Phar 1821 (2022) week 6 lecture note
Week 6 – Skin health #1
LO 1. To refresh basic skin anatomy & corresponding issues
2. To gain basic knowledge of appropriate skin and hair products for
competence advising patients
3. To further understand aspects of skincare and products such as scars,
sun care issues
4. To introduce first aid around burns, bites, and stings
5. To gain insight into issues around young and elderly individuals
Skin anatomy - Flexible layer that protects what’s in
o Protection from water, air, pathogens
- The largest organ in the body
- Complex structure
- Multiple functions
- Keeps internal environment stable
- Large volume of presentations to pharmacists (20%) and GPs (15%)
(Marks et al 1999)
- Includes hair & nail conditions
Epidermis,
dermis,
subcutaneous
layers
Epidermis - Outer thin layer of varying thickness
- Prevents water loss, protects
- Pigment protects from UV radiation (melanocytes)
- Keratinocytes formed constantly & migrate to surface (4 weeks) then
shed (i.e., dust in your house)
, Dermis -Connective tissue – collagen (strength) & elastin (flexibility) protein
network (extracellular matrix)
- Contains blood vessels, lymph vessels, nerves, hair follicles, sweat
glands, and muscle
o Mostly, this is where the medicaments are absorbed due to
the presence of these
o This is where the pharmacological agents are absorbed
o From the epidermis to the dermis, the pharmacological
agents are absorbed, then in the dermis, to the vessels
o The vessels = circulatory supply – distribution of the
medication
Subcutaneous - Protection & insulation
(hypodermis) - Collagen fibres, fat cells
o Are the two things that change with aging
o As you get older, the number of fat cells & collagen fibres
decrease
- Blood vessels & nerves
Hair, Structures that are within the skin
Sebaceous
glands, Sweat Hair - Primary role – protection
glands o But it has sensory role as well; movement
of the hair and the muscle in the hair also
provides sensory nervous stimuli – imp for
our protection role
- Sebum producing hair follicle – to protect &
strengthen the hair shaft from damage
o Excess sebum/under-producing sebum =>
can cause dysfunction within skin
- Attached to the arrector pili smooth muscle
Sebaceous - Found in large numbers in face, upper back, and
Glands chest
- Become large & active during the hormonal
changes of puberty
Sweat Glands - Apocrine glands
o Located in the axilla (armpit) and begin to
function at puberty
o As part of the change in the endocrine
system, the originally inactive form of the
apocrine became activated as puberty
begins
- Eccrine glands
o All over the body
Week 6 – Skin health #1
LO 1. To refresh basic skin anatomy & corresponding issues
2. To gain basic knowledge of appropriate skin and hair products for
competence advising patients
3. To further understand aspects of skincare and products such as scars,
sun care issues
4. To introduce first aid around burns, bites, and stings
5. To gain insight into issues around young and elderly individuals
Skin anatomy - Flexible layer that protects what’s in
o Protection from water, air, pathogens
- The largest organ in the body
- Complex structure
- Multiple functions
- Keeps internal environment stable
- Large volume of presentations to pharmacists (20%) and GPs (15%)
(Marks et al 1999)
- Includes hair & nail conditions
Epidermis,
dermis,
subcutaneous
layers
Epidermis - Outer thin layer of varying thickness
- Prevents water loss, protects
- Pigment protects from UV radiation (melanocytes)
- Keratinocytes formed constantly & migrate to surface (4 weeks) then
shed (i.e., dust in your house)
, Dermis -Connective tissue – collagen (strength) & elastin (flexibility) protein
network (extracellular matrix)
- Contains blood vessels, lymph vessels, nerves, hair follicles, sweat
glands, and muscle
o Mostly, this is where the medicaments are absorbed due to
the presence of these
o This is where the pharmacological agents are absorbed
o From the epidermis to the dermis, the pharmacological
agents are absorbed, then in the dermis, to the vessels
o The vessels = circulatory supply – distribution of the
medication
Subcutaneous - Protection & insulation
(hypodermis) - Collagen fibres, fat cells
o Are the two things that change with aging
o As you get older, the number of fat cells & collagen fibres
decrease
- Blood vessels & nerves
Hair, Structures that are within the skin
Sebaceous
glands, Sweat Hair - Primary role – protection
glands o But it has sensory role as well; movement
of the hair and the muscle in the hair also
provides sensory nervous stimuli – imp for
our protection role
- Sebum producing hair follicle – to protect &
strengthen the hair shaft from damage
o Excess sebum/under-producing sebum =>
can cause dysfunction within skin
- Attached to the arrector pili smooth muscle
Sebaceous - Found in large numbers in face, upper back, and
Glands chest
- Become large & active during the hormonal
changes of puberty
Sweat Glands - Apocrine glands
o Located in the axilla (armpit) and begin to
function at puberty
o As part of the change in the endocrine
system, the originally inactive form of the
apocrine became activated as puberty
begins
- Eccrine glands
o All over the body
