pathophysiology the biologic basis for disease in adult and children

1. Discuss genetic testing and its implications. When might you recommend genetic testing? - 1. Discuss genetic testing and its implications. When might you recommend genetic testing? - 1.What is the role of the cell membrane - Express self-antigens to prevent auto-immune responses & Control the intercellular environment 2. What does dizygotic mean and why is this important to understand when looking at genetic vs. epigenetic causes of a pathology? - 2. What happens if mRNA is genetically damaged? - Potential for coded protein to be damaged 3. What would happen if the Endoplasmic Reticulum was damaged? - proteins could be malformed, rejected, or not sent to Golgi Apparatus, causing multiple pathologies without the ER or genetically altered ER. The Endoplasmic Reticulum (ER) supports homeostasis in the cell and subsequently in the body. It is the organelle responsible for folding newly synthesized proteins before they are exported to the Golgi Apparatus for packing and shipping. Another important function of the ER is helping to regulate the calcium-ROS balance. Lipid biosynthesis is a third role the ER plays in the cell.