Pharmaceutical Calculations (300 questions) With Complete Solutions
How many milliliter of U-100 insulin should be used to obtain 50units of insulin?
a. 5ml
b. 50mL
c. 0.5mL
d.500mL Correct Answer: c. 0.5mL
How many drops would be prescribed in each dose of a liquid medicine if 20mL contained 60
doses? The dropper calibrates 35gtts per mL.
a. 12gtts
b.15gtts
c. 8gtts
d. 23gtts Correct Answer: a. 12gtts
How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain
1/10 grain?
a. 58mg
b. 480mg
c. 4800mg
d. 4.8mg Correct Answer: b. 480mg
If a pint of a certain liquid weights 9200 grains, what is the specific gravity of the liquid?
a. 1.0
b. 1.32
c. 1.276
d. 1.26 Correct Answer: d. 1.26
How many grams of dextrose are required to prepare 4500 L of a 5% solution?
a. 80,000 g
b. 225,000 g
c. 4 f3
d. 8 f3 Correct Answer: b. 225,000 g
How many grams of drug substance should be dissolved in 250 mL of water to make a 5%(w/w)
solution?
a. 9.6g
b.13.16g
c.60 g
d. 10g Correct Answer: b.13.16g
Convert 5% to mg/mL
a. 50mg/mL
b.500mg/mL
c.5000mg/mL
d. 5mg/mL Correct Answer: a. 50mg/mL
,In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70%
alcohol?
a. 3parts/5parts
b.1part/1part
c.5parts/4parts
d.4parts/5parts Correct Answer: b.1part/1part
How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to
prepare 1500mL of a liquid having a specific gravity of 0.925?
a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875)
b.2250mL (sp.gr 0.950) 1125mL (sp gr 0.875)
c.500mL (sp.gr 0.950) 1000mL(sp gr 0.875)
d. 1125mL (sp.gr 0.950) 2250mL(sp gr 0.875) Correct Answer: a.1000mL (sp.gr 0.950) 500mL
(sp gr 0.875)
Zinc chloride is a three-ion electrolyte,dissociating 80% in a certain concentration. Calculate its
dissociation factor(I)
a. 2.6
b. 1.6
c. 2.9
d. 3 Correct Answer: a. 2.6
If 10mg of a drug are added to a 500mL large-volume parenteral fluid, what should be the rate of
flow, in mL/hr, to deliver 1mg of drug per hour?
a. 50mL/hr
b. 20mL/hr
c.500mL/hr
d.5mL/hr Correct Answer: a. 50mL/hr
You are directed to weigh 10g of substance so as to limit the error to 0.2%. calculate the
maximum potential error, in terms of grams, that you would not be permitted to exceed.
a. 0.05g
b. 0.02g
c. 0.002g
d. 0.2g Correct Answer: b. 0.02g
How many milliequivalents are there in 15mL of a 50% MgSO4 solution? (mol wt= 246)
a. 6.097 mEq
b. 60.97 mEq
c. 6.96 mEq
d.69.7 mEq Correct Answer: b. 60.97 mEq
A prescription is to taken as follows: 1 tab q.i.d. the first day; 1 tab t.i.d. the second day; 1 tab
b.i.d. x 5 d; and 1 tab q.d. thereafter. How many tablets should be dispensed to equal a 3-day
supply?
,a. 18 tab
b. 40 tab
c. 22 tab
d. 47 tab Correct Answer: b. 40 tab
Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given
oral tetracycline in doses of 0.011g/lb body weight every 6 hrs. express the doses of milligrams
per kilogram of body weight.
a. 5mg/kg
b.24.2mg/kg
c.25mg/kg
d. 11mg/kg Correct Answer: b.24.2mg/kg
How many cochicines tablets, each containing 00mcg, may be prepared from 30g of colchicines?
a. 50,000 tab
b.20,000 tab
c.20 tab
d.50 tab Correct Answer: a. 50,000 tab
Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. how many
milliliters would provide dose of 40 mcg?
a. 0.04mL
b. 40mL
c. 40mL
d. 0.4mL Correct Answer: d. 0.4mL
Nitrostat sublingual tablets are available as 1/200gr tablets. What is the approximate equivalent
in milligrams?
