TOXICOLOGY (GREEN PACOP) 2023 QUESTIONS
AND ANSWERS WITH COMPLETE SOLUTION
This is obtained from an examination of the tissues and organs of the dead.
a. Experimental evidence c. post-mortem evidence
b. Chemical evidence d. circumstantial evidence
c. post-mortem evidence
Death may result from poisoning due to the following causes, except: a. due to
interference with the carriage of oxygen
b. due to inhibition of the respiratory movements by neuro muscular agents
c. due to interference with the enzyme system utilizing it
d. circulatory failure as a result of cardiac glucosides
c. due to interference with the enzyme system utilizing it
The most serious potential consequence of ingestion of liquid hydrocarbon such as
kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. the aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison
b. the aspiration of the poison into the respiratory tract
The specific antidote for the treatment of poisoning due to oral ingestion of silver nitrate
would be the oral administration of :
a. acetic acid solution
b. normal saline
c. sodium bicarbonate
b. normal saline
Catharsis as a way of removing a poison include the ff. except:
a. increases intestinal injury when a corrosive is ingested
b. is avoided in a patient showing disturbed electrolyte imbalance
c. hypertonic cathartic and enemas are hazardous in the presence of impaired renal
function
d. none of the above
d. none of the above
This is recommended in phenol poisoning as a cathartic but is contraindicated in
poisoning by chlorinated insecticide, since it may increase intestinal absorption
a. magnesium sulfate c. mannitol
b. castor oil d. Fleet's Phospho-soda
b. castor oil
A poison which increases suddenly in its intensity of action after slow or gradual
addition of it is
a. corrosive poison c. true poison
b. cumulative poison d. irritant poison
b. cumulative poison
,Streptomycin can cause:
a. 4th cranial damage c. 8th cranial damage
b. 7th cranial damage d. 6th cranial damage
c. 8th cranial damage
Most accidental poisoning in children is caused by:
a. detergents
b. bleaches
c. crayons
d. insecticides
e. salicylate analgesics
c. crayons
Antidote for iodine poisoning:
a. silver nitrate c. potassium nitrate
b. starch d. sugar
b. starch
The evidences to be saved in nonfatal poisoning are the following, except:
a. lung d. blood
b. urine e. body fat
c. food
a. lung
A specialized field of toxicology that designates an area of professional emphasis within
the realm of medical science.
a. Forensic toxicology c. Environmental toxicology
b. Clinical toxicology d. Regulatory toxicology
b. Clinical toxicology
This is an area of toxicology which is concerned directly with toxicity testing, which
provides necessary information for safety evaluation and regulatory requirements.
a. mechanistic toxicology c. descriptive toxicology
b. regulatory toxicology d. forensic toxicology
c. descriptive toxicology
The quantity of medicine that can kill an organism
a. fatal dose c. Teratology
b. LD50 d. Threshold Limit Value
a. fatal dose
Acute poisoning includes, except:
a. taking a strong poison
b. taking several small doses but frequent
c. taking several small doses at long intervals
d. taking excessive single doses
c. taking several small doses at long intervals
When reporting cases of poisoning like eating in a public restaurant, the cases should
be reported to the:
a. nurse d. public health officer
b. family doctor e. BFAD
c. pharmacist
d. public health officer
,The ff. are mechanism of poison absorption, except:
a. hydrolysis c. filtration
b. endocytosis d. passive diffusion
a. hydrolysis
An example of a Phase 1 Reaction in the metabolism of substances is/are:
a. oxidation c. reduction
b. hydrolysis d. all of the above
d. all of the above
Pneumomediasternum is a complication of the use of:
a. gastric lavage c. hemoperfusion
b. hemodialysis d. emetics
a. gastric lavage
Constipation caused by active charcoal can be relieved by concomitant administration
of
a. glycerol c. laxative
b. water d. none of the above
c. laxative
Contraindication to the use of cathartics are the ff. except:
a. GI hemorrhage c. renal failure
b. corrosive agents d. none of the above
d. none of the above
The percentage of oxygen which is indicated for carbon dioxide poisoning to increase
the conversion of carboxyhemoglobin to hemoglobin and myoglobin and to increase
oxygen saturation of the plasma is:
a. 50% c. 100%
b. 75% d. 10%
c. 100%
Nail polish removers contain
a. aniline c. acetone
b. ammonium hydroxide d. phosphoric acid
