TCA & carbohydrates
1-The steps of glycolysis between glyceraldehyde 3-phosphate and 3-phosphoglycerate involve all
of the following EXCEPT
a. ATP synthesis
.b. utilization of Pi
.+c. oxidation of NADH to NAD
.d. reduction of NAD+ to NADH
.e. formation of 1,3 bisphosphoglycerate
2-When a muscle contracts aerobically, less lactic acid is formed than when it contracts .
anaerobically because under aerobic conditions
.a. muscles cannot convert glucose 6-phosphate to pyruvate
.b. most of the pyruvate generated is oxidized
.c. the lactic acid generated is rapidly converted back to glucose
.d. the major source of energy is the pentose pathway
.e. the major source of energy is creatine phosphate
3-The conversion of 1 mol of glucose 1-phosphate to 2 mol of pyruvate by the glycolytic pathway .
results in a net formation of
.a. 1 mol of NAD+ and 2 mol of ATP
.b. 1 mol of NADH and 2 mol of ATP
.c. 2 mol of NADH and 2 mol of ATP
.d. 2 mol of NADH and 3 mol of ATP
.e. 2 mol of NAD+ and 3 mol of ATP
4- Which combination of cofactors is involved in the conversion of pyruvate to acetyl-CoA .
a. NAD+, biotin, and TPP
+b. TPP, lipoic acid, and NAD
c. pyridoxal phosphate, FAD, and lipoic acid
d. biotin, FAD, and TPP
e. biotin, NAD+, and FAD
5-The conversion of 1 mol of pyruvate to 3 mol of CO2 via pyruvate dehydrogenase and the citric
.)acid cycle yields ___mol of NADH, ____mol of FADH2, and ___mol of ATP (or GTP
, a. 3; 2; 0
b. 4; 2; 1
c. 4; 1; 1
d. 3; 1; 1
e. 2; 2; 2
6-An enzymatic reaction that is most similar to the conversion of pyruvate to acetyl CoA is .
catalyzed by
.a. citrate synthase
.b. alpha-ketoglutarate dehydrogenase
.c. succinyl-CoA synthetase
.d. isocitrate dehydrogenase
.e. succinate dehydrogenase
7-Intermediates of the citric acid cycle are replenished by a reaction converting pyruvate to .
.a. oxaloacetate
.b. citrate
.c. alpha-ketoglutarate
.d. succinyl-CoA
.e. acetyl-CoA
8-Which enzyme is used in gluconeogenesis but not glycolysis .
a. Phosphoglucoisomerase
b. Lactate dehydrogenase
c. Glucose 6-phosphatase
d. 3-Phosphoglycerate kinase
e. Aldolase
9-All of the following compounds can serve as the starting material for the synthesis of glucose via
gluconeogenesis EXCEPT
.a. alanine
.b. oleic acid
.c. aspartic acid
.d. glycerol
1-The steps of glycolysis between glyceraldehyde 3-phosphate and 3-phosphoglycerate involve all
of the following EXCEPT
a. ATP synthesis
.b. utilization of Pi
.+c. oxidation of NADH to NAD
.d. reduction of NAD+ to NADH
.e. formation of 1,3 bisphosphoglycerate
2-When a muscle contracts aerobically, less lactic acid is formed than when it contracts .
anaerobically because under aerobic conditions
.a. muscles cannot convert glucose 6-phosphate to pyruvate
.b. most of the pyruvate generated is oxidized
.c. the lactic acid generated is rapidly converted back to glucose
.d. the major source of energy is the pentose pathway
.e. the major source of energy is creatine phosphate
3-The conversion of 1 mol of glucose 1-phosphate to 2 mol of pyruvate by the glycolytic pathway .
results in a net formation of
.a. 1 mol of NAD+ and 2 mol of ATP
.b. 1 mol of NADH and 2 mol of ATP
.c. 2 mol of NADH and 2 mol of ATP
.d. 2 mol of NADH and 3 mol of ATP
.e. 2 mol of NAD+ and 3 mol of ATP
4- Which combination of cofactors is involved in the conversion of pyruvate to acetyl-CoA .
a. NAD+, biotin, and TPP
+b. TPP, lipoic acid, and NAD
c. pyridoxal phosphate, FAD, and lipoic acid
d. biotin, FAD, and TPP
e. biotin, NAD+, and FAD
5-The conversion of 1 mol of pyruvate to 3 mol of CO2 via pyruvate dehydrogenase and the citric
.)acid cycle yields ___mol of NADH, ____mol of FADH2, and ___mol of ATP (or GTP
, a. 3; 2; 0
b. 4; 2; 1
c. 4; 1; 1
d. 3; 1; 1
e. 2; 2; 2
6-An enzymatic reaction that is most similar to the conversion of pyruvate to acetyl CoA is .
catalyzed by
.a. citrate synthase
.b. alpha-ketoglutarate dehydrogenase
.c. succinyl-CoA synthetase
.d. isocitrate dehydrogenase
.e. succinate dehydrogenase
7-Intermediates of the citric acid cycle are replenished by a reaction converting pyruvate to .
.a. oxaloacetate
.b. citrate
.c. alpha-ketoglutarate
.d. succinyl-CoA
.e. acetyl-CoA
8-Which enzyme is used in gluconeogenesis but not glycolysis .
a. Phosphoglucoisomerase
b. Lactate dehydrogenase
c. Glucose 6-phosphatase
d. 3-Phosphoglycerate kinase
e. Aldolase
9-All of the following compounds can serve as the starting material for the synthesis of glucose via
gluconeogenesis EXCEPT
.a. alanine
.b. oleic acid
.c. aspartic acid
.d. glycerol
