CLASSIFICATION OF THE DRUGS
DRUGS FROM
DRUGS AFFECTING THE ORGANS CHEMOTHERAPEUTIC DIFFERENT
DRUGS AFFECTING THE NERVOUS SYSTEM
AND TISSUES DRUGS PHARMACOLOGICAL
GROUPS
Drugs affecting peripheral Antitumor drugs
Drugs affecting the cardiovascular Antimicrobial, antiviral,
Drugs affecting the nervous system Antiallergic drugs
system antiparasitic drugs
central nervous system Drugs affecting the sensory Antidotes
nerve endings Cardiac glycosides Antibiotics
CNS DEPRESSANTS (AFFECTING THE Antihypertensive drugs Sulfonamides
Analgesics (opioid, AFFERENT INNERVATION) Antianginal drugs Antituberculous drugs
analgesics-antipyretics, Antiarrhythmic drugs Antihelminthic drugs
NSAIDs) Local anaesthetics Antihyperlipidemic drugs Antifungal drugs
Sedative and hypnotic Coating drugs Spasmolytics Antiviral drugs
drugs Adsorbents Drugs affecting the excretory system Antimalarial drugs
Tranquilizers Astringents Diuretics Antisyphilitic drugs
Neuroleptics Expectorants Drugs affecting the hemopoietic system Antiseptics
Anticonvulsants Irritant drugs Drugs affecting blood coagulation Disinfectants
Antiparkinsonian drugs Drugs affecting peripheral Drugs affecting erythro- and leukopoiesis
General anaesthetics neurotransmitter processes Drugs affecting the digestive system
CNS STIMULANTS (AFFECTING THE Anorectic drugs
Psychomotor stimulants EFFERENT PART OF THE Bitter stuffs. Drugs for replacement therapy
Analeptics NERVOUS SYSTEM) Antiacid drugs
Antidepressants Direct-acting-cholinomimetics Antiulcer drugs
Nootropics (Cognitive Anticholinesterase drugs Hepatoprotectors
enhancers) M- cholinoblockers Laxative drugs. Drugs against diarrhea
Adaptogens Ganglionic blockers Drugs affecting metabolism
Drugs affecting the Muscle relaxants Hormonal drugs of hypophysis, thyroid,
cerebral blood circulation Adrenomimetics parathyroid, gonads, adrenal gland cortex,
Adrenoblockers anabolic steroids
Sympatholytics Insulins and oral hypoglycemic drugs
Vitamins, macro- and microelements
Enzymes. Antienzymes
Drugs for transfusion therapy
, NARCOTIC (OPIOID) ANALGESICS
CLASSIFICATION NATURAL AND SEMI-SYNTHETIC SYNTHETIC AGENTS
AGENTS
1. Morphine 5. Trimeperidine (Promedol) 10. Dimenoxadol h/chl. (Estocin)
2. Codeine 6. Fentanyl 11. Pentazocine (Fortral)
3. Aethylmorphine h/chl. (Dionine) 7. Piritramide (Dipidolor) 12. Butorphanol (Moradol)
Drugs and their synonyms 4. Omnopon 8. Tilidine (Valoron) 13. Buprenorphine (Norphine)
9. Sufentanil 14. Tramadol
Binding to opioid receptors in the CNS → inhibition of the algogens release on the whole way of pain impulses passing.
Mechanism of action Inhibition of the intercalary neurons of the spinal cord, reticular formation, thalamic pain centers, summation ability of the CNS.
Inhibition of the pain, cough, emetic and respiratory centers.
Pharmacological effects Stimulation of vagus nerve and oculomotor nerve (miosis) centers.
Indications and Strong and very strong pains (1,3-14), neuroleptanalgesia (6), premedication and post-operation period (1,4-14), labour analgesia (5,7,9,10),
interchangeability colics (5-6,8-10,12), eye diseases (3), strong persistent cough (2,3,10).
Narcotic analgesics are incompatible with antiparkinsonian agents, MAO inhibitors, peripheral acting muscle relaxants, -adrenoblockers,
glucocorticoids, ACTH.
Morphine is incompatible with aminazine in the same syringe.
Promedol is incompatible with antihistaminic agents, tubocurarin chloride, trasicor.
Pentazocine must not be injected with barbiturates in the same syringe.
Doctor and pharmacist, Codeine phosphate shouldn’t be taken together with methotrexate.
remember! Tramadol for injections is incompatible with solutions of diazepam, flunitrazepam, nitroglycerin, phenylbutazone.
Narcotic analgesics aren’t prescribed for children up to 2 years and butorphanol - up to 18 years old.
