BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
Multiple Choice
1. TB 11.001 Who was the first to report that certain rare inherited diseases were caused by the absence
of specific enzymes?
a. Charles Darwin
b. Archibald Garrod
c. George Beadle
d. Vernon Ingram
e. James Watson
Ans: B
Feedback: 11.1
Difficulty: Easy
2. TB 11.002 Alcaptonuria is a genetic disease that is characterized by .
a. urine turning dark upon exposure to the air
b. mental retardation
c. paralysis
d. urine smelling and tasting like maple syrup
e. high fevers
Ans: A
Feedback: 11.1
Difficulty: Easy
3. TB 11.003 An alcaptonuric lacks the enzyme that oxidizes what metabolite?
a. phenylalanine
b. tyrosine
c. homogentisic acid
d. asparagine
e. pantothenic acid
Ans: C
Feedback: 11.1
Difficulty: Easy
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
,BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
4. TB 11.004 What did Archibald Garrod call diseases like alcaptonuria?
a. deadly diseases
b. inborn errors of transcription
c. homogentisms
d. errors
e. inborn errors of metabolism
Ans: E
Feedback: 11.1
Difficulty: Easy
6. TB 11.005 What did Beadle and Tatum use to generate mutations in their experimental organism? a.
mustard gas
b. irradiation
c. fluorescent dyes
d. ethidium bromide
e. Coomassie blue
Ans: B
Feedback: 11.1
Difficulty: Easy
7. TB 11.006 Beadle and Tatum's research suggested that .
a. a gene carries the information to build lipids.
b. a gene carries the information to build carbohydrates.
c. a gene carries the information for the construction of a particular enzyme
d. a gene is made of RNA
e. a gene is made of DNA
Ans: C
Feedback: 11.1
Difficulty: Medium
8. TB 11.007 Beadle and Tatum's original hypothesis had to be changed when it was discovered that some
enzymes were composed of more than one polypeptide chain?
a. the One Gene – One Enzyme hypothesis
b. the One Gene – One Polypeptide hypothesis
c. the One Polypeptide – One Enzyme hypothesis
d. the One Polypeptide – One Gene hypothesis
e. the One Gene – Two Gene
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
,BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
hypothesis Ans: B
Feedback: 11.1
Difficulty: Easy
9. TB 11.008 Why has the One Gene – One Polypeptide hypothesis had to be modified?
a. It was totally wrong.
b. Genes can be spliced differently to generate a variety of related polypeptides.
c. Enzymes sometimes consist of more than one polypeptide, each of which is coded for by its own gene.
d. Enzymes actually code for genes.
e. Polypeptides code for genes.
Ans: B
Feedback: 11.1
Difficulty: Medium
10.TB 11.009 Which scientist is best known for his work on sickle cell anemia and proving the
mechanism that causes the disease?
a. Charles Darwin
b. Archibald Garrod
c. George Beadle
d. Vernon Ingram
e. James Watson
Ans: D
Feedback: 11.1
Difficulty: Easy
11.TB 11.010 What difference between sickle cell and normal hemoglobin is apparently responsible for
all of the symptoms associated with sickle cell anemia?
a. The difference is a valine substitution in the mutant sickle cell hemoglobin for a glutamic
acid in the normal molecule.
b. The difference is a glutamic acid substitution in the mutant sickle cell hemoglobin for a
valine in the normal molecule.
c. The sickle cell hemoglobin is longer.
d. The sickle cell hemoglobin is shorter.
Ans: A
Feedback: 11.1
Difficulty: Hard
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
, BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
13. TB 11.011 What is the process by which complementary RNAs are synthesized from a DNA template?
a. translation
b. transcription
c. protein synthesis
d. transduction
e. transliteration
Ans: B
Feedback: 11.1
Difficulty: Easy
15. TB 11.012 What is the name of the process through which the code stored in mRNAs is converted
into polypeptides?
a. translation
b. transcription
c. transformation
d. transduction
e. transliteration
Ans: A
Feedback: 11.1
Difficulty: Easy
16. TB 11.013 What is the name of the molecular machine that translates the code stored in mRNAs?
a. lysosomes
b. endosomes
c. ribosomes
d. ribotomes
e. microsomes
Ans: C
Feedback: 11.1
Difficulty: Easy
17. TB 11.014 What is evidence that ribosomes are nonspecific in carrying out their function?
a. Ribosomes are all exactly the same.
b. Bacterial ribosomes can be used to make proteins encoded by human mRNAs.
c. Bacterial ribosomes are smaller than eukaryotic ribosomes.
d. Bacterial ribosomes work faster than eukaryotic ribosomes.
