Chapter 10: Drug Therapy for Mental Health Visovsky: Introduction to Clinical Pharmacology, 9th Edition

Which drug category is useful in promoting sleep among patients with insomnia? a. Sedatives b. ACE inhibitors c. Atypical antipsychotics d. Selective serotonin reuptake inhibitors ANS: A Sedatives are drugs that have the main purpose of promoting sleep by changing signals in the central nervous system and reducing responses to stimulation. DIF: Cognitive Level: Knowing REF: p. 184 2. You are preparing to give the benzodiazepine Valium to a patient as a premedication before surgery. The patient asks you how this drug works. What is your best response? a. “This drug works by binding to receptors acting with GABA to induce sleep.” b. “This drug is acts by preventing binding to the benzodiazepine receptors.” c. “This drug acts by inhibiting GABA responses to relax muscles.” d. “This drug acts by binding to opioid receptors.” ANS: A Benzodiazepines are sedating hypnotic drugs that depress the CNS by binding to benzodiazepine (BNZ) receptors that act with gamma-aminobutyric acid (GABA) receptors to enhance GABA effects, resulting sleep and muscle relaxation.