All drugs containing natural opium alkaloids, inhibit the peristalsis and secretion of GIT.
Codeine as a part of the complex drugs causes euphoria and addiction very rarely.
Specific antagonist of the narcotic analgesics is naloxone.
Before meals: 11.
, ANALGESICS-ANTIPYRETICS
CLASSIFICATION PYRAZOLONE DERIVATIVES PARAAMINOPHENOL COMBINED AGENTS
DERIVATIVES
1. Methamizole sodium (Analgin) 2. Paracetamol (Panadol) 3.Sedalgin 7. Citropac
4. Tempalgin 8. Cyclopar
5. Baralgin 9. Ascopar
Drugs and their synonyms 6. Citramon 10. Paravit
Decrease of the pain impulses transmission through afferent nerves and inhibition of subcortical pain centers. Thermoregulation center
Mechanism of action suppression.
Analgesic (1-10), antipyretic (1-3,6-10), anti-inflammatory (6-7,9), sedative (3,4), spasmolytic (5,8).
Pharmacological effects Side effects: allergy, suppression of hemopoiesis (1-10), nephritis (2,3,4); nausea, vomiting, methemoglobin formation, stomach ulceration (1,3-
5), decrease of blood coagulation (1,3,7).
Indications and
Pains, not dangerous for life (headache, toothache, articular pain, etc.) (1-10), fever (2,6-7,9,10), neuralgia (1-4); colics, spasms of coronary and
interchangeability cerebral vessels (5-8).
Analgesics-antipyretics are incompatible with sulfonamides, antidepressants, glucocorticoids, anticoagulants.
Doctor and pharmacist,
Analgesics, especially pyrazolone derivatives, are incompatible with salicylates, dichlothiazide.
remember! The long-term administration of anticonvulsants may decrease the paracetamol activity.
, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)
PYRAZOLONE AND COMBINED AGENTS
SALICYLIC ACID ARYLCARBONIC OXICAMS AND
CLASSIFICATION INDOLEACETIC AND OTHER
DERIVATIVES ACID DERIVATIVES FENAMATES
ACID DERIVATIVES NSAIDs*
1. Acetylsalicylic acid 3. Ketoprofen (Ketonal) 6.Meloxicam 10.Phenylbutazone 13.Reopyrin
(Aspirin) 4.Sodium diclofenac (Movalise) (Butadion) 14.Novigan
2.Lysin acetylsalicylate (Voltaren, Orthofen) 7.Piroxicam 11.Clofezone 15.Arthrotek
(Aspisol) 5.Thiaprofenic acid 8.Niflumic acid 12.Indomethacin 16.Fortalgin C
(Surgam) (Donalgin) (Methindole) 17.Etodolac* (Elderin)
Drugs and their synonyms 9. Mefenamic acid 18. Ketorolac*
19. Diclocaine
20.Ascofen
21.Inflagesic plus
22.Valcofen
Suppression of the cyclooxygenase activity (COX), disturbance of the prostaglandins and thromboxane synthesis, suppression of the
Mechanism of action inflammatory mediators, hyaluronidase, lysosomal hydrolases activity. Decrease of the energy supply in the inflammatory focus. Inhibition of the
subcortical pain centers.
Anti-inflammatory, antipyretic, analgesic, antiaggregant (1-22); sedative, anticonvulsive (22).
Pharmacological effects Side effects: gastric ulceration, allergic reactions, bleedings, leukopenia, bronchospasm (seldom).
Diseases of the connective tissue (1-13,15,17,19); myalgia, arthralgia, bursitis (1-13,15-18,20-21); headache (1,2,9,14,16,20-22), hyperthermia
Indications and (1,2,9,16,20-22); acute respiratory viral diseases (1,9,16,20-22), tendency of convulsive states appearance at high temperature in children (22),
interchangeability pains in the traumatic injuries (1-5,7-10,12-18,21), arthritis (3-13,15,17,19,21), gout (10-13), glomerulonephritis (12), thrombophlebitis (1,2,10-
12), thromboprophylaxis, hypercoagulant syndrome (1,2); renal, hepatic and intestinal colics (14), postoperative pain syndrome (5,17,18,21).
Salicylates mustn’t be combined with other NSAIDs (the ulcerogenic effect increases) and anticoagulants (the risk of bleeding increases).
Butadion is incompatible with glucocorticoids.
Doctor and pharmacist,
Indomethacin decreases the effects of -adrenoblockers and saluretics.
remember! Meloxicam is incompatible with cyclosporin, methotrexate, diuretics.
After meals: 1,3-5,8-10,15,17.
