TEST BANK; Full Set Of NR546 / NR
546 ACTUAL MIDTERM EXAM,NR 546
/ NR546 Week 3 Actual Quiz 2022 And
NR 546 / NR546 Actual Final Exam
2022 Prediction| Verified
Table of Contents
NR546 / NR 546 ACTUAL MIDTERM EXAM ................................................................................................... 2
NR 546 / NR546 Week 3 Actual Quiz 2022 questions (All correct answers, Already graded A)................. 23
NR 546 / NR546 Actual Final Exam 2022 Prediction questions (All correct answers, Already graded A) .. 38
,NR546 / NR 546 ACTUAL MIDTERM EXAM
Treatment with dopamine 2 receptor antagonists/partial agonists with
antipsychotic pr the:
A. Mesolimbic/mesostriatal pathway
B. Mesocortical pathway
C. Mesolimbic/mesostriatal and mesocortical pathways
-A 44-year-old male with schizophrenia has been taking an antipsychotic medication since initial
diagnosis twelve years ago. He has recently begun experiencing difficulty with fluid movement of his
arms as well as involuntary facial grimaces. Which of the following likely underlies these symptoms?
A. Upregulation of serotonin 2A receptors
B. Downregulation of serotonin 2A receptors
C. Upregulation of dopamine 2 receptors
D. Downregulation of dopamine 2 receptors
C. Upregulation of dopamine 2 receptors {{Correct Ans- C. Upregulation of dopamine 2 receptors
Sam is a 76-year-old patient with Parkinson's disease psychosis who
demonstrated a rtreatment with a dopamine 2/serotonin 1A partial agonist.
Where on the dopamine agon
A. Nearly full dopamine agonist
B. Nearly full dopamine antagonist
C. Intermediate between full dopamine agonist and full dopamine antagonist
-Patrick is a 22-year-old male who recently experienced a psychotic-like episode after trying MDMA
("ecstasy") while at a party. A key binding site for hallucinogens is the:
A. GABA-A receptor
B. Cannabinoid 1 receptor
C. Serotonin 2A receptor
D. Serotonin 2C receptor {{Correct Ans- C. Serotonin 2A receptor
,-38-year-old woman was diagnosed with schizophrenia approximately two years ago and after multiple
trials of different medications has been maintained on haloperidol for the last several months with good
response. Two weeks ago she began exhibiting mild motor symptoms representative of parkinsonism.
Which of the following would be the most appropriate adjunct medication for this patient?
A. Alpha 1 adrenergic agonist
B. Cholinesterase inhibitor
C. Histamine 1 antagonist
D. Muscarinic 1 antagonist {{Correct Ans- D. Muscarinic 1 antagonist
-A 21-year-old man with first-episode psychosis is prescribed an antipsychotic that has serotonin 2A
antagonism. According to a leading hypothesis, blockade of serotonin 2A receptors in the cortex can
ultimately increase dopamine in the striatum through what initial mechanism?
A. Decreased glutamate and thus increased GABA in the brainstem
B. Decreased glutamate and thus decreased GABA in the brainstem
C. Increased glutamate and thus decreased GABA in the brainstem
D. Increased glutamate and thus increased GABA in the brainstem {{Correct Ans- B. Decreased
glutamate and thus decreased GABA in the brainstem
-he majority of atypical antipsychotics:
A. Have higher affinity for dopamine 2 receptors than for serotonin 2A receptors
C. Have comparable affinity for dopamine 2 and serotonin 2A receptors {{Correct Ans- B. Have higher
affinity for serotonin 2A receptors than for dopamine 2 receptors
-Dopamine 2 partial agonists cause receptor output that is less than that caused by dopamine but more
than that caused by a conventional antipsychotic.
A. True
B. False {{Correct Ans- A. True
, -A 44 yr-old woman with schizophrenia and a history of depression has developed tardive dyskinesia
after taking haloperidol 15 mg/day for 2 yrs. Which of the following would be the most appropriate
pharmacologic option to manage her tardive dyskinesia?
A. Amantadine
B. Benztropine
C. Clonazepam
D. Reserpine {{Correct Ans- C. Clonazepam
-Which of the following is considered the pleasure center of the brain?
A. Cortico-striatal-thalamic-cortical loop
B. Mesolimbic dopamine pathway
C. Mesocortical dopamine pathway
D. None of the above {{Correct Ans- B. Mesolimbic dopamine pathway
-The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-
seeking behavior.
A. True
B. False {{Correct Ans- A. True
-What role does the amygdala play in substance abuse?
