MEDICINE
Section A
1. Hematology........................................................................................................1041
2. Cardiovascular System......................................................................................1066
3. Gastrointestinal System ....................................................................................1091
4. Respiratory System............................................................................................1102
5. Kidney and Urinary Tract....................................................................................1115
6. Liver and Biliary Tract........................................................................................1131
7. Endocrinology....................................................................................................1143
8. Connective Tissue Disorders..............................................................................1158
9. Nervous System.................................................................................................1169
10. Acid-Base Disorders..........................................................................................1188
11. Genetic Disorders..............................................................................................1191
12. Miscellaneous....................................................................................................1196
Section B
Practice Questions.......................................................................................1209
(Comprising of Questions from Recent Exams and NEET Pattern Questions)
,
, Section A
1. HEMATOLOGY
A. Anemias
B. Anemia of Chronic Diseases
C. Thalassemias
D. Myeloproliferative Disorders
E. Acute Leukemias
F. Chronic Leukemias and Lymphomas
G. Plasma Cell Disorders
H. Bleeding and Coagulation Disorders
I. Blood Transfusion
J. Miscellaneous
, 1042 Jaypee’s Triple A
HEMATOLOGY (QUESTIONS)
8. Autoimmune haemolytic anemia is seen in:
A. ANEMIAS a. CLL
b. CML
1. Earliest change in Iron deficiency anaemia is: (UP 2009)
c. ALL
a. Erythroid hyperplasia
d. AML
b. Subjective feeling of the body and increased appetite
Ref: Harrison’s 18/e p449, 923
c. Lymphoid erythroplasia
d. Reticulocytosis 9. Coombs’ positive hemolytic anemia associated with:
Ref: Harrison’s 18/e p848, 17/e p632 a. TTP (AP 2010)
b. PAN
2. Which of the following is not a characteristic of Fanconi’s
c. SLE
anemia? (Feb DP PGMEE 2009)
d. HUS
a. Hematologic abnormalities in infancy
Ref: Harrison’s 18/e p872-873, 876
b. Pancytopenia
c. Skeletal anomalies 10. A plastic crisis can originate from congenital hemolytic
d. Chromosome fragility anemia, especially when exacerbated by the infection of:
Ref: Harrison’s 18/e p496, 889 a. Cytomegalo virus (AP 2011)
b. Coxsackie virus
3. First increased of reticulocyte count occurs after how many
c. Parvo B19 virus
hours of iron therapy: (Kerela PG 2008)
d. Herpes simplex virus
a. 48-72 hrs
Ref: Harrison’s 18/e p861, 872
b. 24 hrs
c. 96 hrs 11. Pulmonary embolism is seen in all except:
d. 6 hrs a. Fanconi’s anemia (DP PGMEE 2010)
Ref: OPGhai 6/e p302 b. Paroxysmal nocturnal haemoglobinuria
c. Oral contraception
4. In sickle cell anemia: (Kerala PG 10)
d. Old age
a. Peripheral smear shows microcytosis
Ref: Harrison’s 18/e p2090, 17/e p1563
b. There is defective synthesis of alpha chains
c. Autosplenectomy occurs due to vascular thrombosis and 12. The mother has sickle cell disease; Father is normal;
infarction Chances of children having sickle cell disease and sickle
Ref: Harrison’s 18/e p855-856, 17/e p637-38 cell trait respectively are: (AI 2001)
a. 0 and 100%
5. A good index of body iron stores is: (MP PG 2008)
b. 25 and 25%
a. Serum iron level
c. 50 and 50%
b. Serum total iron binding capacity
d. 10 and 50% Ref: Harrison’s 18/e p1855
c. Serum ferritin level
d. Serum haptoglobin level 13. Which of the following are not associated with microcytic
Ref: Harrison’s 18/e p455, 17/e p360 hypochromic RBCs on Peripheral smear? (PGI 2009)
a. Iron Deficiency Anemia
6. Macrocytosis without myeloblastic changes occur with:
b. Lead
a. Pernicious anemia (MP PG 2008)
c. Sideroblastic anemia
b. Aplastic anemia
d. Sickle Cell Anemia
c. Sideroplastic anemia
e. Hereditary spherocytosis
MEDICINE
d. Sickle cell anemia
Ref: Harrison’s 18/e p848, 17/e p632
Ref: Harrison’s 18/e p867, 17/e p649
14. Which of the following is not expected in a case of
7. Drymouth, swelling in the lower esophagus, smooth tongue
Microcytic Hypochromic Anemia: (DNB 2009)
and, craving for ice or clay are features of: (UP 2009)
a. Reduced serum Iron
a. Folic acid deficiency
b. Reduced Total RBC distribution Width
b. Iron deficiency
c. Normal Ferritin levels
c. Biotin deficiency
d. Increased TIBC
d. Riboflavin deficiency
Ref: Harrison’s 18/e p847
Ref: CMDT 09 428
Ans. 1. d. Reticulocytosis 2. a. Hematologic abnormalities... 3. a. 48-72 hrs 4. c. Autosplenectomy occurs...
5. c. Serum ferritin level 6. a. Pernicious anemia 7. b. Iron deficiency 8. a. CLL
9. c. SLE 10. c. Parvo B19 virus 11. a. Fanconi’s anemia 12. a. 0 and 100%
13. d and e 14. b. Reduced Total RBC...