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
WITH 100% SOLVED ANSWERS
Multiple Choice
1. TB 11.001 Who was the first to report that certain rare inherited diseases were caused by the absence
of specific enzymes?
a. Charles Darwin
b. Archibald Garrod
c. George Beadle
d. Vernon Ingram
e. James Watson
Ans: B
Feedback: 11.1
Difficulty: Easy
2. TB 11.002 Alcaptonuria is a genetic disease that is characterized by .
a. urine turning dark upon exposure to the air
b. mental retardation
c. paralysis
d. urine smelling and tasting like maple syrup
e. high fevers
Ans: A
Feedback: 11.1
Difficulty: Easy
3. TB 11.003 An alcaptonuric lacks the enzyme that oxidizes what metabolite?
a. phenylalanine
b. tyrosine
c. homogentisic acid
d. asparagine
e. pantothenic acid
Ans: C
Feedback: 11.1
Difficulty: Easy
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
,BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
4. TB 11.004 What did Archibald Garrod call diseases like alcaptonuria?
a. deadly diseases
b. inborn errors of transcription
c. homogentisms
d. errors
e. inborn errors of metabolism
Ans: E
Feedback: 11.1
Difficulty: Easy
6. TB 11.005 What did Beadle and Tatum use to generate mutations in their experimental organism? a.
mustard gas
b. irradiation
c. fluorescent dyes
d. ethidium bromide
e. Coomassie blue
Ans: B
Feedback: 11.1
Difficulty: Easy
7. TB 11.006 Beadle and Tatum's research suggested that .
a. a gene carries the information to build lipids.
b. a gene carries the information to build carbohydrates.
c. a gene carries the information for the construction of a particular enzyme
d. a gene is made of RNA
e. a gene is made of DNA
Ans: C
Feedback: 11.1
Difficulty: Medium
8. TB 11.007 Beadle and Tatum's original hypothesis had to be changed when it was discovered that some
enzymes were composed of more than one polypeptide chain?
a. the One Gene – One Enzyme hypothesis
b. the One Gene – One Polypeptide hypothesis
c. the One Polypeptide – One Enzyme hypothesis
d. the One Polypeptide – One Gene hypothesis
e. the One Gene – Two Gene
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
,BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
hypothesis Ans: B
Feedback: 11.1
Difficulty: Easy
9. TB 11.008 Why has the One Gene – One Polypeptide hypothesis had to be modified?
a. It was totally wrong.
b. Genes can be spliced differently to generate a variety of related polypeptides.
c. Enzymes sometimes consist of more than one polypeptide, each of which is coded for by its own gene.
d. Enzymes actually code for genes.
e. Polypeptides code for genes.
Ans: B
Feedback: 11.1
Difficulty: Medium
10.TB 11.009 Which scientist is best known for his work on sickle cell anemia and proving the
mechanism that causes the disease?
a. Charles Darwin
b. Archibald Garrod
c. George Beadle
d. Vernon Ingram
e. James Watson
Ans: D
Feedback: 11.1
Difficulty: Easy
11.TB 11.010 What difference between sickle cell and normal hemoglobin is apparently responsible for
all of the symptoms associated with sickle cell anemia?
a. The difference is a valine substitution in the mutant sickle cell hemoglobin for a glutamic
acid in the normal molecule.
b. The difference is a glutamic acid substitution in the mutant sickle cell hemoglobin for a
valine in the normal molecule.
c. The sickle cell hemoglobin is longer.
d. The sickle cell hemoglobin is shorter.
Ans: A
Feedback: 11.1
Difficulty: Hard
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
, BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
13. TB 11.011 What is the process by which complementary RNAs are synthesized from a DNA template?
a. translation
b. transcription
c. protein synthesis
d. transduction
e. transliteration
Ans: B
Feedback: 11.1
Difficulty: Easy
15. TB 11.012 What is the name of the process through which the code stored in mRNAs is converted
into polypeptides?
a. translation
b. transcription
c. transformation
d. transduction
e. transliteration
Ans: A
Feedback: 11.1
Difficulty: Easy
16. TB 11.013 What is the name of the molecular machine that translates the code stored in mRNAs?
a. lysosomes
b. endosomes
c. ribosomes
d. ribotomes
e. microsomes
Ans: C
Feedback: 11.1
Difficulty: Easy
17. TB 11.014 What is evidence that ribosomes are nonspecific in carrying out their function?
a. Ribosomes are all exactly the same.
b. Bacterial ribosomes can be used to make proteins encoded by human mRNAs.
c. Bacterial ribosomes are smaller than eukaryotic ribosomes.
d. Bacterial ribosomes work faster than eukaryotic ribosomes.
BIO 101 Introduction to Biology EXAM TEST QUESTIONS
WITH 100% SOLVED ANSWERS
