Pharmaceutical Calculations (GREEN) 300 QUESTIONS WITH COMPLETE ANSWERS
How many milliliter of U-100 insulin should be used to obtain 50 units of insulin?
a. 5 mL b. 50 mL c. 0.5 mL d. 500 mL Correct Answer: C
How many drops would be prescribed in each dose of a liquid medicine if 20 mL contained 60
doses? The
dispensing dropper calibrates 35 gtts per mL.
a. 12 gtts b. 15 gtts c. 8 gtts d. 23 gtts Correct Answer: A
How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain
1/10 grain?
a. 58 mg b. 480 mg c. 4800 mg d. 4.8mg Correct Answer: B
If a pint of a certain liquid weighs 9200 grains, what is the specific gravity of the liquid?
a. 1.0 b. 1.32 c. 1.276 d. 1.26 Correct Answer: D
How many grams of dextrose are required to prepare 4500 L of a 5% solution?
a. 80,000 g b. 225,000g c. 4 f3 d. 8 f3 Correct Answer: B
How many grams of a drug substance should be dissolved in 250 mL of water to make a 5%
(w/w) solution?
a. 9.6 g b. 13.16 g c. 60 g d. 10 g Correct Answer: B
Convert 5% to mg/mL:
a. 50 mg/mL b. 500 mg/mL c. 5000 mg/mL d. 5 mg/mL Correct Answer: A
In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70%
alcohol?
a. 3 parts / 5 parts
b. 1 part / 1 part
c. 5 parts / 4 parts
d. 4 parts / 5 parts Correct Answer: B
How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to
prepare 1500 mL of a
liquid having a specific gravity of 0.925?
a. 1000 mL (sp gr 0.950) c. 500 mL (sp gr 0.950)
500 mL (sp gr 0.875) 1000 mL (sp gr 0.875)
b. 2250 mL (sp gr 0.950) d. 1125 mL (sp gr 0.950)
1125 mL (sp gr 0.875) 2250 mL (spgr 0.875) Correct Answer: A
Zinc chloride is a three-ion electrolyte, dissociating 80% in a certain concentration. Calculate its
dissociation factor
(I):
a. 2.6 b. 1.6 c. 2.9 d. 3 Correct Answer: A
,If 10 mg of a drug are added to a 500 mL large-volume parenteral fluid, what should be the rate
of flow, in mL/hour,
to deliver 1 mg of drug per hour?
a. 50 mL/hour b. 20 mL/hour c. 500 mL/hour d. 5 mL/hour Correct Answer: A
How many milliequivalents are there in 15 mL of a 50% MgSO4 solution? (mol. Wt. 246)
a. 6.097 mEq b. 60.97 mEq c. 6.96 mEq d. 69.7 mEq Correct Answer: B
You are directed to weigh 10 grams of a substance so as to limit the error to 0.2%. Calculate the
maximum potential
error, in terms of grams, that you would not be permitted to exceed.
a. 0.05 g b. 0.02 g c. 0.002 g d. 0.2 g Correct Answer: B
A prescription is to be taken as follows: 1 tablet q.i.d. the first day; 1 tablet t.i.d. the second day;
1 tablet b.i.d. x 5 d;
and 1 tablet q.d. thereafter. How many tablets should be dispensed to equal a 3-day supply?
a. 18 tablets b. 40 tablets c. 22 tablets d. 47 tablets Correct Answer: B
Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given
oral tetracycline in
doses of 0.011 g/lb body weight every 6 hours. Express the dose in terms of milligrams per
kilogram of body
weight.
a. 5 mg/Kg b. 24.2 mg/Kg c. 25 mg/Kg d. 11 mg/Kg Correct Answer: B
How many colchicines tablets, each containing 600 mcg, may be prepared from 30 g of
colchicines?
a. 50,000 tablets
b. 20,000 tablets
c. 20 tablets
d. 50 tablets Correct Answer: A
Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. How many
milliliters would provide
dose of 40 mcg?
a. 0.04 mL b. 40 Ml c. 40 mL d. 0.4 mL Correct Answer: D
Nitrostat Sublingual tablets are available as 1/200-gr tablets. What is the approximate equivalent
in
milligrams?
