C785 MODULE 2 QUIZ
1. Which image below shows the carboxyl group of an amino acid
circled?-
: An amino acid consists of an amino group, carboxyl group, a
hydrogen and a variable side chain arranged around a central alpha
carbon atom. The backbone of an amino acid is the entire amino acid
molecule minus the variable side chain. The carboxyl group of an
amino acid is shown as COO_ or COOH attached to a central alpha
carbon atom of the amino acid.
2. Which of the following statements is NOT true about the different levels
of a protein structure?: The interactions between the side chains of the
amino acids make up the secondary level structure of a protein
3. Which statement reflects the role that protein structure can play in the
disease process?: Mutation of an active site amino acid changes an
enzyme's ability to bind a substrate.
4. Aggregation of the proteins is the main reason behind many neurode-
generative diseases. Which one of the following mutations will likely
cause a neurodegenerative disease?: Replacing a polar amino acid with
a non-polar amino acid
5. Which pair (protein interaction and technique) will likely denature a
pro- tein?: Hydrogen bonds/ionic bonds: Change in pH
6. Which one of the following statements is NOT true about protein
structure and stability?: Protein structure is not stabilized by the
1/3
, hydrophobic effect
7. Alkaline phosphatase is produced by bone and liver in the human body.
The amount of alkaline phosphatase in blood can help identify if a patient
potentially has certain types of bone and/or liver-related disease, including
Paget disease, hepatitis, and certain types of cancer. The optimal pH range
for alkaline phosphatase activity is a pH of 8.0 to 10.0. What happens to
the activity of the alkaline phosphatase at a pH of 2?: Significantly
decreases
8. Inhibitors that have a similar structure to a substrate of an enzyme are
most likely to bind to the enzyme's and be a
inhibitor.: active site, competitive
9. When an inhibitor binds reversibly to a site of the enzyme that is not
the active site, what type of inhibition results?: Noncompetitive
inhibition
10. Chymotrypsin is a digestive enzyme that has optimal activity at a
pH of 7.8 and a temperature of 37oC. Which of the following statements
is
true?: The reaction rate for chymotrypsin at a pH of 9.5 is lower than
the reaction rate for chymotrypsin at a pH of 7.8.
2/3
1. Which image below shows the carboxyl group of an amino acid
circled?-
: An amino acid consists of an amino group, carboxyl group, a
hydrogen and a variable side chain arranged around a central alpha
carbon atom. The backbone of an amino acid is the entire amino acid
molecule minus the variable side chain. The carboxyl group of an
amino acid is shown as COO_ or COOH attached to a central alpha
carbon atom of the amino acid.
2. Which of the following statements is NOT true about the different levels
of a protein structure?: The interactions between the side chains of the
amino acids make up the secondary level structure of a protein
3. Which statement reflects the role that protein structure can play in the
disease process?: Mutation of an active site amino acid changes an
enzyme's ability to bind a substrate.
4. Aggregation of the proteins is the main reason behind many neurode-
generative diseases. Which one of the following mutations will likely
cause a neurodegenerative disease?: Replacing a polar amino acid with
a non-polar amino acid
5. Which pair (protein interaction and technique) will likely denature a
pro- tein?: Hydrogen bonds/ionic bonds: Change in pH
6. Which one of the following statements is NOT true about protein
structure and stability?: Protein structure is not stabilized by the
1/3
, hydrophobic effect
7. Alkaline phosphatase is produced by bone and liver in the human body.
The amount of alkaline phosphatase in blood can help identify if a patient
potentially has certain types of bone and/or liver-related disease, including
Paget disease, hepatitis, and certain types of cancer. The optimal pH range
for alkaline phosphatase activity is a pH of 8.0 to 10.0. What happens to
the activity of the alkaline phosphatase at a pH of 2?: Significantly
decreases
8. Inhibitors that have a similar structure to a substrate of an enzyme are
most likely to bind to the enzyme's and be a
inhibitor.: active site, competitive
9. When an inhibitor binds reversibly to a site of the enzyme that is not
the active site, what type of inhibition results?: Noncompetitive
inhibition
10. Chymotrypsin is a digestive enzyme that has optimal activity at a
pH of 7.8 and a temperature of 37oC. Which of the following statements
is
true?: The reaction rate for chymotrypsin at a pH of 9.5 is lower than
the reaction rate for chymotrypsin at a pH of 7.8.
2/3