c. acetone
Convulsions caused by drug poisoning are most commonly associated with:
a. Phenobarbital c. strychnine
b. diazepam d. chlorpromazine
c. strychnine
Alkanizing the urine with sodium bicarbonate is useful in the treatment of poisoning with:
a. ASA and barbiturates c. amphetamines
b. phencyclidine d. morphine
a. ASA and barbiturates
Activated charcoal may be used in the treatment of these poisoning, except
a. Phenobarbital c. aspirin
b. propoxyphene d. methanol
d. methanol
These statements regarding carbon monoxide poisoning are true except:
a. the oxygen carrying capacity of the blood is decreased
, b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing less
oxygen to the tissues
c. carboxyhemoglobin level of less than 30% produces minimal symptoms
d. treatment with 100% carbon dioxide is effective
d. treatment with 100% carbon dioxide is effective
Ototoxicity may be an adverse reaction of the following, except:
a. streptomycin c. furosemide
b. ethacrynic acid d. tetracyclines
d. tetracyclines
The major routes by which toxic agents gain access to the body are through the ff.,
except:
a. blood d. skin
b. GIT e. parenteral route
c. lungs
a. blood
Acute exposure by inhalation refers to continuous exposure for less than 2 hours, most
frequently for:
a. 2 d. 5
b. 3 e. 6 hrs.
c. 4
c. 4
Dryness of the mouth is a side effect of:
a. atropine c. acetaminophen
b. aspirin d. cimetidine
a. atropine
One group of thiol-containing enzymes that may play a critical role in cell injury and
death as a result of oxidative inactivation (oxidative stress) is:
a. Ca d. Mg
b. Na e. Al transportation alpase
c. K
e. Al transportation alpase
Individuals who are deficient in glucose-6-dehydrogenase experience hemolysis
following the treatment with these drugs, except:
a. dapsone c. primaquine
b. ethacrynic acid d. tetracyclines
d. tetracyclines
It is known as the prussic acid
a. aniline d. iodine
b. hydrocyanic acid e. formaldehyde
c. ethyl alcohol
b. hydrocyanic acid
It is known as the Neutral spirit
a. aniline d. iodine
b. cyanide e. formaldehyde
c. ethyl alcohol
AND ANSWERS WITH COMPLETE SOLUTION
This is obtained from an examination of the tissues and organs of the dead.
a. Experimental evidence c. post-mortem evidence
b. Chemical evidence d. circumstantial evidence
c. post-mortem evidence
Death may result from poisoning due to the following causes, except: a. due to
interference with the carriage of oxygen
b. due to inhibition of the respiratory movements by neuro muscular agents
c. due to interference with the enzyme system utilizing it
d. circulatory failure as a result of cardiac glucosides
c. due to interference with the enzyme system utilizing it
The most serious potential consequence of ingestion of liquid hydrocarbon such as
kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. the aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison
b. the aspiration of the poison into the respiratory tract
The specific antidote for the treatment of poisoning due to oral ingestion of silver nitrate
would be the oral administration of :
a. acetic acid solution
b. normal saline
c. sodium bicarbonate
b. normal saline
Catharsis as a way of removing a poison include the ff. except:
a. increases intestinal injury when a corrosive is ingested
b. is avoided in a patient showing disturbed electrolyte imbalance
c. hypertonic cathartic and enemas are hazardous in the presence of impaired renal
function
d. none of the above
d. none of the above
This is recommended in phenol poisoning as a cathartic but is contraindicated in
poisoning by chlorinated insecticide, since it may increase intestinal absorption
a. magnesium sulfate c. mannitol
b. castor oil d. Fleet's Phospho-soda
b. castor oil
A poison which increases suddenly in its intensity of action after slow or gradual
addition of it is
a. corrosive poison c. true poison
b. cumulative poison d. irritant poison
b. cumulative poison
,Streptomycin can cause:
a. 4th cranial damage c. 8th cranial damage
b. 7th cranial damage d. 6th cranial damage
c. 8th cranial damage
Most accidental poisoning in children is caused by:
a. detergents
b. bleaches
c. crayons
d. insecticides
e. salicylate analgesics
c. crayons
Antidote for iodine poisoning:
a. silver nitrate c. potassium nitrate
b. starch d. sugar
b. starch
The evidences to be saved in nonfatal poisoning are the following, except:
a. lung d. blood
b. urine e. body fat
c. food
a. lung
A specialized field of toxicology that designates an area of professional emphasis within
the realm of medical science.