HYPNOTIC AND SEDATIVE DRUGS
DRUGS FROM
DRUGS AFFECTING THE ORGANS CHEMOTHERAPEUTIC DIFFERENT
DRUGS AFFECTING THE NERVOUS SYSTEM
AND TISSUES DRUGS PHARMACOLOGICAL
GROUPS
Drugs affecting peripheral Antitumor drugs
Drugs affecting the cardiovascular Antimicrobial, antiviral,
Drugs affecting the nervous system Antiallergic drugs
system antiparasitic drugs
central nervous system Drugs affecting the sensory Antidotes
nerve endings Cardiac glycosides Antibiotics
CNS DEPRESSANTS (AFFECTING THE Antihypertensive drugs Sulfonamides
Analgesics (opioid, AFFERENT INNERVATION) Antianginal drugs Antituberculous drugs
analgesics-antipyretics, Antiarrhythmic drugs Antihelminthic drugs
NSAIDs) Local anaesthetics Antihyperlipidemic drugs Antifungal drugs
Sedative and hypnotic Coating drugs Spasmolytics Antiviral drugs
drugs Adsorbents Drugs affecting the excretory system Antimalarial drugs
Tranquilizers Astringents Diuretics Antisyphilitic drugs
Neuroleptics Expectorants Drugs affecting the hemopoietic system Antiseptics
Anticonvulsants Irritant drugs Drugs affecting blood coagulation Disinfectants
Antiparkinsonian drugs Drugs affecting peripheral Drugs affecting erythro- and leukopoiesis
General anaesthetics neurotransmitter processes Drugs affecting the digestive system
CNS STIMULANTS (AFFECTING THE Anorectic drugs
Psychomotor stimulants EFFERENT PART OF THE Bitter stuffs. Drugs for replacement therapy
Analeptics NERVOUS SYSTEM) Antiacid drugs
Antidepressants Direct-acting-cholinomimetics Antiulcer drugs
Nootropics (Cognitive Anticholinesterase drugs Hepatoprotectors
enhancers) M- cholinoblockers Laxative drugs. Drugs against diarrhea
Adaptogens Ganglionic blockers Drugs affecting metabolism
Drugs affecting the Muscle relaxants Hormonal drugs of hypophysis, thyroid,
cerebral blood circulation Adrenomimetics parathyroid, gonads, adrenal gland cortex,
Adrenoblockers anabolic steroids
Sympatholytics Insulins and oral hypoglycemic drugs
Vitamins, macro- and microelements
Enzymes. Antienzymes
Drugs for transfusion therapy
, NARCOTIC (OPIOID) ANALGESICS
CLASSIFICATION NATURAL AND SEMI-SYNTHETIC SYNTHETIC AGENTS
AGENTS
1. Morphine 5. Trimeperidine (Promedol) 10. Dimenoxadol h/chl. (Estocin)
2. Codeine 6. Fentanyl 11. Pentazocine (Fortral)
3. Aethylmorphine h/chl. (Dionine) 7. Piritramide (Dipidolor) 12. Butorphanol (Moradol)
Drugs and their synonyms 4. Omnopon 8. Tilidine (Valoron) 13. Buprenorphine (Norphine)
9. Sufentanil 14. Tramadol
Binding to opioid receptors in the CNS → inhibition of the algogens release on the whole way of pain impulses passing.
Mechanism of action Inhibition of the intercalary neurons of the spinal cord, reticular formation, thalamic pain centers, summation ability of the CNS.
Inhibition of the pain, cough, emetic and respiratory centers.
Pharmacological effects Stimulation of vagus nerve and oculomotor nerve (miosis) centers.
Indications and Strong and very strong pains (1,3-14), neuroleptanalgesia (6), premedication and post-operation period (1,4-14), labour analgesia (5,7,9,10),
interchangeability colics (5-6,8-10,12), eye diseases (3), strong persistent cough (2,3,10).
Narcotic analgesics are incompatible with antiparkinsonian agents, MAO inhibitors, peripheral acting muscle relaxants, -adrenoblockers,
glucocorticoids, ACTH.
Morphine is incompatible with aminazine in the same syringe.
Promedol is incompatible with antihistaminic agents, tubocurarin chloride, trasicor.
Pentazocine must not be injected with barbiturates in the same syringe.
Doctor and pharmacist, Codeine phosphate shouldn’t be taken together with methotrexate.
remember! Tramadol for injections is incompatible with solutions of diazepam, flunitrazepam, nitroglycerin, phenylbutazone.
Narcotic analgesics aren’t prescribed for children up to 2 years and butorphanol - up to 18 years old.
