Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition By Michelle J.
Willihnganz, Samuel L. Gurevitz, Bruce Clayton Chapter 1-48
Table Of Content
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1. Drug Definitions, Standards, and Information Sources
Chapter 2. Basic Principles of Drug Action and Drug Interactions
Chapter 3. Drug Action Across the Life Span
Chapter 4. The Nursing Process and Pharmacology
Chapter 5. Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration
Chapter 6. Principles of Medication Administration and Medication Safety
Chapter 7. Percutaneous Administration
Chapter 8. Enteral Administration
Chapter 9. Parenteral Administration: Safe Preparation of Parenteral Medications
Chapter 10. Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
Routes Chapter 11. Parenteral Administration: Intravenous Route
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems
Chapter 12. Drugs Affecting the Autonomic Nervous System
Chapter 13. Drugs Used for Sleep
Chapter 14. Drugs Used for Neurodegenerative Disorders NEW!)
Chapter 15. Drugs Used for Anxiety Disorders
Chapter 16. Drugs Used for Depressive and Bipolar Disorders
Chapter 17. Drugs Used for Psychoses
Chapter 18. Drugs Used for Seizure Disorders
Chapter 19. Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System
Chapter 20. Introduction to Cardiovascular Disease and Metabolic Syndrome
Chapter 21. Drugs Used to Treat Dyslipidemias
Chapter 22. Drugs Used to Treat Hypertension
Chapter 23. Drugs Used to Treat Dysrhythmias
Chapter 24. Drugs Used to Treat Angina Pectoris
Chapter 25. Drugs Used to Treat Peripheral Vascular Disease
Chapter 26. Drugs Used to Treat Thromboembolic Disorders
Chapter 27. Drugs Used to Treat Heart Failure
Chapter 28. Drugs Used for Diuresis
Unit 5: Drugs Affecting the Respiratory System
Chapter 29. Drugs Used to Treat Upper Respiratory Disease
Chapter 30. Drugs Used to Treat Lower Respiratory Disease
Unit 6: Drugs Affecting the Digestive System
Chapter 31. Drugs Used to Treat Oral Disorders
Chapter 32. Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
Chapter 33. Drugs Used to Treat Nausea and Vomiting
Chapter 34. Drugs Used to Treat Constipation and Diarrhea
Unit 7: Drugs That Affect the Endocrine System
Chapter 35. Drugs Used to Treat Diabetes Mellitus
Chapter 36. Drugs Used to Treat Thyroid Disease
Chapter 37. Corticosteroids
Chapter 38. Gonadal Hormones
Chapter Unit 8: Drugs Affecting the Reproductive System
Chapter 39. Drugs Used in Obstetrics
Chapter 40. Drugs Used in Men‘s and Women‘s Health
Chapter 41. Drugs Used to Treat Disorders of the Urinary System
Chapter 42. Drugs Used to Treat Glaucoma and Other Eye Disorders
Chapter43. Drugs Used to Treat Cancer
Chapter44. Drugs Used to Treat Musculoskeletal Disorders
Chapter 45. Drugs Used to Treat Infections
,Chapter 46. Nutrition
Chapter 47. Herbal and Dietary Supplement Therapy
Chapter 48. Substance Abuse
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by the FDA. The brand name, or
trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
name is provided by the United States Adopted Names Council.
DIF: Cognitive Level: Knowledge REF: p. 9 OBJ: 1
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
names, pronunciation guide, and possible future FDA approved drugs; it does not include
nutritional supplements. Natural Medicines Comprehensive Database contains
evidence-based information on herbal medicines and herbal combination products; it does not
include information specific to nutritional supplements. Drug Interaction Facts contains
comprehensive information on drug interaction facts; it does not include nutritional
supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
therapeutic class. Monographs are formatted as tables to allow comparison of similar
products, brand names, manufacturers, cost indices, and available dosage forms
Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
, OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug available
in the United States and describes therapeutic uses of drugs, including approved and
unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including approved and
unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public a
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
up-to-date look up and downloadable resource about medicines. The American Drug Index is
not appropriate for patient use. The American Hospital Formulary is not appropriate for
patient use. The drug reference is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
cannot be used safely without medical supervision and restricts their sale to prescription by a
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
, 7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
drugs have low potential for abuse. Use may lead to limited physical or psychological
dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an outbreak
of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
become a priority concern in the world. Orphan diseases are not researched in a priority
manner. Preclinical research is not omitted. Extending any phase of the research would mean
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
clinical research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
9. Which statement is true about over-the-counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a healthcare provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and trade,
can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription
drugs require an order by a health professional who is licensed to prescribe, such as a
physician, nurse practitioner, physician assistant, or dentist.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Patient Education
