Summary Need help understanding the cell cycle and its inner workings, this diagram has all the information you need

Activation
Of Cell Cycle
factor




É
e EGF
g


via trans
phosphorylation
GDPREPLACED
MEMBRANE dueto conformational with atPantate
change Ras
Mitogenactivated
Fave Ras GTP
Protein kinase
MAPR




N_t
g



MEMBRANE
MY gene
y leadto increased
M DNA

EÉT Éj
genesthat
havemany



t
affectssuch
as raisingCD Dkk
repressthe r was



j
expressionofthe phosphorylation
of

j
Plocases itand
GainE 4E2FH todissociate
mono fromthegene
p hosphorylation reducingtheinhibition
ofits transcription




Janeane
bindtoCyclonegeneto
and
agee
beg Toform hyperphosphorylates RB
tofullyinactivate
Cellcycle progresses it leadingto the
towards the hills OO g ofElf's
activation



writ OO
E cPk2
Cyclin
of
expression cyclinE
formingapositive