Question 1 (IMMUNOLOGY)
A 6-year-old boy experienced severe reactions to a briefly baked egg but tolerates oven baked
cakes that contain egg. Which of the following is most likely to be true?
He has an allergic reaction to the butter used to bake the egg.
He has an increased ovalbumin specific IgE.
The heating and Maillard reaction during baking cakes does NOT abrogate IgE binding to the egg proteins for this person.
He has an increased IgE level that is specific for ovomucoid.
Question 2
Why can most celiac disease patients tolerate oat but not barley?
Because the barley has many prolines and glutamine residues in the gliadin protein.
Because oat-specific T cells produce Th2 cytokines
Because oat avenin is quite different form barley gliadin and glutenin
Because tTG cannot deamidate oat proteins
Question 3
Which of the following cytokines induces isotype switching in B cells to the production of IgE
antibodies?
IL-4
Il-10
IL-17
IL-5
Question 4
Antigen presenting cells that activate helper T cells must express which one of the following on
their surfaces?
IgE
Gamma interferon
Class I MHC antigen
Class II MHC antigens
Question 5
Which of the following regarding the high affinity IgE receptor FceRI is true?
This receptor is expressed on neutrophils when they leave the blood stream
The receptor is present on basophils in the blood circulation
The receptor is present on those B cells that produce IgE antibodies
The receptor expression is induced on mast cells ONLY in the presence of the allergen
Question 6
All of the following are released by mast cells at degranulation, except
Histamine
Prostaglandins
IgE antibodies
, Leukotrienes
Question 7
Can microbiota influence the development of allergies?
Yes, because they compromise intestinal barrier function.
No, because they promote Th2 development.
Yes, when they produce short chain fatty acids.
No, when they ferment proteins.
Question 8
Anti IgE treatment with Xolair/Omalizumab can:
Crosslink IgE that is bound to FceRI.
Block binding of IgE to FceRI.
Induce allergen-specific IgG antibody responses.
All of the above.
Question 9
Which of these statements on lactose intolerance is not correct?
Lactose intolerance is more prevalent in Asia than in Europe.
Lactose intolerant individuals can never express functional lactase.
You can consume moderate portions of cheese and yoghurt (and even a bit of milk) when you are lactose intolerant.
Lactose malabsorption contributes to the symptoms of lactase intolerance.
Question 10
Which of the following clinical descriptions is most likely to represent a food allergy?
A 3-year old child experiences acute vomiting minutes after she ingests, on separate occasions spicy potato chips and sour c
A breast fed 5-month old infant experiences severe vomiting, lethargy, and an increased white blood cell count 2 hours after
An 18-year old experiences cramps and diarrhea at one hour after ingesting a large milk shake.
A 47-year old experiences facial flushing and a tingling sensation in the mouth after ingesting tuna in a restaurant. He previ
Question 11
A child stung by a bee experiences respiratory distress within minutes and lapses into
unconsciousness. This reaction is probably mediated by
IgE antibody
IgG antibody
Sensitized T-cells
Complement
Question 12
Which of the following methods of controlling exposure to cat allergen is most useful
Keep the cat out of the bedroom.
Dispose of the cat.
A 6-year-old boy experienced severe reactions to a briefly baked egg but tolerates oven baked
cakes that contain egg. Which of the following is most likely to be true?
He has an allergic reaction to the butter used to bake the egg.
He has an increased ovalbumin specific IgE.
The heating and Maillard reaction during baking cakes does NOT abrogate IgE binding to the egg proteins for this person.
He has an increased IgE level that is specific for ovomucoid.
Question 2
Why can most celiac disease patients tolerate oat but not barley?
Because the barley has many prolines and glutamine residues in the gliadin protein.
Because oat-specific T cells produce Th2 cytokines
Because oat avenin is quite different form barley gliadin and glutenin
Because tTG cannot deamidate oat proteins
Question 3
Which of the following cytokines induces isotype switching in B cells to the production of IgE
antibodies?
IL-4
Il-10
IL-17
IL-5
Question 4
Antigen presenting cells that activate helper T cells must express which one of the following on
their surfaces?
IgE
Gamma interferon
Class I MHC antigen
Class II MHC antigens
Question 5
Which of the following regarding the high affinity IgE receptor FceRI is true?
This receptor is expressed on neutrophils when they leave the blood stream
The receptor is present on basophils in the blood circulation
The receptor is present on those B cells that produce IgE antibodies
The receptor expression is induced on mast cells ONLY in the presence of the allergen
Question 6
All of the following are released by mast cells at degranulation, except
Histamine
Prostaglandins
IgE antibodies
, Leukotrienes
Question 7
Can microbiota influence the development of allergies?
Yes, because they compromise intestinal barrier function.
No, because they promote Th2 development.
Yes, when they produce short chain fatty acids.
No, when they ferment proteins.
Question 8
Anti IgE treatment with Xolair/Omalizumab can:
Crosslink IgE that is bound to FceRI.
Block binding of IgE to FceRI.
Induce allergen-specific IgG antibody responses.
All of the above.
Question 9
Which of these statements on lactose intolerance is not correct?
Lactose intolerance is more prevalent in Asia than in Europe.
Lactose intolerant individuals can never express functional lactase.
You can consume moderate portions of cheese and yoghurt (and even a bit of milk) when you are lactose intolerant.
Lactose malabsorption contributes to the symptoms of lactase intolerance.
Question 10
Which of the following clinical descriptions is most likely to represent a food allergy?
A 3-year old child experiences acute vomiting minutes after she ingests, on separate occasions spicy potato chips and sour c
A breast fed 5-month old infant experiences severe vomiting, lethargy, and an increased white blood cell count 2 hours after
An 18-year old experiences cramps and diarrhea at one hour after ingesting a large milk shake.
A 47-year old experiences facial flushing and a tingling sensation in the mouth after ingesting tuna in a restaurant. He previ
Question 11
A child stung by a bee experiences respiratory distress within minutes and lapses into
unconsciousness. This reaction is probably mediated by
IgE antibody
IgG antibody
Sensitized T-cells
Complement
Question 12
Which of the following methods of controlling exposure to cat allergen is most useful
Keep the cat out of the bedroom.
Dispose of the cat.