a. 0.325
b. 0.077
c. 0.005
d. 0.65 Correct Answer: a. 0.325
Four thousand nanograms equals 4:
a. centigrams
b. grams
c. milligrams
d. micrograms Correct Answer: d. micrograms
The prophylactic dose of riboflavin is 2mg. how many mcg of riboflavin are in a multiple
vitamin capsule containing 1/5 the prophylactic dose?
a.500mcg
b.400mcg
c.5000mcg
d.200mcg Correct Answer: b.400mcg
, If a physician prescribed 4g of aspirin to be taken by a patient daily, about how many 5-grain
tablets should the patient take each day?
a. 10 tab
b. 12 tab
c.15 tab
d.8 tab Correct Answer: b. 12 tab
A commercial package contains thirty-six 200mg tablets of ibuprofen. How many kilograms of
ibuprofen were used in the manufacture of 1000 package of the product?
a. 7.2 kg
b. 5kg
c. 7.8kg
d. 6.9 kg Correct Answer: a. 7.2 kg
How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50mcg
of the medicinal substance?
a. 1.25g
b.12.5g
c. 0.125g
d.125g Correct Answer: c. 0.125g
Pico denotes _______ of the basic unit
a. 10^-12
b. 10^-15
c.10^-18
d. 10^-10 Correct Answer: a. 10^-12
1 milliliter is 1000x greater than:
a. microliter
b.picoliter
c.nanoliter
d.liter Correct Answer: a. microliter
Sudafed cough syrup contains 0.0g of dextromethorphan hydrobromide in each fluidounce. How
many milligrams of this agent would be present in each teaspoonful dose?
a. 10mg
b. 12mg
c. 15mg
d. 20mg Correct Answer: c. 15mg
The usual dose of digoxin for rapid digitalization is a total of 1.0mg, divide into two or more
portion at intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50mcg/mL
would provide this dose?
a. 15mL
b. 10mL
c.25mL
How many milliliter of U-100 insulin should be used to obtain 50units of insulin?
a. 5ml
b. 50mL
c. 0.5mL
d.500mL Correct Answer: c. 0.5mL
How many drops would be prescribed in each dose of a liquid medicine if 20mL contained 60
doses? The dropper calibrates 35gtts per mL.
a. 12gtts
b.15gtts
c. 8gtts
d. 23gtts Correct Answer: a. 12gtts
How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain
1/10 grain?
a. 58mg
b. 480mg
c. 4800mg
d. 4.8mg Correct Answer: b. 480mg
If a pint of a certain liquid weights 9200 grains, what is the specific gravity of the liquid?
a. 1.0
b. 1.32
c. 1.276
d. 1.26 Correct Answer: d. 1.26
How many grams of dextrose are required to prepare 4500 L of a 5% solution?
a. 80,000 g
b. 225,000 g
c. 4 f3
d. 8 f3 Correct Answer: b. 225,000 g
How many grams of drug substance should be dissolved in 250 mL of water to make a 5%(w/w)
solution?
a. 9.6g
b.13.16g
c.60 g
d. 10g Correct Answer: b.13.16g
Convert 5% to mg/mL
a. 50mg/mL
b.500mg/mL
c.5000mg/mL
d. 5mg/mL Correct Answer: a. 50mg/mL
,In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70%
alcohol?
a. 3parts/5parts
b.1part/1part
c.5parts/4parts
d.4parts/5parts Correct Answer: b.1part/1part
How many milliliters of two liquids with specific gravities of 0.950 and 0.875 should be used to
prepare 1500mL of a liquid having a specific gravity of 0.925?
a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875)
b.2250mL (sp.gr 0.950) 1125mL (sp gr 0.875)
c.500mL (sp.gr 0.950) 1000mL(sp gr 0.875)
d. 1125mL (sp.gr 0.950) 2250mL(sp gr 0.875) Correct Answer: a.1000mL (sp.gr 0.950) 500mL
(sp gr 0.875)
Zinc chloride is a three-ion electrolyte,dissociating 80% in a certain concentration. Calculate its
dissociation factor(I)
a. 2.6
b. 1.6
c. 2.9
d. 3 Correct Answer: a. 2.6
If 10mg of a drug are added to a 500mL large-volume parenteral fluid, what should be the rate of
flow, in mL/hr, to deliver 1mg of drug per hour?