Section A
1. Hematology........................................................................................................1041
2. Cardiovascular System......................................................................................1066
3. Gastrointestinal System ....................................................................................1091
4. Respiratory System............................................................................................1102
5. Kidney and Urinary Tract....................................................................................1115
6. Liver and Biliary Tract........................................................................................1131
7. Endocrinology....................................................................................................1143
8. Connective Tissue Disorders..............................................................................1158
9. Nervous System.................................................................................................1169
10. Acid-Base Disorders..........................................................................................1188
11. Genetic Disorders..............................................................................................1191
12. Miscellaneous....................................................................................................1196
Section B
Practice Questions.......................................................................................1209
(Comprising of Questions from Recent Exams and NEET Pattern Questions)
,
, Section A
1. HEMATOLOGY
A. Anemias
B. Anemia of Chronic Diseases
C. Thalassemias
D. Myeloproliferative Disorders
E. Acute Leukemias
F. Chronic Leukemias and Lymphomas
G. Plasma Cell Disorders
H. Bleeding and Coagulation Disorders
I. Blood Transfusion
J. Miscellaneous
, 1042 Jaypee’s Triple A
HEMATOLOGY (QUESTIONS)
8. Autoimmune haemolytic anemia is seen in:
A. ANEMIAS a. CLL
b. CML
1. Earliest change in Iron deficiency anaemia is: (UP 2009)
c. ALL
a. Erythroid hyperplasia
d. AML
b. Subjective feeling of the body and increased appetite
Ref: Harrison’s 18/e p449, 923
c. Lymphoid erythroplasia
d. Reticulocytosis 9. Coombs’ positive hemolytic anemia associated with:
Ref: Harrison’s 18/e p848, 17/e p632 a. TTP (AP 2010)
b. PAN
2. Which of the following is not a characteristic of Fanconi’s
c. SLE
anemia? (Feb DP PGMEE 2009)
d. HUS
a. Hematologic abnormalities in infancy
Ref: Harrison’s 18/e p872-873, 876
b. Pancytopenia
c. Skeletal anomalies 10. A plastic crisis can originate from congenital hemolytic
d. Chromosome fragility anemia, especially when exacerbated by the infection of:
Ref: Harrison’s 18/e p496, 889 a. Cytomegalo virus (AP 2011)
b. Coxsackie virus
3. First increased of reticulocyte count occurs after how many
c. Parvo B19 virus
hours of iron therapy: (Kerela PG 2008)
d. Herpes simplex virus
a. 48-72 hrs
Ref: Harrison’s 18/e p861, 872
b. 24 hrs
c. 96 hrs 11. Pulmonary embolism is seen in all except:
d. 6 hrs a. Fanconi’s anemia (DP PGMEE 2010)
Ref: OPGhai 6/e p302 b. Paroxysmal nocturnal haemoglobinuria
c. Oral contraception
4. In sickle cell anemia: (Kerala PG 10)
d. Old age
a. Peripheral smear shows microcytosis
Ref: Harrison’s 18/e p2090, 17/e p1563
b. There is defective synthesis of alpha chains
c. Autosplenectomy occurs due to vascular thrombosis and 12. The mother has sickle cell disease; Father is normal;
infarction Chances of children having sickle cell disease and sickle
Ref: Harrison’s 18/e p855-856, 17/e p637-38 cell trait respectively are: (AI 2001)
a. 0 and 100%
5. A good index of body iron stores is: (MP PG 2008)
b. 25 and 25%
a. Serum iron level
c. 50 and 50%
b. Serum total iron binding capacity
d. 10 and 50% Ref: Harrison’s 18/e p1855
c. Serum ferritin level
d. Serum haptoglobin level 13. Which of the following are not associated with microcytic
Ref: Harrison’s 18/e p455, 17/e p360 hypochromic RBCs on Peripheral smear? (PGI 2009)
a. Iron Deficiency Anemia
6. Macrocytosis without myeloblastic changes occur with:
b. Lead
a. Pernicious anemia (MP PG 2008)
c. Sideroblastic anemia
b. Aplastic anemia
d. Sickle Cell Anemia
c. Sideroplastic anemia
e. Hereditary spherocytosis
MEDICINE
d. Sickle cell anemia
Ref: Harrison’s 18/e p848, 17/e p632
Ref: Harrison’s 18/e p867, 17/e p649
14. Which of the following is not expected in a case of
7. Drymouth, swelling in the lower esophagus, smooth tongue
Microcytic Hypochromic Anemia: (DNB 2009)
and, craving for ice or clay are features of: (UP 2009)
a. Reduced serum Iron
a. Folic acid deficiency
b. Reduced Total RBC distribution Width
b. Iron deficiency
c. Normal Ferritin levels
c. Biotin deficiency
d. Increased TIBC
d. Riboflavin deficiency
Ref: Harrison’s 18/e p847
Ref: CMDT 09 428
Ans. 1. d. Reticulocytosis 2. a. Hematologic abnormalities... 3. a. 48-72 hrs 4. c. Autosplenectomy occurs...
5. c. Serum ferritin level 6. a. Pernicious anemia 7. b. Iron deficiency 8. a. CLL
9. c. SLE 10. c. Parvo B19 virus 11. a. Fanconi’s anemia 12. a. 0 and 100%
13. d and e 14. b. Reduced Total RBC...
