Chapter 09: Drug Therapy for Central Nervous System Problems Visovsky: Introduction to Clinical Pharmacology, 9th Edition A GRADED

MULTIPLE CHOICE 1. Which neurotransmitter has an inhibitory action within the central nervous system? a. Epinephrine b. Acetylcholine c. Norepinephrine d. Gamma-aminobutyric acid ANS: D Neurotransmitters can be excitatory or inhibitory. Excitatory neurotransmitters include acetylcholine (Ach), epinephrine, and norepinephrine. Inhibitory neurotransmitters include dopamine, some types of serotonin, and GABA (gamma-aminobutyric acid). DIF: Cognitive Level: Knowing REF: p. 159 2. How does the drug tolcapone relieve the symptoms of Parkinson disease? a. Acts as a dopamine agonist, replacing the activity of dopamine b. Forces the substantia nigra to increase the production and release of natural dopamine c. Suppresses the activity of an enzyme that normally breaks down naturally occurring dopamine d. Increases the number of dopamine receptors sites throughout the central nervous system, thus increasing the effectiveness of dopamine and dopamine agonists ANS: C