Hypersensitivity & autoimmune
MCQ set 2
1. Serum injection may result in the following types of hypersensitivity:
a. Type I
b. Type II
c. Type III
d. A&B
e. A&C
E
2. After injection of anti diphtheritic serum ,patient had severe hypotension,
bronchoconstriction & fainting few minuts after injection – the patient had which type
of hypersensetivity :
a. Type I
b. Type II
c. Type III
d. Type IV
A
3. in serum sickness,patient had hypotension, bronchoconstriction & fainting 24 hours
after serum injection – the patient had which type of hypersensetivity :
a. Type I
b. Type II
c. Type III
d. Type IV
C
4. In skin test for type I hypersensitivity (prick test)
The predicted skin change is:
a. Wheal & flair احمرار وتورم
b. Induration مكان متورم وصلب
c. Ulceration تقرح
d. Non of the above
A
5. In tuberculosis (type IV hypersensitivity) the immune cells involved in the
granuloma formation تكتل من خاليا المناعه حول بكتيريا السل
are the following except:
a. CD4 Th1 cells
b. Macrophages
c. CD8 cytotoxic T cells
d. B lymphocytes
D
1
, Hypersensitivity & autoimmune
MCQ set 2
6. A patient skin tested with PPD to determine previous exposure to M. tuberculosis
develops induration at the skin test. Histologically, the reaction site would most
probably show:
a. Cytotoxic T cells kill target cells at the site
b. Cytokines &histamine released from mast cells
c. CD4+ cells and macrophages
d. B-cells
e. Suppressor T-cells
C
7. A nodule containing phagocytic cells which have undigested foreign matter
(such as micro-organisms), surrounded by lymphocytes and fibroblasts:
a. Lymph nodules
b. Lymph nodes
c. Granuloma
d. Phagosome
e. Phagolysosome
C
8. Patch test is a diagnostic test of:
a. Tuberculoid leprosy
b. Food allergy
c. Lepromatous leprosy
d. Contact dermatitis
e. Chronic granulomatous disease
D
9. Which of the following are involved in the pathogenesis of post streptococcal
glomerulo-nephritis?
a. Antigen-antibody complexes, neutrophil & complement
b. Sensitized T-helper cells to glomerular basement membrane
c. Cytotoxic T-cells reacting with glomerular basement membrane
d. Activated macrophages secreting IL-l, IL-6 & IL-12
A
10. drug-induced type II hypersentivitiy reaction. This reaction may occur if the drug does
which of the following?
a. Activates T cytotoxic cells
b. Acts as a hapten
c. Induces mast cell degranulation, releasing mediators such as histamine, leukotrienes,
and prostaglandins
d. Induces oxygen radical production through the respiratory burst pathway
e. Persists in macrophages
2
MCQ set 2
1. Serum injection may result in the following types of hypersensitivity:
a. Type I
b. Type II
c. Type III
d. A&B
e. A&C
E
2. After injection of anti diphtheritic serum ,patient had severe hypotension,
bronchoconstriction & fainting few minuts after injection – the patient had which type
of hypersensetivity :
a. Type I
b. Type II
c. Type III
d. Type IV
A
3. in serum sickness,patient had hypotension, bronchoconstriction & fainting 24 hours
after serum injection – the patient had which type of hypersensetivity :
a. Type I
b. Type II
c. Type III
d. Type IV
C
4. In skin test for type I hypersensitivity (prick test)
The predicted skin change is:
a. Wheal & flair احمرار وتورم
b. Induration مكان متورم وصلب
c. Ulceration تقرح
d. Non of the above
A
5. In tuberculosis (type IV hypersensitivity) the immune cells involved in the
granuloma formation تكتل من خاليا المناعه حول بكتيريا السل
are the following except:
a. CD4 Th1 cells
b. Macrophages
c. CD8 cytotoxic T cells
d. B lymphocytes
D
1
, Hypersensitivity & autoimmune
MCQ set 2
6. A patient skin tested with PPD to determine previous exposure to M. tuberculosis
develops induration at the skin test. Histologically, the reaction site would most
probably show:
a. Cytotoxic T cells kill target cells at the site
b. Cytokines &histamine released from mast cells
c. CD4+ cells and macrophages
d. B-cells
e. Suppressor T-cells
C
7. A nodule containing phagocytic cells which have undigested foreign matter
(such as micro-organisms), surrounded by lymphocytes and fibroblasts:
a. Lymph nodules
b. Lymph nodes
c. Granuloma
d. Phagosome
e. Phagolysosome
C
8. Patch test is a diagnostic test of:
a. Tuberculoid leprosy
b. Food allergy
c. Lepromatous leprosy
d. Contact dermatitis
e. Chronic granulomatous disease
D
9. Which of the following are involved in the pathogenesis of post streptococcal
glomerulo-nephritis?
a. Antigen-antibody complexes, neutrophil & complement
b. Sensitized T-helper cells to glomerular basement membrane
c. Cytotoxic T-cells reacting with glomerular basement membrane
d. Activated macrophages secreting IL-l, IL-6 & IL-12
A
10. drug-induced type II hypersentivitiy reaction. This reaction may occur if the drug does
which of the following?
a. Activates T cytotoxic cells
b. Acts as a hapten
c. Induces mast cell degranulation, releasing mediators such as histamine, leukotrienes,
and prostaglandins
d. Induces oxygen radical production through the respiratory burst pathway
e. Persists in macrophages
2