10. Which is the most authoritative reference for medications that are injected?
a. Martindale: The Complete
b. Handbook on Injectable Drugs
c. DailyMed
Willihnganz, Samuel L. Gurevitz, Bruce Clayton Chapter 1-48
Table Of Content
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1. Drug Definitions, Standards, and Information Sources
Chapter 2. Basic Principles of Drug Action and Drug Interactions
Chapter 3. Drug Action Across the Life Span
Chapter 4. The Nursing Process and Pharmacology
Chapter 5. Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration
Chapter 6. Principles of Medication Administration and Medication Safety
Chapter 7. Percutaneous Administration
Chapter 8. Enteral Administration
Chapter 9. Parenteral Administration: Safe Preparation of Parenteral Medications
Chapter 10. Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
Routes Chapter 11. Parenteral Administration: Intravenous Route
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems
Chapter 12. Drugs Affecting the Autonomic Nervous System
Chapter 13. Drugs Used for Sleep
Chapter 14. Drugs Used for Neurodegenerative Disorders NEW!)
Chapter 15. Drugs Used for Anxiety Disorders
Chapter 16. Drugs Used for Depressive and Bipolar Disorders
Chapter 17. Drugs Used for Psychoses
Chapter 18. Drugs Used for Seizure Disorders
Chapter 19. Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System
Chapter 20. Introduction to Cardiovascular Disease and Metabolic Syndrome
Chapter 21. Drugs Used to Treat Dyslipidemias
Chapter 22. Drugs Used to Treat Hypertension
Chapter 23. Drugs Used to Treat Dysrhythmias
Chapter 24. Drugs Used to Treat Angina Pectoris
Chapter 25. Drugs Used to Treat Peripheral Vascular Disease
Chapter 26. Drugs Used to Treat Thromboembolic Disorders
Chapter 27. Drugs Used to Treat Heart Failure
Chapter 28. Drugs Used for Diuresis
Unit 5: Drugs Affecting the Respiratory System
Chapter 29. Drugs Used to Treat Upper Respiratory Disease
Chapter 30. Drugs Used to Treat Lower Respiratory Disease
Unit 6: Drugs Affecting the Digestive System
Chapter 31. Drugs Used to Treat Oral Disorders
Chapter 32. Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
Chapter 33. Drugs Used to Treat Nausea and Vomiting
Chapter 34. Drugs Used to Treat Constipation and Diarrhea
Unit 7: Drugs That Affect the Endocrine System
Chapter 35. Drugs Used to Treat Diabetes Mellitus
Chapter 36. Drugs Used to Treat Thyroid Disease
Chapter 37. Corticosteroids
Chapter 38. Gonadal Hormones
Chapter Unit 8: Drugs Affecting the Reproductive System
Chapter 39. Drugs Used in Obstetrics
Chapter 40. Drugs Used in Men‘s and Women‘s Health
Chapter 41. Drugs Used to Treat Disorders of the Urinary System
Chapter 42. Drugs Used to Treat Glaucoma and Other Eye Disorders
Chapter43. Drugs Used to Treat Cancer
Chapter44. Drugs Used to Treat Musculoskeletal Disorders
Chapter 45. Drugs Used to Treat Infections
,Chapter 46. Nutrition
Chapter 47. Herbal and Dietary Supplement Therapy
Chapter 48. Substance Abuse
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by the FDA. The brand name, or
trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
name is provided by the United States Adopted Names Council.
DIF: Cognitive Level: Knowledge REF: p. 9 OBJ: 1
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
names, pronunciation guide, and possible future FDA approved drugs; it does not include
nutritional supplements. Natural Medicines Comprehensive Database contains
evidence-based information on herbal medicines and herbal combination products; it does not
include information specific to nutritional supplements. Drug Interaction Facts contains
comprehensive information on drug interaction facts; it does not include nutritional
supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
therapeutic class. Monographs are formatted as tables to allow comparison of similar
products, brand names, manufacturers, cost indices, and available dosage forms
Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
, OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug available
in the United States and describes therapeutic uses of drugs, including approved and
unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including approved and
unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public a
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
up-to-date look up and downloadable resource about medicines. The American Drug Index is
not appropriate for patient use. The American Hospital Formulary is not appropriate for
patient use. The drug reference is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
cannot be used safely without medical supervision and restricts their sale to prescription by a
licensed practitioner. The Controlled Substances Act addresses only controlled substances and
their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
, 7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
drugs have low potential for abuse. Use may lead to limited physical or psychological
dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an outbreak
of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
become a priority concern in the world. Orphan diseases are not researched in a priority
manner. Preclinical research is not omitted. Extending any phase of the research would mean
a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
clinical research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
9. Which statement is true about over-the-counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a healthcare provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and trade,
can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription
drugs require an order by a health professional who is licensed to prescribe, such as a
physician, nurse practitioner, physician assistant, or dentist.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Patient Education
10. Which is the most authoritative reference for medications that are injected?
a. Martindale: The Complete
b. Handbook on Injectable Drugs
c. DailyMed
