being treated for hypertension. Because he has a history
of heart attack, the drug chosen is atenolol. Beta blockers
treat hypertension by:
Question options:
rt rate to improve cardiac output
ular smooth muscle tone
osterone-mediated volume activity
ous humor production


Opiates are used mainly to treat moderate to severe pain.
Which of the following is NOT true about these drugs?
Question options:
scheduled drugs which require a DEA license to prescribe.
ate only mu receptors for the control of pain.
verse effects of opiates are related to mu receptor stimulation.
antagonist to opiates.


When considering which cholesterol-lowering drug to
prescribe, which factor determines the type and intensity of
treatment?
Question options:


y disease risk level
holesterol


Being competent in the use of information technology in
clinical practice is expected in professional nurses. Advanced
practice competence includes the ability to:
Question options:

, rmation using the most common search engines
nt experts in developing, implementing, and evaluating information Systems
s to assure the integrity of health information
on technology to prescribe drugs


The New York Heart Association and the Canadian
Cardiovascular Society have described grading criteria for
levels of angina. Angina that occurs with unusually strenuous
activity or on walking or climbing stair after meals is class:
Question options:




An Investigational New Drug is filed with the U.S. Food and
Drug Administration:
Question options:
ufacturer has completed phase III trials
rug is discovered
l testing of any new drug entity
testing of any new drug entity



True contraindications to diphtheria, tetanus, and acellular
pertussis (DTaP or Tdap) vaccine include:
Question options:
4oF (40.5oC) after previous DTaP
vaccine of seizures after DTaP vaccine
egnancy
eaction with a previous dose



A provider may consider testing for CYP2D6 variants prior to
starting tamoxifen for breast cancer to:

, Question options:
ient will not have increased adverse drug reactions to the tamoxifen
tial drug-drug interactions that may occur with tamoxifen
elihood of therapeutic failure with tamoxifen treatment
metabolizers of tamoxifen


Several classes of drugs have interactions with cholinergic
blockers. Which of the following is true about these
interactions?
Question options:
narrow therapeutic range given orally may not stay in the GI tract long enough to produce an action.
muscarinic effects may occur with antihistamines.
lockers may decrease the sedative effects of hypnotics.
lockers are contraindicated with antipsychotics.


Absolute contraindications that clinicians must consider when
initiating estrogen therapy include:
Question options:
dysfunctional uterine bleeding
arterial thromboemboli within the prior year
s
.
ove


First-line therapy for treating topical fungal infections such as
tinea corporis (ringworm) or tinea pedis (athlete’s foot) would
be:
Question options:
azole (clotrimazole, miconazole)
ine
lvin microsize
m or ointment

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