1. In a patient with metabolic alkalosis secondary to constant nasogastricsuction (and
therefore removal of gastric secretions) after abdominal surgery, which diuretic is most
likely to correct the alkalosis?
A. Furosemide.
B. Hydrochlorothiazide.
C. Acetazolamide.
D. Mannitol.
2. Hydrochlorothiazide is an important antihypertensive agent and diuretic. Choose the best
answer describing the effects of hydrochlorothiazide from the list below:
A. It can precipitate an episode of gout.
B. It can be used in the treatment of diabetes insipidis.
C. It should not be used in patients with preexisting hypercalcemia.
D. All of the above.
3. Which one of the following statements about a 42-year-old male with a history of CHF
who is being treated with spironolactone is true?
A. He has low levels of aldosterone.
B. Secretion of potassium in the cortical collecting tubules is enhanced
C. He has reduced sodium absorption in the collecting tubules.
D. He is at increased risk of hypokalemia.
4. A patient with diabetes and edema is not suggested to use the following diuretics.
A. Furosemide
B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
5. Which of the drugs listed below will enhance the ototoxicity of furosemide?
A. Gentamicin
B. Tetracycline
C. Chloramphenicol
D. Ampicillin
6. The effects of furosemide including the following EXCEPT
A. The diuretic effect is quick and strong.
B. Increase the concentration of blood uric acid
C. Effective to the pulmonary edema in patient with left heart failure
D. Inhibit Na+, K+ reabsorption in the proximal convoluted tubule
7. Which of the drugs listed below can be used in the patients with nephrolithiasis due to
idiopathic hypercalciuria?
A. Furosemide
, B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
8. Furosemide can increase the excretion of the following in urine EXCEPT
A. K+
B. Na+
C. Ca2+
D. Uric acid
9. Which of the drugs listed below can be used in the patients with Diabetes insipidus?
A. Furosemide
B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
10. Which of the diuretics listed below can NOT be used in the patients with chronic heart
failure?
A. Mannitol
B. Hydrochlorothiazide
C. Triamterene
D. Furosemide
11. Which of the following may be caused by angiotensin converting enzyme (ACE)
inhibition?
A. Angiotensinogen conversion to angiotensin I.
B. Inhibition of Angiotensin II activation of the Angiotensin II receptor
C. Enhanced conversion of Bradykinin to inactive proteins.
D. Inhibition of the conversion of Angiotensin I to Angiotensin II.
12. Activation of the Angiotensin 1 (AT-1) receptor causes which of the following?
E. Inhibition of Vasopressin (Antidiuretic hormone or ADH) release
F. Increased bradykinin
G. Aldosterone release
H. Inhibition of the conversion of Angiotensin I to Angiotensin II.
13. According to your knowledge of hypertension, which of the following statements is true?
a) Diuretics are rarely used because they are ineffective in most patients
b) Angiotensin 1 (AT-1) receptor antagonists can be used in the patients that are
not tolerance to ACE inhibitors due to the dry cough.
c) -blockers are more effective in elderly hypertension patients.
d) Achieving the blood pressure is the only goal for the pharmacologic management of
, hypertension.
14. Which of the following drugs can induce postural hypotension?
A. Captopril
B. Hydrocholorothiazide
C. Losartan
D. Prazosin
15. The pharmacological mechanism under the long term therapeutic effect of diuretics on
hypertension is,
A. Antagonize calcium
B. Reduce the blood volume
C. Decrease the sodium in vascular smooth muscle
D. Inhibit Renin release
16. Nifedipine can induce the following response during the treatment of hypertension,
A. Decrease the glucose tolerence
B. Increase the heart rate
C. Decrease the cardiac output
D. Increase renin release
17. The mechanism under the therapeutic effect of -blockers on hypertension induces
A. reduce cardiac output
B. Increase rennin release
C. Dilate the peripheral vessels
D. Decrease the blood volume
18. Which of the following is most commonly used during the hypertension emergency?
A. Furosemide
B. Captopril
C. Hydrochlorothiazide
D. propralonol
19. A 53 yr boat captain with a history of hypertension was apparently unconscious when the
Staten Island ferry he was piloting crashed. The patient was taking hydrochlorothiazide,
lisinopril and metoprolol for blood pressure control. Which of the following may have
contributed to his loss of consciousness?
A. Volume depletion, and reduce conversion of angiotensinogen to angiotensin I by
metoprolol.
B. Volume depletion, and reduced conversion of angiotensinogen to angiotensin I by
lisinopril.
C. Volume depletion, and increased stimulation of beta-1 receptors by metoprolol.
D. Volume depletion, and reduced stimulation of beta-1 receptors by metoprolol.
therefore removal of gastric secretions) after abdominal surgery, which diuretic is most
likely to correct the alkalosis?
