Batch 14 family
االمانة االكاديمية
Hematology exam
1. Prognostic indicators at diagnosis in acute lymphoblastic leukemia include
age and biologic properties of the leukemic blasts which of the following
is another prognostic indicator at diagnosis for ALL:
A. Splenomegaly
B. The presence of down syndrome
C. The presence of ever
D. Initial white blood cell count
E. thrombocytopenia
2. Auer rods are typically seen with which form of leukemia:
A. Acute lymphoblastic leukemia
B. Acute myeloid leukemia
C. Chronic lymphocytic leukemia
D. Chronic myeloid leukemia
E. Hairy cell leukemia
3. A 60 year old male presents with bruising and tiredness.finger breth
splenomegaly and his results reveal :Hb ,wbc count 100*10’9\L,platelet
900*1’9\L>>numerous myelocyte and 4%blast the following is likely to be
present in this patient :
A. Translocation (:21)
B. Deletion chromosome 13
C. Deletion 11q13
D. Normal chromosomal analysis
E. Translocation(9;22)
, 4. A 42-year-old man presented wit tiredness ,breathlessness and nose
bleeds for three weeks .on examination there were several bruises on his
arms and legs ,2cm splenomegaly and fundal hemorrhage .investigation
revealed hb 7.2 g\dl (11’5-16.5), white cell count 13.8 *10 ‘9\L(4-
11)platelet count 24*10’9LL (150-400).white cell predominantly
myeloblast and promyelocyte. Which of the following investigations
would be of most prognostic value:
A. CSF examination
B. Cytochemistry
C. Cytogenic karyotyping
D. Immunophenotyping
E. Bone marrow trephine biopsy
5. Which of the following conditions is most likely to be associated with
thrombocytopenia:
A. Hemophilia A
B. Hereditary hemohrrgic telangectasia
C. Pernicious anaemia
D. Iron deficiency anemia
E. uremia
6. Which of the following ststements concerning abnormalities of the hb
molecules is true:
A. Alpha thalassemia is due to a deficiency of beta chain production
B. HbS is caused by a single base mutation of beta chain
C. Genes for the alpha and beta chains are located on the same
chromosome
D. In thalassemia, persistence of HbF is an adverse prognostic sign
E. Bone marrow examination is the investigation of choice to diagnose
hemoglobinopathy
7. Which of the following patient with Hodgkin has the worst prognosis:
A. 25-year-old man with inguinal lymphadenopathy
B. 25-year-old woman with mediastinal and inguinal lymphadenopathy
C. 25-year-old man with mediastinal and inguinal lymphadenopathy
D. 25-year-old man with cervical and inguinal lymphadenopathy
االمانة االكاديمية
Hematology exam
1. Prognostic indicators at diagnosis in acute lymphoblastic leukemia include
age and biologic properties of the leukemic blasts which of the following
is another prognostic indicator at diagnosis for ALL:
A. Splenomegaly
B. The presence of down syndrome
C. The presence of ever
D. Initial white blood cell count
E. thrombocytopenia
2. Auer rods are typically seen with which form of leukemia:
A. Acute lymphoblastic leukemia
B. Acute myeloid leukemia
C. Chronic lymphocytic leukemia
D. Chronic myeloid leukemia
E. Hairy cell leukemia
3. A 60 year old male presents with bruising and tiredness.finger breth
splenomegaly and his results reveal :Hb ,wbc count 100*10’9\L,platelet
900*1’9\L>>numerous myelocyte and 4%blast the following is likely to be
present in this patient :
A. Translocation (:21)
B. Deletion chromosome 13
C. Deletion 11q13
D. Normal chromosomal analysis
E. Translocation(9;22)
, 4. A 42-year-old man presented wit tiredness ,breathlessness and nose
bleeds for three weeks .on examination there were several bruises on his
arms and legs ,2cm splenomegaly and fundal hemorrhage .investigation
revealed hb 7.2 g\dl (11’5-16.5), white cell count 13.8 *10 ‘9\L(4-
11)platelet count 24*10’9LL (150-400).white cell predominantly
myeloblast and promyelocyte. Which of the following investigations
would be of most prognostic value:
A. CSF examination
B. Cytochemistry
C. Cytogenic karyotyping
D. Immunophenotyping
E. Bone marrow trephine biopsy
5. Which of the following conditions is most likely to be associated with
thrombocytopenia:
A. Hemophilia A
B. Hereditary hemohrrgic telangectasia
C. Pernicious anaemia
D. Iron deficiency anemia
E. uremia
6. Which of the following ststements concerning abnormalities of the hb
molecules is true:
A. Alpha thalassemia is due to a deficiency of beta chain production
B. HbS is caused by a single base mutation of beta chain
C. Genes for the alpha and beta chains are located on the same
chromosome
D. In thalassemia, persistence of HbF is an adverse prognostic sign
E. Bone marrow examination is the investigation of choice to diagnose
hemoglobinopathy
7. Which of the following patient with Hodgkin has the worst prognosis:
A. 25-year-old man with inguinal lymphadenopathy
B. 25-year-old woman with mediastinal and inguinal lymphadenopathy
C. 25-year-old man with mediastinal and inguinal lymphadenopathy
D. 25-year-old man with cervical and inguinal lymphadenopathy