A. Releases phasic bursts of dopamine to the nucleus accumbens when drugs of abuse are present
B. Communicates to the ventral tegmental area when cues related to drugs of abuse are present
C. Site of binding for most drugs of abuse
D. A and B
E. A, B, and C {{Correct Ans- B. Communicates to the ventral tegmental area when cues related to drugs
of abuse are present
546 ACTUAL MIDTERM EXAM,NR 546
/ NR546 Week 3 Actual Quiz 2022 And
NR 546 / NR546 Actual Final Exam
2022 Prediction| Verified
Table of Contents
NR546 / NR 546 ACTUAL MIDTERM EXAM ................................................................................................... 2
NR 546 / NR546 Week 3 Actual Quiz 2022 questions (All correct answers, Already graded A)................. 23
NR 546 / NR546 Actual Final Exam 2022 Prediction questions (All correct answers, Already graded A) .. 38
,NR546 / NR 546 ACTUAL MIDTERM EXAM
Treatment with dopamine 2 receptor antagonists/partial agonists with
antipsychotic pr the:
A. Mesolimbic/mesostriatal pathway
B. Mesocortical pathway
C. Mesolimbic/mesostriatal and mesocortical pathways
-A 44-year-old male with schizophrenia has been taking an antipsychotic medication since initial
diagnosis twelve years ago. He has recently begun experiencing difficulty with fluid movement of his
arms as well as involuntary facial grimaces. Which of the following likely underlies these symptoms?
A. Upregulation of serotonin 2A receptors
B. Downregulation of serotonin 2A receptors
C. Upregulation of dopamine 2 receptors
D. Downregulation of dopamine 2 receptors
C. Upregulation of dopamine 2 receptors {{Correct Ans- C. Upregulation of dopamine 2 receptors
Sam is a 76-year-old patient with Parkinson's disease psychosis who
demonstrated a rtreatment with a dopamine 2/serotonin 1A partial agonist.
Where on the dopamine agon
A. Nearly full dopamine agonist
B. Nearly full dopamine antagonist
C. Intermediate between full dopamine agonist and full dopamine antagonist
-Patrick is a 22-year-old male who recently experienced a psychotic-like episode after trying MDMA
("ecstasy") while at a party. A key binding site for hallucinogens is the:
A. GABA-A receptor
B. Cannabinoid 1 receptor
C. Serotonin 2A receptor
D. Serotonin 2C receptor {{Correct Ans- C. Serotonin 2A receptor
,-38-year-old woman was diagnosed with schizophrenia approximately two years ago and after multiple
trials of different medications has been maintained on haloperidol for the last several months with good
response. Two weeks ago she began exhibiting mild motor symptoms representative of parkinsonism.
Which of the following would be the most appropriate adjunct medication for this patient?
A. Alpha 1 adrenergic agonist
B. Cholinesterase inhibitor
C. Histamine 1 antagonist
D. Muscarinic 1 antagonist {{Correct Ans- D. Muscarinic 1 antagonist
-A 21-year-old man with first-episode psychosis is prescribed an antipsychotic that has serotonin 2A
antagonism. According to a leading hypothesis, blockade of serotonin 2A receptors in the cortex can
ultimately increase dopamine in the striatum through what initial mechanism?
A. Decreased glutamate and thus increased GABA in the brainstem
B. Decreased glutamate and thus decreased GABA in the brainstem
C. Increased glutamate and thus decreased GABA in the brainstem
D. Increased glutamate and thus increased GABA in the brainstem {{Correct Ans- B. Decreased
glutamate and thus decreased GABA in the brainstem
-he majority of atypical antipsychotics:
A. Have higher affinity for dopamine 2 receptors than for serotonin 2A receptors
C. Have comparable affinity for dopamine 2 and serotonin 2A receptors {{Correct Ans- B. Have higher
affinity for serotonin 2A receptors than for dopamine 2 receptors
-Dopamine 2 partial agonists cause receptor output that is less than that caused by dopamine but more
than that caused by a conventional antipsychotic.
A. True
B. False {{Correct Ans- A. True
, -A 44 yr-old woman with schizophrenia and a history of depression has developed tardive dyskinesia
after taking haloperidol 15 mg/day for 2 yrs. Which of the following would be the most appropriate
pharmacologic option to manage her tardive dyskinesia?
A. Amantadine
B. Benztropine
C. Clonazepam
D. Reserpine {{Correct Ans- C. Clonazepam
-Which of the following is considered the pleasure center of the brain?
A. Cortico-striatal-thalamic-cortical loop
B. Mesolimbic dopamine pathway
C. Mesocortical dopamine pathway
D. None of the above {{Correct Ans- B. Mesolimbic dopamine pathway
-The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-
seeking behavior.
A. True
B. False {{Correct Ans- A. True
-What role does the amygdala play in substance abuse?
A. Releases phasic bursts of dopamine to the nucleus accumbens when drugs of abuse are present
B. Communicates to the ventral tegmental area when cues related to drugs of abuse are present
C. Site of binding for most drugs of abuse
D. A and B
E. A, B, and C {{Correct Ans- B. Communicates to the ventral tegmental area when cues related to drugs
of abuse are present