A. Furosemide.
B. Hydrochlorothiazide.
C. Acetazolamide.
D. Mannitol.
2. Hydrochlorothiazide is an important antihypertensive agent and diuretic. Choose the best
answer describing the effects of hydrochlorothiazide from the list below:
A. It can precipitate an episode of gout.
B. It can be used in the treatment of diabetes insipidis.
C. It should not be used in patients with preexisting hypercalcemia.
D. All of the above.
3. Which one of the following statements about a 42-year-old male with a history of CHF
who is being treated with spironolactone is true?
A. He has low levels of aldosterone.
B. Secretion of potassium in the cortical collecting tubules is enhanced
C. He has reduced sodium absorption in the collecting tubules.
D. He is at increased risk of hypokalemia.
4. A patient with diabetes and edema is not suggested to use the following diuretics.
A. Furosemide
B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
5. Which of the drugs listed below will enhance the ototoxicity of furosemide?
A. Gentamicin
B. Tetracycline
C. Chloramphenicol
D. Ampicillin
6. The effects of furosemide including the following EXCEPT
A. The diuretic effect is quick and strong.
B. Increase the concentration of blood uric acid
C. Effective to the pulmonary edema in patient with left heart failure
D. Inhibit Na+, K+ reabsorption in the proximal convoluted tubule
7. Which of the drugs listed below can be used in the patients with nephrolithiasis due to
idiopathic hypercalciuria?
A. Furosemide
, B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
8. Furosemide can increase the excretion of the following in urine EXCEPT
A. K+
B. Na+
C. Ca2+
D. Uric acid
9. Which of the drugs listed below can be used in the patients with Diabetes insipidus?
A. Furosemide
B. Hydrochlorothiazide
C. Triamterene
D. Spironolactone
10. Which of the diuretics listed below can NOT be used in the patients with chronic heart
failure?
A. Mannitol
B. Hydrochlorothiazide
C. Triamterene
D. Furosemide
11. Which of the following may be caused by angiotensin converting enzyme (ACE)
inhibition?
A. Angiotensinogen conversion to angiotensin I.
B. Inhibition of Angiotensin II activation of the Angiotensin II receptor
C. Enhanced conversion of Bradykinin to inactive proteins.
D. Inhibition of the conversion of Angiotensin I to Angiotensin II.
12. Activation of the Angiotensin 1 (AT-1) receptor causes which of the following?
E. Inhibition of Vasopressin (Antidiuretic hormone or ADH) release
F. Increased bradykinin
G. Aldosterone release
H. Inhibition of the conversion of Angiotensin I to Angiotensin II.
13. According to your knowledge of hypertension, which of the following statements is true?
a) Diuretics are rarely used because they are ineffective in most patients
b) Angiotensin 1 (AT-1) receptor antagonists can be used in the patients that are
not tolerance to ACE inhibitors due to the dry cough.
c) -blockers are more effective in elderly hypertension patients.
d) Achieving the blood pressure is the only goal for the pharmacologic management of
, hypertension.
14. Which of the following drugs can induce postural hypotension?
A. Captopril
B. Hydrocholorothiazide
C. Losartan
D. Prazosin
15. The pharmacological mechanism under the long term therapeutic effect of diuretics on
hypertension is,
A. Antagonize calcium
B. Reduce the blood volume
C. Decrease the sodium in vascular smooth muscle
D. Inhibit Renin release
16. Nifedipine can induce the following response during the treatment of hypertension,
A. Decrease the glucose tolerence
B. Increase the heart rate
C. Decrease the cardiac output
D. Increase renin release
17. The mechanism under the therapeutic effect of -blockers on hypertension induces
A. reduce cardiac output
B. Increase rennin release
C. Dilate the peripheral vessels
D. Decrease the blood volume
18. Which of the following is most commonly used during the hypertension emergency?
A. Furosemide
B. Captopril
C. Hydrochlorothiazide
D. propralonol
19. A 53 yr boat captain with a history of hypertension was apparently unconscious when the
Staten Island ferry he was piloting crashed. The patient was taking hydrochlorothiazide,
lisinopril and metoprolol for blood pressure control. Which of the following may have
contributed to his loss of consciousness?
A. Volume depletion, and reduce conversion of angiotensinogen to angiotensin I by
metoprolol.
B. Volume depletion, and reduced conversion of angiotensinogen to angiotensin I by
lisinopril.
C. Volume depletion, and increased stimulation of beta-1 receptors by metoprolol.
D. Volume depletion, and reduced stimulation of beta-1 receptors by metoprolol.