All drugs containing natural opium alkaloids, inhibit the peristalsis and secretion of GIT.
Codeine as a part of the complex drugs causes euphoria and addiction very rarely.
Specific antagonist of the narcotic analgesics is naloxone.
Before meals: 11.
, ANALGESICS-ANTIPYRETICS
CLASSIFICATION PYRAZOLONE DERIVATIVES PARAAMINOPHENOL COMBINED AGENTS
DERIVATIVES
1. Methamizole sodium (Analgin) 2. Paracetamol (Panadol) 3.Sedalgin 7. Citropac
4. Tempalgin 8. Cyclopar
5. Baralgin 9. Ascopar
Drugs and their synonyms 6. Citramon 10. Paravit
Decrease of the pain impulses transmission through afferent nerves and inhibition of subcortical pain centers. Thermoregulation center
Mechanism of action suppression.
Analgesic (1-10), antipyretic (1-3,6-10), anti-inflammatory (6-7,9), sedative (3,4), spasmolytic (5,8).
Pharmacological effects Side effects: allergy, suppression of hemopoiesis (1-10), nephritis (2,3,4); nausea, vomiting, methemoglobin formation, stomach ulceration (1,3-
5), decrease of blood coagulation (1,3,7).
Indications and
Pains, not dangerous for life (headache, toothache, articular pain, etc.) (1-10), fever (2,6-7,9,10), neuralgia (1-4); colics, spasms of coronary and
interchangeability cerebral vessels (5-8).
Analgesics-antipyretics are incompatible with sulfonamides, antidepressants, glucocorticoids, anticoagulants.
Doctor and pharmacist,
Analgesics, especially pyrazolone derivatives, are incompatible with salicylates, dichlothiazide.
remember! The long-term administration of anticonvulsants may decrease the paracetamol activity.
, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)
PYRAZOLONE AND COMBINED AGENTS
SALICYLIC ACID ARYLCARBONIC OXICAMS AND
CLASSIFICATION INDOLEACETIC AND OTHER
DERIVATIVES ACID DERIVATIVES FENAMATES
ACID DERIVATIVES NSAIDs*
1. Acetylsalicylic acid 3. Ketoprofen (Ketonal) 6.Meloxicam 10.Phenylbutazone 13.Reopyrin
(Aspirin) 4.Sodium diclofenac (Movalise) (Butadion) 14.Novigan
2.Lysin acetylsalicylate (Voltaren, Orthofen) 7.Piroxicam 11.Clofezone 15.Arthrotek
(Aspisol) 5.Thiaprofenic acid 8.Niflumic acid 12.Indomethacin 16.Fortalgin C
(Surgam) (Donalgin) (Methindole) 17.Etodolac* (Elderin)
Drugs and their synonyms 9. Mefenamic acid 18. Ketorolac*
19. Diclocaine
20.Ascofen
21.Inflagesic plus
22.Valcofen
Suppression of the cyclooxygenase activity (COX), disturbance of the prostaglandins and thromboxane synthesis, suppression of the
Mechanism of action inflammatory mediators, hyaluronidase, lysosomal hydrolases activity. Decrease of the energy supply in the inflammatory focus. Inhibition of the
subcortical pain centers.
Anti-inflammatory, antipyretic, analgesic, antiaggregant (1-22); sedative, anticonvulsive (22).
Pharmacological effects Side effects: gastric ulceration, allergic reactions, bleedings, leukopenia, bronchospasm (seldom).
Diseases of the connective tissue (1-13,15,17,19); myalgia, arthralgia, bursitis (1-13,15-18,20-21); headache (1,2,9,14,16,20-22), hyperthermia
Indications and (1,2,9,16,20-22); acute respiratory viral diseases (1,9,16,20-22), tendency of convulsive states appearance at high temperature in children (22),
interchangeability pains in the traumatic injuries (1-5,7-10,12-18,21), arthritis (3-13,15,17,19,21), gout (10-13), glomerulonephritis (12), thrombophlebitis (1,2,10-
12), thromboprophylaxis, hypercoagulant syndrome (1,2); renal, hepatic and intestinal colics (14), postoperative pain syndrome (5,17,18,21).
Salicylates mustn’t be combined with other NSAIDs (the ulcerogenic effect increases) and anticoagulants (the risk of bleeding increases).
Butadion is incompatible with glucocorticoids.
Doctor and pharmacist,
Indomethacin decreases the effects of -adrenoblockers and saluretics.
remember! Meloxicam is incompatible with cyclosporin, methotrexate, diuretics.
After meals: 1,3-5,8-10,15,17.
HYPNOTIC AND SEDATIVE DRUGS