a. 0.325 b. 0.077 c. 0.005 d. 0.65 Correct Answer: A
Four thousand (4000) nanograms equals 4:
a. centigrams b. grams c. milligrams d. micrograms Correct Answer: D
,If a physician prescribed 4 grams of aspirin to be taken by a patient daily, about how many 5-
grain tablets should the
patient take each day?
a. 10 tablets b. 12 tablets c. 15 tablets d. 8 tablets Correct Answer: B
he prophylactic dose of riboflavin is 2 mg. How many micrograms of riboflavin are in a multiple
vitamin
capsule containing 1/5 the prophylactic dose?
a. 500 mcg b. 300 mcg c. 5000 mcg d. 200 mcg Correct Answer: B
A commercial package contains thirty-six 200-mg tablets of ibuprofen. How many kilograms of
ibuprofen
were used in the manufacture of 1000 packages of product?
a. 7.2 Kg b. 5 Kg c. 7.8 Kg d. 6.9 Kg Correct Answer: A
How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50 mcg
of the medicinal
substance?
a. 1.25 g b. 12.5 g c. 0.125 g d. 125 g Correct Answer: B
Pico denotes _____ of the basic unit:
a. 10-12
b. 10-15
c. 10-18
d. 10-10 Correct Answer: A
1 milliliter is 1,000x greater than:
a. microliter b. picoliter c. nanoliter d. liter Correct Answer: A
Sudafed cough syrup contains 0.09 g of dextromethorphan hydrobromide in each fluidounce.
How many milligrams
of this agent would be present in each teaspoonful dose?
a. 10 mg b. 12 mg c. 15 mg d. 20 mg Correct Answer: C
The usual dose of digoxin for rapid digitalization is a total of 1.0 mg, divide into two or more
portions at
intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50 mcg/ mL would
provide this dose?
a. 15 mL b. 10 mL c. 25 mL d. 20 mL Correct Answer: D
The dose of beclamethasone, an aerosolized inhalant, is 200 cg twice daily. The commercial
inhaler delvers 50
mcg per metered inhalation and contains 200 inhalations. How many inhalers should be
dispensed to a patient if a
60-day supply is prescribed?
a. 3 b. 2 c. 4 d. 5 Correct Answer: A
, If a physician prescribed Keflex, 250 mg q.i.d. x 10 days, how many milliliters of Keflex
suspension containing 250
mg per 5 mL should be dispensed?
a. 250 mL b. 200 mL c. 150 mL d. 100 mL Correct Answer: B
Terpin hydrate and codeine elixir contains 60 mg of codeine per 30 mL. How much additional
codeine should be
added to 180 mL of the elixir so that each teaspoonful will contain 15 mg of codeine?
a. 180 mg b. 200 mg c. 170 mg d. 190 mg Correct Answer: A
The directions intended for the patient on a prescription read 1 Tbsp a.c. and h.s. for 10 days.
What is the minimum
volume the pharmacist should dispense?
a. 200 mL b. 150 mL c. 600 mL d. 450 mL Correct Answer: C
If the cost of human growth hormone is P40/mg q 4 h six times daily. How many will a 180-lb
patient receive daily?
a. 12 mg b. 164 mg c. 650 mg d. 980 mg Correct Answer: A
The pediatric dose of cefadroxil is 30mg/Kg/day. If a child was given a daily dose of 2
teaspoonfuls of pediatric
suspension containing 125 mg of cefadroxil per 5 mL, what was the weight, in pounds, of the
child?
a. 19 lbs b. 17.3 lbs c. 18.3 lbs d. 18.5 lb Correct Answer: C
A Ferrous Sulfate syrup contains 220 mg of FeSO4.7H2O per teaspoon dose. How many
milligrams of elemental
iron are present in the dose? (mol wt FeSO4.7H2O = 278; at. Wt. of Fe = 55.9, s = 32.1, O = 16,
H = 1.0)
a. 44 mg b. 50 mg c. 88 mg d. 100 mg Correct Answer: A
An antacid tablet contains 80 mg off dried aluminum hydroxide gel and 20 g of magnesium
trisilicate. How many
kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product,
each containing 100
tablets?
a. 2000 Kg b. 20,000 Kg c. 200 Kg d. 8000 Kg Correct Answer: A
An estradiol transdermal system contains in each skin patch 4 mg of estradiol and 0.3mL of
alcohol. How many
liters of alcohol would be required to manufacture a half-million patches?
