BIOPHARMACEUTICS ALL POSSIBLE QUESTIONS AND ANSWERS 2023 GRADED A

BIOPHARMACEUTICS ALL POSSIBLE QUESTIONS AND ANSWERS 2023 GRADED A In LADMER system, L stands for liberation as the first step which determines the following aspects, except: a. onset of action c. rate of absorption b. type of preparation d. bioavailability b. type of preparation The ultimate evaluation of dosage forms or delivery system is in: a. disintegration time c. clinical effectiveness b. thickness d. taste c. clinical effectiveness Factor that contributes to patient's difference in drug concentration in the body, except: a. body weight c. age b. obesity d. climate d. climate A rate limiting factor in the dissolution of drugs is: a. disintegration of the tablet b. thickness c. content uniformity d. local effect a. disintegration of the tablet The effect of reduced particle size of a drug is: a. increased absorption c. increased hardness b. increased disintegration d. all of them a. increased absorption A cause of patient to patient variability of time course of the drug in the plasma is: a. disease c. genetic in origin b. concomitant drug therapy d. all of the above d. all of the above Dissolution rate tests can be used to predict bioavailability if: a. dissolved drug remains free in the GIT b. dissolved drug is decomposed in the GIT c. drug is hydrolyzed in the GIT d. all of them a. dissolved drug remains free in the GIT Elimination half-life of a drug is the time in hours needed to reduce drug concentration to: a. half of the parent drug c. all or taken dose b. one fourth of the initial dose d. a & b a. half of the parent drug Tmax means: a. time of great solubility of the drug c. time of peak concentration b. peak height concentration d. AUC values c. time of peak concentration