Chapter 18 practice questions metabolism and toxicology.

1. In which of the following locations would one NOT find spontaneous
depolarization?
- myocardium.
2. Which of the following scenarios would increase contractility of the
myocardium?
- increased activity of sacroplasmic reticulum Ca 2+ ATPase.
3. All of the following statements regarding abnormal cardiac function are true
EXCEPT:
- Right-sided heart failure results in pulmonary edema.
4. Ion balance is very important in maintaining a normal cardiac rhythm. Which of
the following statements is TRUE?
- Blockage of the Na + /K+ -ATPase increases contractility.
5. Which of the following is most likely NOT a cause of myocardial reperfusion
injury?
- inhibition of the electron transport chain.
6. Which of the following statements regarding the cardiotoxic manifestations of
ethanol consumption is FALSE?
- Acute ethanol toxicity causes an increased threshold for ventricular
fibrillation.
7. Cardiac glycosides:
- can have sympathomimetic and parasympathomimetic effects.
8. Which of the following is NOT a common cardiotoxic manifestation of cocaine
abuse?
- parasympathomimetic effects.
9. Using high doses of anabolic-androgenic steroids is NOT likely associated
with which of the following?
- increased nitric oxide synthase expression.
10. Which of the following is NOT a common mechanism of vascular toxicity?
- reduction and accumulation of LDL in endothelium.