60 MCQ HTN, ISHD, Dyslipidemia
1. Nitric oxide is NOT involved in the vasodilator effect of
a) Nitrates
b) Nitroprusside
c) Carvedilol
d) Nebivolol
e) C & d
2. A nitric oxide donor that may induce cyanide toxicity
a) Nitrates
b) Nitroprusside
c) Nicardipine
d) A and B
3. All the following are indications of nitrates except
a) Right ventricular infarction.
b) CHF & acute pulmonary edema.
c) Angina & acute myocardial infarction
d) Hypertensive emergencies.
4. The following is (are) WRONG
a) Trimetazidine is an antianginal that increases myocardial glucose metabolism
b) Ivabradine is an antianginal that selectively inhibits pacemaker If current
c) Ranolazine Increase late inward Na+ current
d) Tolerance to nitrates is avoided by allowing an 8 hr/day nitrate free period
5. Nitrates reduce work done by heart in angina mainly through
a) Reducing heart rate
b) Redistribution of blood to subendocardial ischemic areas
c) Vasodilation of stenosed large epicardial coronary arteries & collaterals
d) Vasodilation of venules with reduction of venous return & preload
6. Long acting nitrate preparation with no 1st pass hepatic metabolism
a) Nitroglycerin
b) Isosorbide dinitrate
c) Isosorbide mononitrate
d) B or C
7. Nitrate preparation used for termination of an acute attack of angina
a) Nitroglycerin
b) Isosorbide dinitrate
c) Isosorbide mononitrate
d) A or B
, 8. Reduction of heart rate by beta blockers in angina do not
a) Blunts the increase in heart rate & blood pressure during exercise
b) Controls heart rate at rest (50- 60 /min)
c) Decreases diastolic period resulting in increased coronary filling in diastole
d) Reduces reflex tachycardia and worsening of angina by nitrates
9. Worsening of anginal pain may result from all of the following except:
a) Abruptly stopping nitrates
b) Reflex tachycardia caused by nitrates
c) Administration of beta blockers in vasospastic angina
d) Administration of beta blockers with intrinsic sympathomimetic activity
e) Administration of amlodipine in Prinzmetal’s angina
10.Drug of choice in hypertrophic obstructive cardiomyopathy:
a) Verapamil
b) Digoxin
c) Nitrates
d) Amlodipine
11. Nitrates & nifedipine share all the following adverse reactions except
a) Headache & flushing
b) Hypotension
c) Reflex tachycardia
d) Ankle edema
12. Hypotension, heart failure, bradycardia & heart block are side effects of
a) Verapamil
b) Nifedipine
c) Amlodipine
d) Nicardipine
13.Beta blockers & calcium channel blockers do NOT share the following indication
a) Angina
b) Hypertension
c) Supra ventricular arrhythmia
d) Peripheral vascular diseases
14.The main mechanism of antihypertensive action of beta blockers is
a) Negative inotropic & chronotropic effects
b) Suppression of renin release
c) Resetting of baroreceptors
d) Central & peripheral sympatholytic effect
1. Nitric oxide is NOT involved in the vasodilator effect of
a) Nitrates
b) Nitroprusside
c) Carvedilol
d) Nebivolol
e) C & d
2. A nitric oxide donor that may induce cyanide toxicity
a) Nitrates
b) Nitroprusside
c) Nicardipine
d) A and B
3. All the following are indications of nitrates except
a) Right ventricular infarction.
b) CHF & acute pulmonary edema.
c) Angina & acute myocardial infarction
d) Hypertensive emergencies.
4. The following is (are) WRONG
a) Trimetazidine is an antianginal that increases myocardial glucose metabolism
b) Ivabradine is an antianginal that selectively inhibits pacemaker If current
c) Ranolazine Increase late inward Na+ current
d) Tolerance to nitrates is avoided by allowing an 8 hr/day nitrate free period
5. Nitrates reduce work done by heart in angina mainly through
a) Reducing heart rate
b) Redistribution of blood to subendocardial ischemic areas
c) Vasodilation of stenosed large epicardial coronary arteries & collaterals
d) Vasodilation of venules with reduction of venous return & preload
6. Long acting nitrate preparation with no 1st pass hepatic metabolism
a) Nitroglycerin
b) Isosorbide dinitrate
c) Isosorbide mononitrate
d) B or C
7. Nitrate preparation used for termination of an acute attack of angina
a) Nitroglycerin
b) Isosorbide dinitrate
c) Isosorbide mononitrate
d) A or B
, 8. Reduction of heart rate by beta blockers in angina do not
a) Blunts the increase in heart rate & blood pressure during exercise
b) Controls heart rate at rest (50- 60 /min)
c) Decreases diastolic period resulting in increased coronary filling in diastole
d) Reduces reflex tachycardia and worsening of angina by nitrates
9. Worsening of anginal pain may result from all of the following except:
a) Abruptly stopping nitrates
b) Reflex tachycardia caused by nitrates
c) Administration of beta blockers in vasospastic angina
d) Administration of beta blockers with intrinsic sympathomimetic activity
e) Administration of amlodipine in Prinzmetal’s angina
10.Drug of choice in hypertrophic obstructive cardiomyopathy:
a) Verapamil
b) Digoxin
c) Nitrates
d) Amlodipine
11. Nitrates & nifedipine share all the following adverse reactions except
a) Headache & flushing
b) Hypotension
c) Reflex tachycardia
d) Ankle edema
12. Hypotension, heart failure, bradycardia & heart block are side effects of
a) Verapamil
b) Nifedipine
c) Amlodipine
d) Nicardipine
13.Beta blockers & calcium channel blockers do NOT share the following indication
a) Angina
b) Hypertension
c) Supra ventricular arrhythmia
d) Peripheral vascular diseases
14.The main mechanism of antihypertensive action of beta blockers is
a) Negative inotropic & chronotropic effects
b) Suppression of renin release
c) Resetting of baroreceptors
d) Central & peripheral sympatholytic effect
