non steroidal anti-inflammatory drugs

Non steroidal anti-inflammatory drugs

i. Non selective Cox ( cyclo oxygenase) inhibitors) / Traditional non-steroidal anti-inflammatory
drugs
1) Salicylates
E.g.:- Aspirin
2) Propionic Acid derivatives
E.g.:- Ketoprofen, naproxen, ibuprofen
3) Anthranilic acid derivatives
E.g.:- Mephenamic acid
4) Aryl acetic acid derivatives
E.g.:- Diclofenac, Aceclofenac
5) Oxicam derivatives
E.g.:- Piroxicam, Tenoxicam
6) Pyrrolo pyrrole derivatives
E.g.:- Ketorolac
7) Indole derivatives
E.g.:- Indomethacin
8) Pyrozolone derivatives
E.g.:- Phenylbutazone


ii. Preferential cox 2 inhibitors
E.g.:- Nimesulide, Nabumetone
Nimesulide is more safe.


iii. Selective Cox 2 inhibitors
E.g.:- Valdecoxib, Rofecoxib, Etoricoxib, Parecoxib, Celecoxib


iv. Analgesic antipyretics with poor anti-inflammatory action
E.g.:- Paracetamol, Nefopam




Reference From my lecture notes.