Blood grouping ,cross matching and
blood banking
, Human blood groups
Human red blood cells contain a series of glycoproteins &
glycolipids on their surface which act as a blood group
antigens.
These antigens are unique to the individual & are
genetically controlled.
Presence or absence of these antigens is used to classify
blood groups .
On the basis of these red cell antigens, International Society
of Blood Transfusion (ISBT) Working Party recognises 30
blood group systems.
,Classification of blood group systems
MINOR systems
MAJOR SYSTEMS
• Lewis
• ABO system • MNSs
• Kell
• Rh system • Duffy
• Kidd
• Lutheran
• P1Pk
• Xg
• Diego
• Ii etc.
, ABO BLOOD GROUP SYSTEM
Most well known & clinically
important blood group system.
HISTORY :
1900- Karl Landsteiner discovered
ABO blood groups
1902- Von Decasello and Sturli,
discovered blood group AB
1911- Von Dungent and Hirzfeld –
subgroups of A- A1 & A2
blood banking
, Human blood groups
Human red blood cells contain a series of glycoproteins &
glycolipids on their surface which act as a blood group
antigens.
These antigens are unique to the individual & are
genetically controlled.
Presence or absence of these antigens is used to classify
blood groups .
On the basis of these red cell antigens, International Society
of Blood Transfusion (ISBT) Working Party recognises 30
blood group systems.
,Classification of blood group systems
MINOR systems
MAJOR SYSTEMS
• Lewis
• ABO system • MNSs
• Kell
• Rh system • Duffy
• Kidd
• Lutheran
• P1Pk
• Xg
• Diego
• Ii etc.
, ABO BLOOD GROUP SYSTEM
Most well known & clinically
important blood group system.
HISTORY :
1900- Karl Landsteiner discovered
ABO blood groups
1902- Von Decasello and Sturli,
discovered blood group AB
1911- Von Dungent and Hirzfeld –
subgroups of A- A1 & A2
