TEST BANK FOR TIETZ
FUNDAMENTALS OFCLINICAL
CHEMISTRY AND MOLECULAR
DIAGNOSTICS 7TH EDITION BY
BURTIS
,TABLE OF CONTENTS:
I. PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical
Techniques
3. Clinical Evaluation of Methods
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques
10. Electrochemistry and Chemical Sensors
11. Electrophoresis
12. Chromatography
13. Mass Spectrometry
14. Enzyme and Rate Analyses
15. Immunochemical Techniques16
Automation
17. Point-of-Care Instrumentation
III. ANALYTES
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
,22. Carbohydrates
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Fac-tors
24. Electrolytes and Blood Gases
25. Hormones
26. Catecholamines and Serotonin
27. Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias
30. Therapeutic Drugs and Their Management
31. Clinical Toxicology
32. Toxic Metals
IV. PATHOPHYSIOLOGY
33. Diabetes
34. Cardiovascular Disease
35. Kidney Disease
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base
Metabolism
37. Liver Disease
38. Gastrointestinal and Pancreatic Diseases
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex
42. Thyroid Disorders
43. Reproduction-Related Disorders
44. Pregnancy and Prenatal Testing
45. Newborn Screening and Inborn Errors of Metabolism
46. Pharmacogenetics
V. MOLECULAR DIAGNOSTICS NEW!
47. Principles of Molecular Biology
48. Nucleic Acid Techniques and Applications
49. Genomes and Nucleic Acid Alterations
VI. REFERENCE INFORMATION
50. Reference Information for the Clinical Laboratory
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Test Bank
MULTIPLE CHOICE
1. An individual working in a clinical chemistry laboratory is married to a sales representative
who works for a company that sells chemistry laboratory supplies. When the laboratory
manager requests a list of needed supplies, cost of supplies, and vendors, this individual only
recommends the spouse’s company as the vendor. This is considered to be a(n):
a. accounting issue.
b. possible conflict of interest.
c. maintenance of confidentiality issue.
d. problem with resource allocation.
ANS: B
Concern has been raised over the interrelationships between practitioners in the medical field
and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
Similarly, relationships have been scrutinized between clinical laboratorians and
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
National Institutes of Health (NIH) in 1995 to require official institutional review of financial
disclosure by researchers and management of situations in which disclosure indicates potential
conflicts of interest.
DIF: 1 REF: Page 4-5 OBJ: 6 | 7
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the
pain following her recent surgery. A friend of the patient claims that the same painkiller
“worked wonders” to reduce her pain after the same surgery. The physician states that the
difference in the effect of the drug might be caused by , which is studied in
pharmacogenetics.
a. epidemiology
b. an inherited disease
c. a conflict of interest
d. a genetic variation in drug-metabolizing enzymes
ANS: D
Pharmacogenetics is the study of the genetic variation of drug metabolism between
individuals.
DIF: 1 REF: Page 3 OBJ: 1
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
name of a close friend printed on the bar-coded label. The genetic test that is ordered on the
friend’s sample would provide diagnostic information about a disorder that has a poor
prognosis, and the test is usually performed by John. He asks a fellow employee to analyze
the sample for him and not divulge the results. This ethical issue concerns:
a. confidentiality of patient genetic and medical information.
b. a conflict of interest.
FUNDAMENTALS OFCLINICAL
CHEMISTRY AND MOLECULAR
DIAGNOSTICS 7TH EDITION BY
BURTIS
,TABLE OF CONTENTS:
I. PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical
Techniques
3. Clinical Evaluation of Methods
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques
10. Electrochemistry and Chemical Sensors
11. Electrophoresis
12. Chromatography
13. Mass Spectrometry
14. Enzyme and Rate Analyses
15. Immunochemical Techniques16
Automation
17. Point-of-Care Instrumentation
III. ANALYTES
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
,22. Carbohydrates
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Fac-tors
24. Electrolytes and Blood Gases
25. Hormones
26. Catecholamines and Serotonin
27. Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias
30. Therapeutic Drugs and Their Management
31. Clinical Toxicology
32. Toxic Metals
IV. PATHOPHYSIOLOGY
33. Diabetes
34. Cardiovascular Disease
35. Kidney Disease
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base
Metabolism
37. Liver Disease
38. Gastrointestinal and Pancreatic Diseases
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex
42. Thyroid Disorders
43. Reproduction-Related Disorders
44. Pregnancy and Prenatal Testing
45. Newborn Screening and Inborn Errors of Metabolism
46. Pharmacogenetics
V. MOLECULAR DIAGNOSTICS NEW!
47. Principles of Molecular Biology
48. Nucleic Acid Techniques and Applications
49. Genomes and Nucleic Acid Alterations
VI. REFERENCE INFORMATION
50. Reference Information for the Clinical Laboratory
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Test Bank
MULTIPLE CHOICE
1. An individual working in a clinical chemistry laboratory is married to a sales representative
who works for a company that sells chemistry laboratory supplies. When the laboratory
manager requests a list of needed supplies, cost of supplies, and vendors, this individual only
recommends the spouse’s company as the vendor. This is considered to be a(n):
a. accounting issue.
b. possible conflict of interest.
c. maintenance of confidentiality issue.
d. problem with resource allocation.
ANS: B
Concern has been raised over the interrelationships between practitioners in the medical field
and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
Similarly, relationships have been scrutinized between clinical laboratorians and
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
National Institutes of Health (NIH) in 1995 to require official institutional review of financial
disclosure by researchers and management of situations in which disclosure indicates potential
conflicts of interest.
DIF: 1 REF: Page 4-5 OBJ: 6 | 7
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce the
pain following her recent surgery. A friend of the patient claims that the same painkiller
“worked wonders” to reduce her pain after the same surgery. The physician states that the
difference in the effect of the drug might be caused by , which is studied in
pharmacogenetics.
a. epidemiology
b. an inherited disease
c. a conflict of interest
d. a genetic variation in drug-metabolizing enzymes
ANS: D
Pharmacogenetics is the study of the genetic variation of drug metabolism between
individuals.
DIF: 1 REF: Page 3 OBJ: 1
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
name of a close friend printed on the bar-coded label. The genetic test that is ordered on the
friend’s sample would provide diagnostic information about a disorder that has a poor
prognosis, and the test is usually performed by John. He asks a fellow employee to analyze
the sample for him and not divulge the results. This ethical issue concerns:
a. confidentiality of patient genetic and medical information.
b. a conflict of interest.
