ATI Pharm Chapter 37: Adjuvants Medications For Pain

clic antidepressants-amitriptyline route of admin - PO/ IM onvulsants-carbamazepine route of admin - PO 3.CNS stimulants- methylphenidate route of admin - PO istamines-Hydroxyzine route of admin - PO/ IM 5.Glucocorticoids: dexamethasone route of admin - PO/ IV/IM 6. Bisphosphonates: etidronate route of admin - PO Adjuvants Medications... - used with primary pain medication, usually an opioid agonist, to increase pain relief while reducing the dosage of the opioid agonist. Adverse effects Anticonvulsants: carbamazepine, gabapentin - Bone marrow suppression Gastrointestinal distress (nausea, vomiting, and diarrhea) Adverse effects antihistamines: hydroxyzine - Sedation dry mouth Adverse effects Bisphosphonates: etidronate, pamidronate - Transient flulike symptoms Venous irritation at injection site (pamidronate) Hypocalcemia Adverse effects CNS stimulants: methylphenidate - Weight loss Insomnia Adverse effects glucocorticoids: dexamethasone - Adrenal insufficiency (hypotension, dehydration, weakness, lethargy, vomiting, diarrhea associated with prolonged use) Osteoporosis Hypokalemia Glucose intolerance Peptic ulcer disease Adverse effects Tricyclic antidepressants: amitriptyline - Orthostatic hypotension Sedation Anticholinergic effects, such as dry mouth, urinary retention, constipation, a