a. 50mL/hr
b. 20mL/hr
c.500mL/hr
d.5mL/hr Correct Answer: a. 50mL/hr
You are directed to weigh 10g of substance so as to limit the error to 0.2%. calculate the
maximum potential error, in terms of grams, that you would not be permitted to exceed.
a. 0.05g
b. 0.02g
c. 0.002g
d. 0.2g Correct Answer: b. 0.02g
How many milliequivalents are there in 15mL of a 50% MgSO4 solution? (mol wt= 246)
a. 6.097 mEq
b. 60.97 mEq
c. 6.96 mEq
d.69.7 mEq Correct Answer: b. 60.97 mEq
A prescription is to taken as follows: 1 tab q.i.d. the first day; 1 tab t.i.d. the second day; 1 tab
b.i.d. x 5 d; and 1 tab q.d. thereafter. How many tablets should be dispensed to equal a 3-day
supply?
,a. 18 tab
b. 40 tab
c. 22 tab
d. 47 tab Correct Answer: b. 40 tab
Tetracycline has been shown to form a calcium complex in bone-forming tissue in infants given
oral tetracycline in doses of 0.011g/lb body weight every 6 hrs. express the doses of milligrams
per kilogram of body weight.
a. 5mg/kg
b.24.2mg/kg
c.25mg/kg
d. 11mg/kg Correct Answer: b.24.2mg/kg
How many cochicines tablets, each containing 00mcg, may be prepared from 30g of colchicines?
a. 50,000 tab
b.20,000 tab
c.20 tab
d.50 tab Correct Answer: a. 50,000 tab
Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. how many
milliliters would provide dose of 40 mcg?
a. 0.04mL
b. 40mL
c. 40mL
d. 0.4mL Correct Answer: d. 0.4mL
Nitrostat sublingual tablets are available as 1/200gr tablets. What is the approximate equivalent
in milligrams?
a. 0.325
b. 0.077
c. 0.005
d. 0.65 Correct Answer: a. 0.325
Four thousand nanograms equals 4:
a. centigrams
b. grams
c. milligrams
d. micrograms Correct Answer: d. micrograms
The prophylactic dose of riboflavin is 2mg. how many mcg of riboflavin are in a multiple
vitamin capsule containing 1/5 the prophylactic dose?
a.500mcg
b.400mcg
c.5000mcg
d.200mcg Correct Answer: b.400mcg
, If a physician prescribed 4g of aspirin to be taken by a patient daily, about how many 5-grain
tablets should the patient take each day?
a. 10 tab
b. 12 tab
c.15 tab
d.8 tab Correct Answer: b. 12 tab
A commercial package contains thirty-six 200mg tablets of ibuprofen. How many kilograms of
ibuprofen were used in the manufacture of 1000 package of the product?
a. 7.2 kg
b. 5kg
c. 7.8kg
d. 6.9 kg Correct Answer: a. 7.2 kg
How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50mcg
of the medicinal substance?
a. 1.25g
b.12.5g
c. 0.125g
d.125g Correct Answer: c. 0.125g
Pico denotes _______ of the basic unit
a. 10^-12
b. 10^-15
c.10^-18
d. 10^-10 Correct Answer: a. 10^-12
1 milliliter is 1000x greater than:
a. microliter
b.picoliter
c.nanoliter
d.liter Correct Answer: a. microliter
Sudafed cough syrup contains 0.0g of dextromethorphan hydrobromide in each fluidounce. How
many milligrams of this agent would be present in each teaspoonful dose?
a. 10mg
b. 12mg
c. 15mg
d. 20mg Correct Answer: c. 15mg
The usual dose of digoxin for rapid digitalization is a total of 1.0mg, divide into two or more
portion at intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50mcg/mL
would provide this dose?
a. 15mL
b. 10mL
c.25mL