a. 15 L b. 150 l c. 1,500 L d. 300 L Correct Answer: B
From the ff. formula:
Benzyl benzoate 250 mL
How many milliliter of U-100 insulin should be used to obtain 50 units of insulin?
a. 5 mL b. 50 mL c. 0.5 mL d. 500 mL Correct Answer: C
How many drops would be prescribed in each dose of a liquid medicine if 20 mL contained 60
doses? The
dispensing dropper calibrates 35 gtts per mL.
a. 12 gtts b. 15 gtts c. 8 gtts d. 23 gtts Correct Answer: A
How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain
1/10 grain?
a. 58 mg b. 480 mg c. 4800 mg d. 4.8mg Correct Answer: B
If a pint of a certain liquid weighs 9200 grains, what is the specific gravity of the liquid?
a. 1.0 b. 1.32 c. 1.276 d. 1.26 Correct Answer: D
How many grams of dextrose are required to prepare 4500 L of a 5% solution?
a. 80,000 g b. 225,000g c. 4 f3 d. 8 f3 Correct Answer: B
How many grams of a drug substance should be dissolved in 250 mL of water to make a 5%
(w/w) solution?
a. 9.6 g b. 13.16 g c. 60 g d. 10 g Correct Answer: B
Convert 5% to mg/mL:
a. 50 mg/mL b. 500 mg/mL c. 5000 mg/mL d. 5 mg/mL Correct Answer: A
In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70%
alcohol?
a. 3 parts / 5 parts
b. 1 part / 1 part
c. 5 parts / 4 parts
d. 4 parts / 5 parts Correct Answer: B
How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to
prepare 1500 mL of a
liquid having a specific gravity of 0.925?
a. 1000 mL (sp gr 0.950) c. 500 mL (sp gr 0.950)
500 mL (sp gr 0.875) 1000 mL (sp gr 0.875)
b. 2250 mL (sp gr 0.950) d. 1125 mL (sp gr 0.950)
1125 mL (sp gr 0.875) 2250 mL (spgr 0.875) Correct Answer: A
Zinc chloride is a three-ion electrolyte, dissociating 80% in a certain concentration. Calculate its
dissociation factor
(I):
a. 2.6 b. 1.6 c. 2.9 d. 3 Correct Answer: A
,If 10 mg of a drug are added to a 500 mL large-volume parenteral fluid, what should be the rate
of flow, in mL/hour,
to deliver 1 mg of drug per hour?
a. 50 mL/hour b. 20 mL/hour c. 500 mL/hour d. 5 mL/hour Correct Answer: A
How many milliequivalents are there in 15 mL of a 50% MgSO4 solution? (mol. Wt. 246)
a. 6.097 mEq b. 60.97 mEq c. 6.96 mEq d. 69.7 mEq Correct Answer: B
You are directed to weigh 10 grams of a substance so as to limit the error to 0.2%. Calculate the
maximum potential
error, in terms of grams, that you would not be permitted to exceed.
a. 0.05 g b. 0.02 g c. 0.002 g d. 0.2 g Correct Answer: B
A prescription is to be taken as follows: 1 tablet q.i.d. the first day; 1 tablet t.i.d. the second day;
1 tablet b.i.d. x 5 d;
and 1 tablet q.d. thereafter. How many tablets should be dispensed to equal a 3-day supply?
a. 18 tablets b. 40 tablets c. 22 tablets d. 47 tablets Correct Answer: B
Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given
oral tetracycline in
doses of 0.011 g/lb body weight every 6 hours. Express the dose in terms of milligrams per
kilogram of body
weight.
a. 5 mg/Kg b. 24.2 mg/Kg c. 25 mg/Kg d. 11 mg/Kg Correct Answer: B
How many colchicines tablets, each containing 600 mcg, may be prepared from 30 g of
colchicines?
a. 50,000 tablets
b. 20,000 tablets
c. 20 tablets
d. 50 tablets Correct Answer: A
Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. How many
milliliters would provide
dose of 40 mcg?
a. 0.04 mL b. 40 Ml c. 40 mL d. 0.4 mL Correct Answer: D
Nitrostat Sublingual tablets are available as 1/200-gr tablets. What is the approximate equivalent
in
milligrams?
a. 0.325 b. 0.077 c. 0.005 d. 0.65 Correct Answer: A
Four thousand (4000) nanograms equals 4:
a. centigrams b. grams c. milligrams d. micrograms Correct Answer: D
,If a physician prescribed 4 grams of aspirin to be taken by a patient daily, about how many 5-
grain tablets should the
patient take each day?
