ABO system discovered in _____ by _____ Correct Answer: 1900, Karl Landsteiner
Human red blood cells can be classified as Correct Answer: A, B, O or AB
Almost all healthy people older than 4-6 months of age have naturally occurring ______ to the
ABO ______ they lack Correct Answer: antibodies, antigens
If the ABO antigen is present on the cells the corresponding ______ will be absent in the serum
Correct Answer: antibody
If the ABO antibody is present in the serum the corresponding ______ will be absent on the cells
Correct Answer: antigen
ABO Blood Group System Correct Answer: most significant for transfusion and transplantation
practice due to mutual antibodies being predictably present in the sera whose RBCs lack the
antigen
Monoclonal Antibodies Correct Answer: derived from culture cell lines, which have several
advantages over conventional human and plant ABO reagents
Major Advantage of Monoclonal Antibodies Correct Answer: Reproducibility
anti-A reagent is Correct Answer: BLUE
anti-B reagent is Correct Answer: YELLOW
anti-A1 and anti-H are Correct Answer: colorless & used to resolve ABO discrepancies
Inverse Reciprocal Relationship Correct Answer: between forward and reverse type, one serving
as a check on the other
Forward Grouping Correct Answer: testing for an individual's ABO antigens (unknown
antigens) using antisera (known ABO antibodies)
Reverse Grouping Correct Answer: testing for the presence or absence of individual ABO
antibodies (unknown antibodies) using reagent RBCs (known antigens)
Percentage of Caucasians/AAs with group O Correct Answer: 45%, 49%
Percentage of Caucasians/AAs with group A Correct Answer: 40%, 27%
Percentage of Caucasians/AAs with group B Correct Answer: 11%, 19%
Percentage of Caucasians/AAs with group AB Correct Answer: 4% (both)