a. Forensic toxicology c. Environmental toxicology
b. Clinical toxicology d. Regulatory toxicology
b. Clinical toxicology
This is an area of toxicology which is concerned directly with toxicity testing, which
provides necessary information for safety evaluation and regulatory requirements.
a. mechanistic toxicology c. descriptive toxicology
b. regulatory toxicology d. forensic toxicology
c. descriptive toxicology
The quantity of medicine that can kill an organism
a. fatal dose c. Teratology
b. LD50 d. Threshold Limit Value
a. fatal dose
Acute poisoning includes, except:
a. taking a strong poison
b. taking several small doses but frequent
c. taking several small doses at long intervals
d. taking excessive single doses
c. taking several small doses at long intervals
When reporting cases of poisoning like eating in a public restaurant, the cases should
be reported to the:
a. nurse d. public health officer
b. family doctor e. BFAD
c. pharmacist
d. public health officer
,The ff. are mechanism of poison absorption, except:
a. hydrolysis c. filtration
b. endocytosis d. passive diffusion
a. hydrolysis
An example of a Phase 1 Reaction in the metabolism of substances is/are:
a. oxidation c. reduction
b. hydrolysis d. all of the above
d. all of the above
Pneumomediasternum is a complication of the use of:
a. gastric lavage c. hemoperfusion
b. hemodialysis d. emetics
a. gastric lavage
Constipation caused by active charcoal can be relieved by concomitant administration
of
a. glycerol c. laxative
b. water d. none of the above
c. laxative
Contraindication to the use of cathartics are the ff. except:
a. GI hemorrhage c. renal failure
b. corrosive agents d. none of the above
d. none of the above
The percentage of oxygen which is indicated for carbon dioxide poisoning to increase
the conversion of carboxyhemoglobin to hemoglobin and myoglobin and to increase
oxygen saturation of the plasma is:
a. 50% c. 100%
b. 75% d. 10%
c. 100%
Nail polish removers contain
a. aniline c. acetone
b. ammonium hydroxide d. phosphoric acid
c. acetone
Convulsions caused by drug poisoning are most commonly associated with:
a. Phenobarbital c. strychnine
b. diazepam d. chlorpromazine
c. strychnine
Alkanizing the urine with sodium bicarbonate is useful in the treatment of poisoning with:
a. ASA and barbiturates c. amphetamines
b. phencyclidine d. morphine
a. ASA and barbiturates
Activated charcoal may be used in the treatment of these poisoning, except
a. Phenobarbital c. aspirin
b. propoxyphene d. methanol
d. methanol
These statements regarding carbon monoxide poisoning are true except:
a. the oxygen carrying capacity of the blood is decreased
, b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing less
oxygen to the tissues
c. carboxyhemoglobin level of less than 30% produces minimal symptoms
d. treatment with 100% carbon dioxide is effective
d. treatment with 100% carbon dioxide is effective
Ototoxicity may be an adverse reaction of the following, except:
a. streptomycin c. furosemide
b. ethacrynic acid d. tetracyclines
d. tetracyclines
The major routes by which toxic agents gain access to the body are through the ff.,
except:
a. blood d. skin
b. GIT e. parenteral route
c. lungs
a. blood
Acute exposure by inhalation refers to continuous exposure for less than 2 hours, most
frequently for:
a. 2 d. 5
b. 3 e. 6 hrs.
c. 4
c. 4
Dryness of the mouth is a side effect of:
a. atropine c. acetaminophen
b. aspirin d. cimetidine
a. atropine
One group of thiol-containing enzymes that may play a critical role in cell injury and
death as a result of oxidative inactivation (oxidative stress) is:
a. Ca d. Mg
b. Na e. Al transportation alpase
c. K
e. Al transportation alpase
Individuals who are deficient in glucose-6-dehydrogenase experience hemolysis
following the treatment with these drugs, except:
a. dapsone c. primaquine
b. ethacrynic acid d. tetracyclines
d. tetracyclines
It is known as the prussic acid
a. aniline d. iodine
b. hydrocyanic acid e. formaldehyde
c. ethyl alcohol
b. hydrocyanic acid
It is known as the Neutral spirit
a. aniline d. iodine
b. cyanide e. formaldehyde
c. ethyl alcohol
