Lehninger Principles of Biochemistry: Chapter 6 Key Terms

activation energy (ΔG‡) - The amount of energy (in joules) required to convert all the molecules in 1 mol of a reacting substance from the ground state to the transition state. active site - The region of an enzyme surface that binds the substrate molecule and catalytically transforms it; also known as the catalytic site. allosteric enzyme - A regulatory enzyme with catalytic activity modulated by the noncovalent binding of a specific metabolite at a site other than the active site. allosteric modulator (allosteric effector) - A substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein. apoenzyme - The protein portion of an enzyme, exclusive of any organic or inorganic cofactors or prosthetic groups that might be required for catalytic activity. apoprotein - The protein portion of a protein, exclusive of any organic or inorganic cofactors or prosthetic groups that might be required for activity. binding energy (ΔGᵦ) - The energy derived from noncovalent interactions between enzyme and substrate or receptor and ligand.