a. 10 tablets b. 12 tablets c. 15 tablets d. 8 tablets Correct Answer: B
he prophylactic dose of riboflavin is 2 mg. How many micrograms of riboflavin are in a multiple
vitamin
capsule containing 1/5 the prophylactic dose?
a. 500 mcg b. 300 mcg c. 5000 mcg d. 200 mcg Correct Answer: B
A commercial package contains thirty-six 200-mg tablets of ibuprofen. How many kilograms of
ibuprofen
were used in the manufacture of 1000 packages of product?
a. 7.2 Kg b. 5 Kg c. 7.8 Kg d. 6.9 Kg Correct Answer: A
How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50 mcg
of the medicinal
substance?
a. 1.25 g b. 12.5 g c. 0.125 g d. 125 g Correct Answer: B
Pico denotes _____ of the basic unit:
a. 10-12
b. 10-15
c. 10-18
d. 10-10 Correct Answer: A
1 milliliter is 1,000x greater than:
a. microliter b. picoliter c. nanoliter d. liter Correct Answer: A
Sudafed cough syrup contains 0.09 g of dextromethorphan hydrobromide in each fluidounce.
How many milligrams
of this agent would be present in each teaspoonful dose?
a. 10 mg b. 12 mg c. 15 mg d. 20 mg Correct Answer: C
The usual dose of digoxin for rapid digitalization is a total of 1.0 mg, divide into two or more
portions at
intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50 mcg/ mL would
provide this dose?
a. 15 mL b. 10 mL c. 25 mL d. 20 mL Correct Answer: D
The dose of beclamethasone, an aerosolized inhalant, is 200 cg twice daily. The commercial
inhaler delvers 50
mcg per metered inhalation and contains 200 inhalations. How many inhalers should be
dispensed to a patient if a
60-day supply is prescribed?
a. 3 b. 2 c. 4 d. 5 Correct Answer: A
, If a physician prescribed Keflex, 250 mg q.i.d. x 10 days, how many milliliters of Keflex
suspension containing 250
mg per 5 mL should be dispensed?
a. 250 mL b. 200 mL c. 150 mL d. 100 mL Correct Answer: B
Terpin hydrate and codeine elixir contains 60 mg of codeine per 30 mL. How much additional
codeine should be
added to 180 mL of the elixir so that each teaspoonful will contain 15 mg of codeine?
a. 180 mg b. 200 mg c. 170 mg d. 190 mg Correct Answer: A
The directions intended for the patient on a prescription read 1 Tbsp a.c. and h.s. for 10 days.
What is the minimum
volume the pharmacist should dispense?
a. 200 mL b. 150 mL c. 600 mL d. 450 mL Correct Answer: C
If the cost of human growth hormone is P40/mg q 4 h six times daily. How many will a 180-lb
patient receive daily?
a. 12 mg b. 164 mg c. 650 mg d. 980 mg Correct Answer: A
The pediatric dose of cefadroxil is 30mg/Kg/day. If a child was given a daily dose of 2
teaspoonfuls of pediatric
suspension containing 125 mg of cefadroxil per 5 mL, what was the weight, in pounds, of the
child?
a. 19 lbs b. 17.3 lbs c. 18.3 lbs d. 18.5 lb Correct Answer: C
A Ferrous Sulfate syrup contains 220 mg of FeSO4.7H2O per teaspoon dose. How many
milligrams of elemental
iron are present in the dose? (mol wt FeSO4.7H2O = 278; at. Wt. of Fe = 55.9, s = 32.1, O = 16,
H = 1.0)
a. 44 mg b. 50 mg c. 88 mg d. 100 mg Correct Answer: A
An antacid tablet contains 80 mg off dried aluminum hydroxide gel and 20 g of magnesium
trisilicate. How many
kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product,
each containing 100
tablets?
a. 2000 Kg b. 20,000 Kg c. 200 Kg d. 8000 Kg Correct Answer: A
An estradiol transdermal system contains in each skin patch 4 mg of estradiol and 0.3mL of
alcohol. How many
liters of alcohol would be required to manufacture a half-million patches?
a. 15 L b. 150 l c. 1,500 L d. 300 L Correct Answer: B
From the ff. formula:
Benzyl benzoate 250 mL
